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Anaphase-promoting complex subunit 7
Summary
- UniProt ID
- Q9WVM3
- Gene Symbol
-
- Anapc7
- Apc7
- Gene ID
- 56317
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Cytoskeleton
- Mitosis
- Nucleus
- Reference proteome
- Repeat
- TPR repeat
- Ubl conjugation pathway
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| heterochromatin |
| anaphase-promoting complex |
| spindle |
| microtubule cytoskeleton |
| GO Term |
|---|
| enzyme-substrate adaptor activity |
| protein phosphatase binding |
Sequence
MSVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPSQKYQLLVYHADSLFHDKEYRNAVSKYAMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKLDKDAIAVLDGIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAINTICSLEKKSLLRDNVDLLGSLADLYFRAGDSKNSVLKFEQAQMLDPYLIRGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALAQRPDYVKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
Glycosylation Sites
G80920RR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| APC-Cdc20 mediated degradation of Nek2A | Mus musculus |
| APC/C:Cdc20 mediated degradation of Cyclin B | Mus musculus |
| APC/C:Cdc20 mediated degradation of Securin | Mus musculus |
| APC/C:Cdc20 mediated degradation of mitotic proteins | Mus musculus |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | Mus musculus |
| Antigen processing: Ubiquitination & Proteasome degradation | Mus musculus |
| Assembly of the pre-replicative complex | Mus musculus |
| Autodegradation of Cdh1 by Cdh1:APC/C | Mus musculus |
| CDK-mediated phosphorylation and removal of Cdc6 | Mus musculus |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050888 | syndromic intellectual disability |
