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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Long-chain-fatty-acid--CoA ligase 5
Summary
- UniProt ID
- Q9ULC5
- Gene Symbol
-
- ACSL5
- ACS5
- FACL5
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Alternative splicing
- Cell membrane
- Disease variant
- Endoplasmic reticulum
- Fatty acid metabolism
- Ligase
- Magnesium
- Mitochondrion outer membrane
- Phosphoprotein
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| mitochondrion |
| nucleoplasm |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| mitochondrial outer membrane |
| nucleolus |
| plasma membrane |
| membrane |
| GO Term |
|---|
| arachidonate-CoA ligase activity |
| long-chain fatty acid-CoA ligase activity |
| ATP binding |
| oleoyl-CoA ligase activity |
Sequence
MLFIFNFLFSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKYFRTQIDSLYEHIQD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 107 |
|
|||
| 563 |
|
G49108TO
G62765YT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Synthesis of very long-chain fatty acyl-CoAs | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050908 | myelodysplastic syndrome | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:10608 | celiac disease | |
| DOID:1168 | familial hyperlipidemia | |
| DOID:11847 | coronary thrombosis | |
| DOID:1584 | acute chest syndrome | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:2095 | sweat gland cancer | |
| DOID:2224 | essential thrombocythemia |
