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Integrin alpha-IIb
Summary
- UniProt ID
- Q9QUM0
- Gene Symbol
-
- Itga2b
- Gene ID
- 16399
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0007645
- PubChem
- Q9QUM0
- Re-Glyco
- Q9QUM0
Annotation
- Keyword
-
- Calcium
- Cell adhesion
- Disulfide bond
- Glycoprotein
- Integrin
- Metal-binding
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| external side of plasma membrane |
| cell surface |
| focal adhesion |
| extracellular exosome |
| integrin alphaIIb-beta3 complex |
| GO Term |
|---|
| positive regulation of leukocyte migration |
| cell-matrix adhesion |
| integrin-mediated signaling pathway |
| GO Term |
|---|
| identical protein binding |
| extracellular matrix binding |
| fibrinogen binding |
| metal ion binding |
Sequence
MARASCAWHSLWLLQWTPLFLGPSAVPPVWALNLDSEKFSVYAGPNGSHFGFSVDFHKDKHGSVSIVVGAPRALNASQEETGAVFLCPWKANGGKCNPLLFDLRDETRNLGFQIFQTFKTGQGLGASVVSWNDVIVACAPWQHWNVLEKRDEAEKTPVGGCFLAQLQSGGRAEYSPCRANTMSSVYAESFRGDKRYCEAGFSLAVTQAGELVLGAPGGYFFLGLLARVPIENIISSYRPGTLLWHVSNQRFTYDNSNPVFFDGYRGYSVAVGEFDGDPSTTEYVSGAPTWSWTLGAVEILDSYYQPLHRLHGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPKGPQALSTPTLLLTGTQLYGRFGSAIAPLGDLNRDGYNDIAVAAPYGGPSGQGQVLIFLGQSEGLSPRPSQVLDSPFPTGSGFGFSLRGAVDIDDNGYPDLIVGAYGASKVAVYRAQPVVMATVQLMVQDSLNPTLKNCVLDQTKTPVSCFNIQMCVGATGHNIPQKLHLKAELQLDLQKPRQGRRVLLLASQQASLTLSLDLGGRDKPICHTTGAFLRDEADFRDKLSPIVLSLNVSLPPEETGGAPAVVLHGETHVQEQTRIILDCGEDDLCVPQLRLTATAGDSPLLIGADNVLELKIEAANDGEGAYEAELAVHLPPGAHYMRALSNIEGFERLVCTQKKENESRVALCELGNPMKKDTRIGITMLVSVENLEEAGESVSFQLQVRSKNSQNPNSKVVMLPVAIQAEATVELRGNSFPASLVVAAEEGDREQEDLDRWVSRLEHTYELHNIGPGTVNGLRLLIHIPGQSQPSDLLYILDVQPQGGLLCSTQPSPKVDWKLSTPSPSSIRPVHHQRERRQAFLQGPKPGQQDPVLVSCDGSASCTVVECELREMVRGQRAMVTVQVMLGLSSLRQRPQEQFVLQSHAWFNVSSLPYSVPVVSLPSGQARVQTQLLRALEERAIPVWWVLVGVLGGLLLLTLLVLAMWKAGFFKRNRPPLEEDEEEE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 46 | N-linked (GlcNAc...) asparagine |
|
||
| 75 | N-linked (GlcNAc...) asparagine |
|
||
| 600 | N-linked (GlcNAc...) asparagine |
|
||
| 710 | N-linked (GlcNAc...) asparagine |
|
||
| 957 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ECM proteoglycans | Mus musculus |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | Mus musculus |
| Integrin cell surface interactions | Mus musculus |
| Integrin signaling | Mus musculus |
| MAP2K and MAPK activation | Mus musculus |
| Platelet degranulation | Mus musculus |
| Signal transduction by L1 | Mus musculus |
| p130Cas linkage to MAPK signaling for integrins | Mus musculus |
