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MIRAGE
Antithrombin-III

Summary
UniProt ID
P01008
Gene Symbol
  • AT3
  • PRO0309
  • SERPINC1
Gene ID
462
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011285
GlyConnect
GlyGen
P01008
PubChem
P01008
The Human Metabolome Database
HMDBP01724
RaftProt
P01008
Re-Glyco
P01008
Annotation
Keyword
  • 3D-structure
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Heparin-binding
  • Phosphoprotein
  • Reference proteome
  • Secreted
  • Serine protease inhibitor
  • Signal
  • Thrombophilia
Gene Ontology (GO)
Displaying all 7 entries
GO Term
extracellular region
extracellular space
plasma membrane
collagen-containing extracellular matrix
endoplasmic reticulum lumen
extracellular exosome
blood microparticle
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
blood coagulation
regulation of blood coagulation
Annotation information from UniProt.
Sequence
MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 7 entries
Position Description PubMed ID GlyTouCan ID Source
128 N-linked (GlcNAc...) asparagine
167 N-linked (GlcNAc...) asparagine
176
187 N-linked (GlcNAc...) (complex) asparagine
224 N-linked (GlcNAc...) asparagine
418
460
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
Common Pathway of Fibrin Clot Formation Homo sapiens
Intrinsic Pathway of Fibrin Clot Formation Homo sapiens
Post-translational protein phosphorylation Homo sapiens
Regulation of IGF Activity by IGFBP Homo sapiens
Disease
Displaying all 5 entries
DO ID Disease Name Source
DOID:0060903 thrombosis
DOID:11247 disseminated intravascular coagulation
DOID:14115 toxic shock syndrome
DOID:3755 antithrombin III deficiency
DOID:8805 intermediate coronary syndrome
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025