Common Pathway of Fibrin Clot Formation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Factor Xa inhibitorsfactor Xa:Factor Xa inhibitorsfactor Xa10xCbxE-F210xCbxE-F2(44-327)FIIaF5factor VaF5(738-1573)factor XaVa:XaVa:Xa:Factor Xa inhibitorsFibrinogenFGA(20-35)fibrin monomerFGB(31-44)fibrin multimerfactor XIIIF13A1(1-37)factor XIII cleaved tetramerF13Bfactor XIIIaCa2+fibrin multimer, crosslinkedNH4+AT3SERPINC1:SERPINC1 activatorsSERPINC1 activatorsthrombin:SERPINC1:SERPINC1 activatorsthrombin:cleaved SERPINC1:SERPINC1 activatorsthrombin:cleaved SERPINC1activated thrombin:thrombomodulinTHBDEPCRPROCR:Protein CProtein CPROC(200-211)PROCR:Activated protein CActivated protein Cprotein SActivated protein C:Protein Sfactor Vi intermediate formF5(535-737)F5(335-534)factor Vifactor VIIIaInactivated factor VIIIF8(356-372)F8(582-640)SERPIND1activated thrombin (factor IIa):SERPIND1SERPINE2:GAGSERPINE2:GAG:activated thrombin (factor IIa)activated thrombin (factor IIa)SERPINA5SERPINA5:Activated protein CF2R(42-425)PROCR:Activated protein C:F2RPROCR(18-?):Activated protein CsEPCRPROCR(18-?):PRTN3:CD177PRTN3:CD177
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
a simple tooltip

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.2.1

Last updated: April 7, 2025