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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Toll-like receptor 4
Summary
- UniProt ID
- Q9QUK6
- Gene Symbol
-
- Tlr4
- Lps
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0007644
- GlyGen
- Q9QUK6
- PubChem
- Q9QUK6
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cell projection
- Disease variant
- Disulfide bond
- Endosome
- Glycoprotein
- Inflammatory response
- Innate immunity
- Leucine-rich repeat
- NAD
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of chemokine (C-X-C motif) ligand 2 production |
Sequence
MMPPWLLARTLIMALFFSCLTPGSLNPCIEVVPNITYQCMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWHGLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLEELQHLDFQHSTLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLSTLDCSFNRIETSKGILQHFPKSLAFFNLTNNSVACICEHQKFLQWVKEQKQFLVNVEQMTCATPVEMNTSLVLDFNNSTCYMYKTIISVSVVSVIVVSTVAFLIYHFYFHLILIAGCKKYSRGESIYDAFVIYSSQNEDWVRNELVKNLEEGVPRFHLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSRHFIQSRWCIFEYEIAQTWQFLSSRSGIIFIVLEKVEKSLLRQQVELYRLLSRNTYLEWEDNPLGRHIFWRRLKNALLDGKASNPEQTAEEEQETATWT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 237 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | Mus musculus |
| Heme signaling | Mus musculus |
| IKK complex recruitment mediated by RIP1 | Mus musculus |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | Mus musculus |
| Ligand-dependent caspase activation | Mus musculus |
| MyD88-independent TLR4 cascade | Mus musculus |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | Mus musculus |
| Regulation of TLR by endogenous ligand | Mus musculus |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | Mus musculus |
| TRIF-mediated programmed cell death | Mus musculus |
