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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase
Summary
- UniProt ID
- Q92187
- Gene Symbol
-
- ST8SIA4
- PST
- PST1
- SIAT8D
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0012443
- GlyGen
- Q92187
- The Human Metabolome Database
- HMDBP14324
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Disulfide bond
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Reference proteome
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| extracellular region |
| Golgi apparatus |
| GO Term |
|---|
| sialyltransferase activity |
| alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity |
| sialic acid binding |
Sequence
MRSIRKRWTICTISLLLIFYKTKEIARTEEHQETQLIGDGELSLSRSLVNSSDKIIRKAGSSIFQHNVEGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKCVKQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 219 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| NCAM1 interactions | Homo sapiens |
| Sialic acid metabolism | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14330 | Parkinson's disease | |
| DOID:1470 | major depressive disorder | |
| DOID:1574 | alcohol use disorder | |
| DOID:1595 | melancholic depression | |
| DOID:1596 | depressive disorder | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:1749 | squamous cell carcinoma | |
| DOID:1837 | diabetic ketoacidosis | |
| DOID:1936 | atherosclerosis |
