Sialic acid-binding Ig-like lectin 7

Summary
UniProt ID
Q9Y286
Gene Symbol
  • SIGLEC7
  • AIRM1
Organism
Homo sapiens (human)
External Links
GlyConnect
GlyGen
Q9Y286
PubChem
Q9Y286
The Human Metabolome Database
HMDBP02570
The O-GlcNAc Database
Q9Y286
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell adhesion
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Lectin
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying 1 entry
GO Term
cell adhesion
Displaying 1 entry
GO Term
plasma membrane
Sequence
MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPPMISWMGTSVSPLHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSEIKIPK
Glycosylation Sites
Displaying all 9 entries
Position Description PubMed ID GlyTouCan ID Source
105 N-linked (GlcNAc...) asparagine
142 N-linked (GlcNAc...) asparagine
165 N-linked (GlcNAc...) asparagine
229 N-linked (GlcNAc...) asparagine
235 N-linked (GlcNAc...) asparagine
242 N-linked (GlcNAc...) asparagine
260 N-linked (GlcNAc...) asparagine
334 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Homo sapiens
Disease
Displaying entries 11 - 20 of 225 in total
DO ID Disease Name Source
DOID:0060672 Grn-related frontotemporal lobar degeneration with Tdp43 inclusions
DOID:289 endometriosis
DOID:0060843 hereditary neuropathy with liability to pressure palsies
DOID:0060891 Parkinson's disease 19A
DOID:0060895 Parkinson's disease 4
DOID:0060896 Parkinson's disease 23
DOID:0070161 hereditary sensory and autonomic neuropathy type 2
DOID:0080199 colorectal carcinoma
DOID:0080348 Alzheimer's disease 1
DOID:0090003 agenesis of the corpus callosum with peripheral neuropathy

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024