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MIRAGE
Intrinsic Pathway of Fibrin Clot Formation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
KNGKNG:C1q binding protein tetramerC1q binding protein tetramerprekallikrein:kininogen:C1q binding protein tetramerKLKB1(20-638)kallikrein:kininogen:C1q binding protein tetramerPlasma kallikreinBradykininactivated kininogen:C1q binding protein tetramerfactor XIIFXIIaGPIb-IX-Vfactor XI:GPIb-IX-V complexfactor XIfactor XIa:GPIb:GPIX:GPV complexF9(29-461)factor IXF9(192-226)factor IXaFactor VIII precursorfactor VIIIvon Willibrand factor multimerfactor VIII:von Willebrand factor multimerFIIaFactor IIa inhibitors (compounds):IIaFactor IIa inhibitors (compounds)Factor IIa inhibitors (peptide):IIaFactor IIa inhibitors (peptide)F8(1668-1708)factor VIIIafactor VIIIafactor IXafactor VIIIa:factor IXafactor XF10(183-234)Ca2+factor XaF8(392-759)factor VIIIa A1:A3-C1-C2C1InhC1Inhkallikrein:C1Inhfactor XIIa:C1Inhkallikrein:alpha2-macroglobulinA2M tetramer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 1 - 10 of 23 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
P00451 Coagulation factor VIII
  • F8
  • F8C
 view
P00734 Prothrombin
  • F2
 view
P00740 Coagulation factor IX
  • F9
 view
P00742 Coagulation factor X
  • F10
 view
P00748 Coagulation factor XII
  • F12
 view
P01008 Antithrombin-III
  • AT3
  • SERPINC1
 view
P01023 Alpha-2-macroglobulin
  • A2M
  • CPAMD5
 view
P01042 Kininogen-1
  • BDK
  • KNG
  • KNG1
 view
P03951 Coagulation factor XI
  • F11
 view
P03952 Plasma kallikrein
  • KLK3
  • KLKB1
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025