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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Furin
Summary
- UniProt ID
- P23188
- Gene Symbol
-
- Furin
- Fur
- Pcsk3
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003495
- GlyGen
- P23188
- PubChem
- P23188
Annotation
- Keyword
-
- 3D-structure
- Autocatalytic cleavage
- Calcium
- Cell membrane
- Cleavage on pair of basic residues
- Disulfide bond
- Endosome
- Glycoprotein
- Golgi apparatus
- Heparin-binding
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Transmembrane helix
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| extracellular region |
| plasma membrane |
| membrane |
| endoplasmic reticulum membrane |
| endosome membrane |
| Golgi cisterna |
| early endosome |
| endoplasmic reticulum lumen |
| trans-Golgi network |
Sequence
MELRSWLLWVVAAAGAVVLLAADAQGQKIFTNTWAVHIPGGPAVADRVAQKHGFHNLGQIFGDYYHFWHRAVTKRSLSPHRPRHSRLQREPQVKWLEQQVAKRRAKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKEAWAQGFTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNADDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIVEILVEPKDIGKRLEVRKAVTACLGEPNHITRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPAGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLSTPPESSGCKTLTSSQACVVCEEGYSLHQKSCVQHCPPGFIPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCLSCPSHASLDPVEQTCSRQSQSSRESRPQQQPPALRPEVEMEPRLQAGLASHLPEVLAGLSCLIIVLIFGIVFLFLHRCSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGRGERTAFIKDQSAL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 440 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Mus musculus |
| Assembly of active LPL and LIPC lipase complexes | Mus musculus |
| Collagen degradation | Mus musculus |
| Elastic fibre formation | Mus musculus |
| NGF processing | Mus musculus |
| Pre-NOTCH Processing in Golgi | Mus musculus |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | Mus musculus |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | Mus musculus |
| Signaling by PDGF | Mus musculus |
| TGF-beta receptor signaling activates SMADs | Mus musculus |
