Sialic acid-binding Ig-like lectin 9

Summary
UniProt ID
Q9Y336
Gene Symbol
  • SIGLEC9
Organism
Homo sapiens (human)
External Links
PubChem
Q9Y336
The Human Metabolome Database
HMDBP14278
Annotation
Keyword
  • Alternative splicing
  • Cell adhesion
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Lectin
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 2 entries
GO Term
cell adhesion
cell surface receptor signaling pathway
Displaying all 2 entries
GO Term
plasma membrane
secretory granule membrane
Displaying all 2 entries
GO Term
carbohydrate binding
sialic acid binding
Sequence
MLLLLLPLLWGRERAEGQTSKLLTMQSSVTVQEGLCVHVPCSFSYPSHGWIYPGPVVHGYWFREGANTDQDAPVATNNPARAVWEETRDRFHLLGDPHTKNCTLSIRDARRSDAGRYFFRMEKGSIKWNYKHHRLSVNVTALTHRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMISWIGTSVSPLDPSTTRSSVLTLIPQPQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQNLTMTVFQGDGTVSTVLGNGSSLSLPEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPSQPSNPGVLELPWVHLRDAAEFTCRAQNPLGSQQVYLNVSLQSKATSGVTQGVVGGAGATALVFLSFCVIFVVVRSCRKKSARPAAGVGDTGIEDANAVRGSASQGPLTEPWAEDSPPDQPPPASARSSVGEGELQYASLSFQMVKPWDSRGQEATDTEYSEIKIHR
Glycosylation Sites
Displaying all 8 entries
Position Description PubMed ID GlyTouCan ID Source
101 N-linked (GlcNAc...) asparagine
138 N-linked (GlcNAc...) asparagine
161 N-linked (GlcNAc...) asparagine
225 N-linked (GlcNAc...) asparagine
231 N-linked (GlcNAc...) asparagine
238 N-linked (GlcNAc...) asparagine
256 N-linked (GlcNAc...) asparagine
334 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Homo sapiens
Neutrophil degranulation Homo sapiens
Disease
Displaying entries 11 - 20 of 31 in total
DO ID Disease Name Source
DOID:2348 arteriosclerotic cardiovascular disease
DOID:2349 arteriosclerosis
DOID:2841 asthma
DOID:305 carcinoma
DOID:3068 glioblastoma
DOID:3070 high grade glioma
DOID:3074 giant cell glioblastoma
DOID:3083 chronic obstructive pulmonary disease
DOID:381 arthropathy
DOID:3908 lung non-small cell carcinoma

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024