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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Ficolin-3
Summary
- UniProt ID
- O75636
- Gene Symbol
-
- FCN3
- FCNH
- HAKA1
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011246
- GlyConnect
- GlyGen
- O75636
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Collagen
- Complement activation lectin pathway
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Hydroxylation
- Lectin
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| signaling receptor binding |
| metal ion binding |
| carbohydrate derivative binding |
| carbohydrate binding |
| antigen binding |
Sequence
MDLLWILPSLWLLLLGGPACLKTQEHPSCPGPRELEASKVVLLPSCPGAPGSPGEKGAPGPQGPPGPPGKMGPKGEPGDPVNLLRCQEGPRNCRELLSQGATLSGWYHLCLPEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRYAVSEAAAHKYGIDWASGRGVGHPYRRVRMMLR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 189 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Ficolins bind to repetitive carbohydrate structures on the target cell surface | Homo sapiens |
| Initial triggering of complement | Homo sapiens |
| Lectin pathway of complement activation | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:419 | scleroderma | |
| DOID:5844 | myocardial infarction | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0060192 | Crohn's colitis | |
| DOID:0060295 | complement component 2 deficiency | |
| DOID:0060297 | complement component 4a deficiency | |
| DOID:0060298 | complement component 4b deficiency | |
| DOID:0060299 | complement component 6 deficiency | |
| DOID:0060300 | complement component 7 deficiency | |
| DOID:0060301 | type I complement component 8 deficiency |
