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Heat shock protein HSP 90-beta

Summary

UniProt ID

P34058

Gene Symbol

Hsp90ab1
Hsp84
Hspc3
Hspcb

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P34058
PubChem: P34058
The O-GlcNAc Database: P34058

Annotation

Keyword

ATP-binding
Acetylation
Cell membrane
Chaperone
Cytoplasm
Direct protein sequencing
Glycoprotein
Methylation
Nucleus
Phosphoprotein
Reference proteome
S-nitrosylation
Secreted
Stress response
Ubl conjugation

Gene Ontology (GO)

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GO Term
placenta development
response to organic substance
regulation of cell cycle
supramolecular fiber organization
regulation of protein localization
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
positive regulation of cell differentiation
negative regulation of protein metabolic process
cellular response to organic cyclic compound

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GO Term
extracellular region
nucleus
cytoplasm
lysosomal membrane
plasma membrane
protein-containing complex
melanosome
neuronal cell body
ooplasm
HSP90-CDC37 chaperone complex

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GO Term
peptide binding
heterocyclic compound binding
kinase binding
protein kinase binding
histone methyltransferase binding
sulfonylurea receptor binding
heat shock protein binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity

Annotation information from UniProt.

Sequence

MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKEDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVTAEEPSAAVPDEIPPLEGDEDASRMEEVD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	GlyTouCan ID	Source
434	O-linked (GlcNAc) serine		UniProt GlyGen
452	O-linked (GlcNAc) serine		UniProt GlyGen
		G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Aryl hydrocarbon receptor signalling	Rattus norvegicus
Attenuation phase	Rattus norvegicus
DDX58/IFIH1-mediated induction of interferon-alpha/beta	Rattus norvegicus
ESR-mediated signaling	Rattus norvegicus
Estrogen-dependent gene expression	Rattus norvegicus
HSF1 activation	Rattus norvegicus
HSF1-dependent transactivation	Rattus norvegicus
HSP90 chaperone cycle for SHRs	Rattus norvegicus
Neutrophil degranulation	Rattus norvegicus
RHOBTB2 GTPase cycle	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Annotation

International Collaboration

Acknowledgements