GlyCosmos Portal

Submissions

D-2-hydroxyglutarate dehydrogenase, mitochondrial

Summary

UniProt ID

Q8N465

Gene Symbol

D2HGD
D2HGDH

Gene ID

728294

Organism

Homo sapiens (human)

External Links

GlyGen: Q8N465
PubChem: Q8N465
The Human Metabolome Database: HMDBP02431
The O-GlcNAc Database: Q8N465
O-GlcNAcAtlas: Q8N465
Re-Glyco: Q8N465

Annotation

Keyword

3D-structure
Alternative splicing
Disease variant
FAD
Metal-binding
Mitochondrion
Oxidoreductase
Reference proteome
Transit peptide
Zinc

Gene Ontology (GO)

Displaying **all 2** entries
GO Term
mitochondrion
mitochondrial matrix

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 6** entries
GO Term
2-oxoglutarate metabolic process
response to manganese ion
response to zinc ion
malate metabolic process
protein metabolic process
response to cobalt ion

Displaying **all 3** entries
GO Term
zinc ion binding
FAD binding
(R)-2-hydroxyglutarate dehydrogenase activity

Annotation information from UniProt.

Sequence

MLPRRPLAWPAWLLRGAPGAAGSWGRPVGPLARRGCCSAPGTPEVPLTRERYPVRRLPFSTVSKQDLAAFERIVPGGVVTDPEALQAPNVDWLRTLRGCSKVLLRPRTSEEVSHILRHCHERNLAVNPQGGNTGMVGGSVPVFDEIILSTARMNRVLSFHSVSGILVCQAGCVLEELSRYVEERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLHGTVLGLEVVLADGTVLDCLTSLRKDNTGYDLKQLFIGSEGTLGIITTVSILCPPKPRAVNVAFLGCPGFAEVLQTFSTCKGMLGEILSAFEFMDAVCMQLVGRHLHLASPVQESPFYVLIETSGSNAGHDAEKLGHFLEHALGSGLVTDGTMATDQRKVKMLWALRERITEALSRDGYVYKYDLSLPVERLYDIVTDLRARLGPHAKHVVGYGHLGDGNLHLNVTAEAFSPSLLAALEPHVYEWTAGQQGSVSAEHGVGFRKRDVLGYSKPPGALQLMQQLKALLDPKGILNPYKTLPSQA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites