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Histone lysine demethylase PHF8
Summary
- UniProt ID
- Q80TJ7
- Gene Symbol
-
- Kiaa1111
- Phf8
- Gene ID
- 320595
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Alternative splicing
- Cell cycle
- Chromatin regulator
- Dioxygenase
- Iron
- Nucleus
- Phosphoprotein
- Reference proteome
- Transcription regulation
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| nucleolus |
| nuclear membrane |
| nucleoplasm |
Sequence
MASVPVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNCEVLHGPSIMKKRRGSSKGHDNHKGKPLKTGSSMFIRELRGRTFDSSDEVILKPTGSQLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVARQADCKMKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPRIVRKLSWVENLWPEECVFERPNVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQNEMFFGDQVEKCYKCSVKQGQTLFIPTGWIHAVLTPVDCLAFGGNFLHSLNIEMQLKAYEIEKRLSTADLFKFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTKKEALPDHEDEIPETVRTVQLIKDLAREIRLVEDIFQQNVGKTSNIFGLQRIFPAGSIPLTKPAHSTSVSMSKLSLPSKNGSKKKGLKPKDIFKKAERKGKQSSALGPAGQLSYNLMDPYSHQALKTGPSQKAKFNMSGTSLNDSDDDSADMDLDGSENPLALLMANGSTKRMKSVSKSRRAKIAKKVDSARLVAEQVMGDEFDLDSDDELQIDERLGKEKANLLIRSKFPRKLPRAKPCSDPNRIREPGEVEFDIEEDYTTDEDMVEGVESKLGNGSGAGGILDLLKASRQVGGPDYAALTEAPASPSTQEAIQGMLCMANLQSSSSSPATSSLQAWWTGGQERSSGSSSSGLGTVSSSPASQRTPGKRPIKRPAYWKNESEEEENASLDEQDSLGACFKDAEYIYPSLESDDDDPALKSRPKKKKNSDDAPWSPKARVTPTLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQKAQKKKYIKKKPLLKEVEQPRPQDSNPIMTMPAPTVATTPQPDTSSSPQPPPEPKQEALSGSLADHEYTARPNAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSSQAGQGKRPKKGLATAKQRLGRILKIHRNGKLLL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 863 |
|
|||
| 870 |
|
|||
| 920 |
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| HDMs demethylate histones | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060812 | syndromic X-linked intellectual disability Siderius type |
