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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Folate receptor alpha
Summary
- UniProt ID
- P15328
- Gene Symbol
-
- FOLR1
- FOLR
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011537
- GlyConnect
- GlyGen
- P15328
- PubChem
- P15328
- The Human Metabolome Database
- HMDBP02326
- The O-GlcNAc Database
- P15328
- RaftProt
- P15328
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Endosome
- Folate-binding
- GPI-anchor
- Neurodegeneration
- Receptor
- Reference proteome
- Secreted
- Signal
- Transport
- Gene Ontology (GO)
| GO Term |
|---|
| fusion of sperm to egg plasma membrane involved in single fertilization |
| folic acid transport |
| axon regeneration |
| sperm-egg recognition |
| regulation of canonical Wnt signaling pathway |
| GO Term |
|---|
| Golgi membrane |
| nucleus |
| plasma membrane |
| membrane |
| transport vesicle |
| extracellular exosome |
| basolateral plasma membrane |
| apical plasma membrane |
| clathrin-coated vesicle |
| brush border membrane |
| GO Term |
|---|
| signaling receptor activity |
| folic acid receptor activity |
| folic acid binding |
Sequence
MAQRMTTQLLLLLVWVAVVGEAQTRIAWARTELLNVCMNAKHHKEKPGPEDKLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQVDQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPFHFYFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMSGAGPWAAWPFLLSLALMLLWLLS
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| COPI-mediated anterograde transport | Homo sapiens |
| COPII-mediated vesicle transport | Homo sapiens |
| Cargo concentration in the ER | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2871 | endometrial carcinoma | |
| DOID:2893 | cervix carcinoma | |
| DOID:2962 | Cockayne syndrome | |
| DOID:305 | carcinoma | |
| DOID:3068 | glioblastoma | |
| DOID:3074 | giant cell glioblastoma | |
| DOID:3347 | osteosarcoma | |
| DOID:3376 | bone osteosarcoma | |
| DOID:3490 | Noonan syndrome | |
| DOID:3498 | pancreatic ductal adenocarcinoma |
