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MIRAGE
Thioredoxin reductase 1, cytoplasmic
Summary
- UniProt ID
- Q9JMH6
- Gene Symbol
-
- Trxr1
- Txnrd1
- Gene ID
- 50493
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Cytoplasm
- Disulfide bond
- FAD
- NADP
- Oxidoreductase
- Phosphoprotein
- Redox-active center
- Reference proteome
- Selenocysteine
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| mitochondrion |
| nucleoplasm |
| cytosol |
| fibrillar center |
| GO Term |
|---|
| mesoderm formation |
| gastrulation |
| cell population proliferation |
| cell redox homeostasis |
| GO Term |
|---|
| thioredoxin-disulfide reductase (NADP) activity |
| identical protein binding |
| FAD binding |
| NADPH peroxidase activity |
Sequence
MPVDDCWLYFPASRGRTFVQTVWVAPTCPNCCWFPGFLPPVPRPPHVPRVLLRGPRGAVLPASRPSKTLPSSSQTPCPTDPCICPPPSTPDSRQEKNTQSELPNKKGQLQKLPTMNGSKDPPGSYDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKKVVYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGCUG
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Detoxification of Reactive Oxygen Species | Mus musculus |
| Interconversion of nucleotide di- and triphosphates | Mus musculus |
| Metabolism of ingested MeSeO2H into MeSeH | Mus musculus |
| TP53 Regulates Metabolic Genes | Mus musculus |
