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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
E3 ubiquitin-protein ligase CHIP
Summary
- UniProt ID
- Q9WUD1
- Gene Symbol
-
- Stub1
- Chip
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Cytoplasm
- DNA repair
- Isopeptide bond
- Mitochondrion
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- TPR repeat
- Transferase
- Ubl conjugation
- Ubl conjugation pathway
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of mitophagy |
| positive regulation of ERAD pathway |
| GO Term |
|---|
| nuclear inclusion body |
Sequence
MKGKEEKEGGARLGTGGGGSPDKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLTRLIAAERERELEECQRNHEGHEDDGHIRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWVEDY
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Antigen processing: Ubiquitination & Proteasome degradation | Mus musculus |
| Downregulation of ERBB2 signaling | Mus musculus |
| Downregulation of TGF-beta receptor signaling | Mus musculus |
| Regulation of PTEN stability and activity | Mus musculus |
| Regulation of RUNX2 expression and activity | Mus musculus |
| Regulation of TNFR1 signaling | Mus musculus |
| Regulation of necroptotic cell death | Mus musculus |
