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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Complement component C8 alpha chain
Summary
- UniProt ID
- P07357
- Gene Symbol
-
- C8A
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011419
- GlyConnect
- GlyGen
- P07357
- PubChem
- P07357
- The O-GlcNAc Database
- P07357
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cleavage on pair of basic residues
- Complement alternate pathway
- Direct protein sequencing
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Membrane attack complex
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane beta strand
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| plasma membrane |
| membrane |
| extracellular exosome |
| membrane attack complex |
| blood microparticle |
| GO Term |
|---|
| protein-containing complex binding |
| complement binding |
- Site Annotations
| Position | Description |
|---|---|
| 43 | Not glycosylated |
Sequence
MFAVVFFILSLMTCQPGVTAQEKVNQRVRRAATPAAVTCQLSNWSEWTDCFPCQDKKYRHRSLLQPNKFGGTICSGDIWDQASCSSSTTCVRQAQCGQDFQCKETGRCLKRHLVCNGDQDCLDGSDEDDCEDVRAIDEDCSQYEPIPGSQKAALGYNILTQEDAQSVYDASYYGGQCETVYNGEWRELRYDSTCERLYYGDDEKYFRKPYNFLKYHFEALADTGISSEFYDNANDLLSKVKKDKSDSFGVTIGIGPAGSPLLVGVGVSHSQDTSFLNELNKYNEKKFIFTRIFTKVQTAHFKMRKDDIMLDEGMLQSLMELPDQYNYGMYAKFINDYGTHYITSGSMGGIYEYILVIDKAKMESLGITSRDITTCFGGSLGIQYEDKINVGGGLSGDHCKKFGGGKTERARKAMAVEDIISRVRGGSSGWSGGLAQNRSTITYRSWGRSLKYNPVVIDFEMQPIHEVLRHTSLGPLEAKRQNLRRALDQYLMEFNACRCGPCFNNGVPILEGTSCRCQCRLGSLGAACEQTQTEGAKADGSWSCWSSWSVCRAGIQERRRECDNPAPQNGGASCPGRKVQTQAC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 437 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation of Complement cascade | Homo sapiens |
| Terminal pathway of complement | Homo sapiens |
