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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
MHC class I polypeptide-related sequence A
Summary
- UniProt ID
- Q29983
- Gene Symbol
-
- MICA
- PERB11.1
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011976
- GlyConnect
- GlyGen
- Q29983
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Cell membrane
- Cytolysis
- Cytoplasm
- Disulfide bond
- Glycoprotein
- Host-virus interaction
- Immunoglobulin domain
- Palmitate
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| natural killer cell mediated cytotoxicity |
| defense response to bacterium |
| gamma-delta T cell activation |
| negative regulation of natural killer cell activation |
| negative regulation of natural killer cell mediated cytotoxicity |
| GO Term |
|---|
| external side of plasma membrane |
| cell surface |
| extracellular space |
| cytoplasm |
| plasma membrane |
| GO Term |
|---|
| signaling receptor binding |
| natural killer cell lectin-like receptor binding |
| peptide antigen binding |
Sequence
MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRDATQLGFQPLMSDLGSTGSTEGA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4473 | sarcomatoid renal cell carcinoma | |
| DOID:4647 | trilateral retinoblastoma | |
| DOID:4648 | familial retinoblastoma | |
| DOID:4766 | embryoma | |
| DOID:4840 | sebaceous carcinoma | |
| DOID:4903 | granular cell carcinoma | |
| DOID:4905 | pancreatic carcinoma | |
| DOID:4929 | tubular adenocarcinoma | |
| DOID:5076 | mixed glioma | |
| DOID:5082 | liver cirrhosis |
