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Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

Summary

UniProt ID

Q9UL51

Gene Symbol

HCN2
BCNG2

Organism

Homo sapiens (human)

External Links

GlyGen: Q9UL51
PubChem: Q9UL51
The Human Metabolome Database: HMDBP02618
The O-GlcNAc Database: Q9UL51
O-GlcNAcAtlas: Q9UL51

Annotation

Keyword

3D-structure
Ammonia transport
Cell membrane
Disease variant
Epilepsy
Glycoprotein
Ligand-gated ion channel
Methylation
Palmitate
Phosphoprotein
Potassium channel
Reference proteome
Sodium channel
Transmembrane helix
Voltage-gated channel
cAMP-binding

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
regulation of membrane depolarization
cell-cell signaling
regulation of membrane potential
sodium ion transmembrane transport
membrane depolarization during cardiac muscle cell action potential
sodium ion import across plasma membrane
potassium ion transmembrane transport
potassium ion import across plasma membrane
cellular response to cAMP
cellular response to cGMP

Displaying **all 5** entries
GO Term
voltage-gated potassium channel complex
HCN channel complex
plasma membrane
axon
dendrite

Displaying **all 5** entries
GO Term
identical protein binding
cAMP binding
intracellular cAMP-activated cation channel activity
voltage-gated sodium channel activity
voltage-gated potassium channel activity

Annotation information from UniProt.

Sequence

MDARGGGGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSEEAGPAGEPRGSQASFMQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLNSGVFNNQENAIIQEIVKYDREMVQQAELGQRVGLFPPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPLSASQPSLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSASPGAAGGLDPQDSARSRLSSNL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites