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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Poly [ADP-ribose] polymerase 2
Summary
- UniProt ID
- Q9UGN5
- Gene Symbol
-
- PARP2
- ADPRT2
- ADPRTL2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9UGN5
- PubChem
- Q9UGN5
- The Human Metabolome Database
- HMDBP00916
- The O-GlcNAc Database
- Q9UGN5
Annotation
- Keyword
-
- 3D-structure
- ADP-ribosylation
- Acetylation
- Allosteric enzyme
- Alternative splicing
- Chromosome
- DNA repair
- DNA-binding
- Glycosyltransferase
- NAD
- Nucleotidyltransferase
- Nucleus
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| nucleolus |
| site of DNA damage |
| nucleoplasm |
Sequence
MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW
Glycosylation Sites
G31852PQ
G28929VW
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| DNA Damage Recognition in GG-NER | Homo sapiens |
| Dual Incision in GG-NER | Homo sapiens |
| Formation of Incision Complex in GG-NER | Homo sapiens |
| HDR through MMEJ (alt-NHEJ) | Homo sapiens |
| POLB-Dependent Long Patch Base Excision Repair | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:684 | hepatocellular carcinoma | |
| DOID:7148 | rheumatoid arthritis | |
| DOID:769 | neuroblastoma | |
| DOID:811 | lipodystrophy | |
| DOID:8353 | epithelioid malignant peripheral nerve sheath tumor | |
| DOID:9351 | diabetes mellitus | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9452 | steatotic liver disease | |
| DOID:9970 | obesity |
