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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Ficolin-3
Summary
- UniProt ID
- O75636
- Gene Symbol
-
- FCN3
- FCNH
- HAKA1
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011246
- GlyConnect
- GlyGen
- O75636
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Collagen
- Complement activation lectin pathway
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Hydroxylation
- Lectin
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| signaling receptor binding |
| metal ion binding |
| carbohydrate derivative binding |
| carbohydrate binding |
| antigen binding |
Sequence
MDLLWILPSLWLLLLGGPACLKTQEHPSCPGPRELEASKVVLLPSCPGAPGSPGEKGAPGPQGPPGPPGKMGPKGEPGDPVNLLRCQEGPRNCRELLSQGATLSGWYHLCLPEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRYAVSEAAAHKYGIDWASGRGVGHPYRRVRMMLR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 189 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Ficolins bind to repetitive carbohydrate structures on the target cell surface | Homo sapiens |
| Initial triggering of complement | Homo sapiens |
| Lectin pathway of complement activation | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3393 | coronary artery disease | |
| DOID:3571 | liver cancer | |
| DOID:3891 | placental insufficiency | |
| DOID:399 | tuberculosis | |
| DOID:4001 | ovarian carcinoma | |
| DOID:418 | systemic scleroderma | |
| DOID:5854 | silent myocardial infarction | |
| DOID:612 | primary immunodeficiency disease | |
| DOID:626 | complement deficiency | |
| DOID:684 | hepatocellular carcinoma |
