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Signal transducer and activator of transcription 3

Summary

UniProt ID

P42227

Gene Symbol

Stat3
Aprf

Organism

Mus musculus (house mouse)

External Links

GlyGen: P42227
PubChem: P42227
The O-GlcNAc Database: P42227
RaftProt: P42227
O-GlcNAcAtlas: P42227

Annotation

Keyword

3D-structure
Acetylation
Activator
Acute phase
Alternative splicing
Cytoplasm
DNA-binding
Direct protein sequencing
Nucleus
Phosphoprotein
Reference proteome
SH2 domain
Transcription regulation

Gene Ontology (GO)

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GO Term
mRNA transcription by RNA polymerase II
phosphatidylinositol 3-kinase/protein kinase B signal transduction
response to leptin
temperature homeostasis
defense response
inflammatory response
cell population proliferation
positive regulation of cell population proliferation
negative regulation of cell population proliferation
gene expression

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GO Term
cytoplasm
mitochondrial inner membrane
cytosol
nucleoplasm
transcription regulator complex
RNA polymerase II transcription regulator complex
postsynaptic density
Schaffer collateral - CA1 synapse
chromatin
nucleus

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GO Term
DNA binding
protein kinase binding
chromatin DNA binding
CCR5 chemokine receptor binding
nuclear glucocorticoid receptor binding
identical protein binding
protein homodimerization activity
protein dimerization activity
transcription cis-regulatory region binding
DNA-binding transcription factor activity, RNA polymerase II-specific

Annotation information from UniProt.

Sequence

MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMDLTSECATSPM

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	GlyTouCan ID	Source
401	G97993TU	GlyGen
714	G49108TO	GlyGen The O-GlcNAc Database
716	G49108TO	GlyGen
717	G49108TO	GlyGen The O-GlcNAc Database
719	G49108TO	GlyGen The O-GlcNAc Database
721	G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Downstream signal transduction	Mus musculus
Interleukin-10 signaling	Mus musculus
Interleukin-15 signaling	Mus musculus
Interleukin-20 family signaling	Mus musculus
Interleukin-21 signaling	Mus musculus
Interleukin-23 signaling	Mus musculus
Interleukin-27 signaling	Mus musculus
Interleukin-35 Signalling	Mus musculus
Interleukin-37 signaling	Mus musculus
Interleukin-4 and Interleukin-13 signaling	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements