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Interleukin-6 receptor subunit beta

Summary

UniProt ID

P40189

Gene Symbol

IL6ST

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011673

GlyConnect

GlyGen

P40189

PubChem

P40189

The O-GlcNAc Database

P40189

O-GlcNAcAtlas

P40189

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Host-virus interaction
Immunoglobulin domain
Phosphoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Gene Ontology (GO)

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GO Term
positive regulation of acute inflammatory response
positive regulation of adaptive immune response
glycogen metabolic process
positive regulation of cell population proliferation
cytokine-mediated signaling pathway
positive regulation of cardiac muscle hypertrophy
response to cytokine
positive regulation of T cell proliferation
negative regulation of apoptotic process
negative regulation of neuron apoptotic process

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GO Term
extracellular region
extracellular space
plasma membrane
membrane
dendrite
neuronal cell body
receptor complex
extracellular exosome
membrane raft
interleukin-6 receptor complex

Displaying entries **1 - 10** of 14 in total

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GO Term
cytokine receptor activity
cytokine binding
protein tyrosine kinase activator activity
identical protein binding
interleukin-27 receptor activity
ciliary neurotrophic factor receptor activity
interleukin-6 receptor activity
interleukin-11 receptor activity
interleukin-11 binding
interleukin-6 binding

Annotation information from UniProt.

Sequence

MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEGMPKSYLPQTVRQGGYMPQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
379		23586699
383		23586699

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
IL-6-type cytokine receptor ligand interactions	Homo sapiens
Interleukin-27 signaling	Homo sapiens
Interleukin-35 Signalling	Homo sapiens
Interleukin-6 signaling	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

International Collaboration

Acknowledgements