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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Semaphorin-7A
Summary
- UniProt ID
- O75326
- Gene Symbol
-
- SEMA7A
- CD108
- SEMAL
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011240
- GlyConnect
- GlyGen
- O75326
- PubChem
- O75326
- RaftProt
- O75326
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Developmental protein
- Differentiation
- Disease variant
- Disulfide bond
- GPI-anchor
- Immunoglobulin domain
- Inflammatory response
- Intrahepatic cholestasis
- Methylation
- Neurogenesis
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| axon extension |
| semaphorin-plexin signaling pathway |
| positive regulation of axon extension |
| axon guidance |
| integrin-mediated signaling pathway |
| negative chemotaxis |
| positive regulation of ERK1 and ERK2 cascade |
| GO Term |
|---|
| plasma membrane |
| membrane |
| external side of plasma membrane |
| GO Term |
|---|
| semaphorin receptor binding |
| chemorepellent activity |
| integrin binding |
Sequence
MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKGHVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTVNIGSTKGSCLDKRDCENYITLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSERSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHACALAASLWLGVLPTLTLGLLVH
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Other semaphorin interactions | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0090094 | hypogonadotropic hypogonadism 1 with or without anosmia | |
| DOID:0110858 | polycystic kidney disease 1 | |
| DOID:10763 | hypertension | |
| DOID:10825 | essential hypertension | |
| DOID:10845 | St. Louis encephalitis | |
| DOID:11504 | autonomic neuropathy | |
| DOID:11832 | visual epilepsy | |
| DOID:12123 | postinflammatory pulmonary fibrosis | |
| DOID:12382 | complex partial epilepsy | |
| DOID:12894 | Sjogren's syndrome |
