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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Plasma kallikrein
Summary
- UniProt ID
- P03952
- Gene Symbol
-
- KLKB1
- KLK3
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011343
- GlyConnect
- GlyGen
- P03952
- PubChem
- P03952
- The Human Metabolome Database
- HMDBP02080
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Fibrinolysis
- Glycoprotein
- Inflammatory response
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of fibrinolysis |
| zymogen activation |
| Factor XII activation |
| plasminogen activation |
| fibrinolysis |
| proteolysis |
| blood coagulation |
| GO Term |
|---|
| extracellular region |
| extracellular space |
| plasma membrane |
| extracellular exosome |
| GO Term |
|---|
| serine-type endopeptidase activity |
Sequence
MILFKQATYFISLFATVSCGCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLFSFLPASSINDMEKRFGCFLKDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVDMRGVNFNVSKVSSVEECQKRCTNNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIKVLSNVESGFSLKPCALSEIGCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFFTFYTNVWKIESQRNVCLLKTSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGVDFGGEELNVTFVKGVNVCQETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Homo sapiens |
| Defective SERPING1 causes hereditary angioedema | Homo sapiens |
| Defective factor XII causes hereditary angioedema | Homo sapiens |
| Intrinsic Pathway of Fibrin Clot Formation | Homo sapiens |
