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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Prostaglandin-H2 D-isomerase
Summary
- UniProt ID
- P41222
- Gene Symbol
-
- PTGDS
- PDS
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011676
- GlyConnect
- GlyGen
- P41222
- PubChem
- P41222
- SwissLipids
- The Human Metabolome Database
- HMDBP01576
- The O-GlcNAc Database
- P41222
- O-GlcNAcAtlas
- P41222
Annotation
- Keyword
-
- 3D-structure
- Cytoplasm
- Direct protein sequencing
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Golgi apparatus
- Isomerase
- Mast cell degranulation
- Membrane
- Nucleus
- Prostaglandin biosynthesis
- Reference proteome
- Secreted
- Signal
- Transport
- Gene Ontology (GO)
| GO Term |
|---|
| prostaglandin-D synthase activity |
| retinoid binding |
| fatty acid binding |
Sequence
MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMTEQ
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | Homo sapiens |
| Transcriptional regulation of testis differentiation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14525 | Reye syndrome | |
| DOID:14686 | Axenfeld-Rieger syndrome | |
| DOID:1470 | major depressive disorder | |
| DOID:150 | disease of mental health | |
| DOID:1520 | colon carcinoma | |
| DOID:1595 | melancholic depression | |
| DOID:1596 | depressive disorder | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:1749 | squamous cell carcinoma |
