Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
CD209 antigen
Summary
- Lectin Name Aliases
-
- DC-SIGN
- LSECtin CRD Fc
- Monosaccharide Specificities
-
- Man
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Calcium
- Cell adhesion
- Cell membrane
- Disulfide bond
- Endocytosis
- Glycoprotein
- Host cell receptor for virus entry
- Host-virus interaction
- Innate immunity
- Mannose-binding
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| external side of plasma membrane |
| cell surface |
| extracellular region |
| cytoplasm |
| plasma membrane |
| membrane |
| host cell |
| GO Term |
|---|
| virion binding |
| mannose binding |
| carbohydrate binding |
| metal ion binding |
| virus receptor activity |
| peptide antigen binding |
Reference
| PubMed ID | Title | First Author |
|---|---|---|
| 15070901 | Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages. | Puig-Kröger A |
| 15184372 | Molecular basis of the differences in binding properties of the highly related C-type lectins DC-SIGN and L-SIGN to Lewis X trisaccharide and Schistosoma mansoni egg antigens. | Van Liempt E |
| 15166245 | C-type lectins L-SIGN and DC-SIGN capture and transmit infectious hepatitis C virus pseudotype particles. | Lozach PY |
| 15385553 | Proteomic analysis of DC-SIGN on dendritic cells detects tetramers required for ligand binding but no association with CD4. | Bernhard OK |
| 15509576 | Extended neck regions stabilize tetramers of the receptors DC-SIGN and DC-SIGNR. | Feinberg H |
| 15845541 | Selective binding of the scavenger receptor C-type lectin to Lewisx trisaccharide and related glycan ligands. | Coombs PJ |
| 15855154 | Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals. | Lozach PY |
| 16051608 | PU.1 regulates the tissue-specific expression of dendritic cell-specific intercellular adhesion molecule (ICAM)-3-grabbing nonintegrin. | Domínguez-Soto A |
| 16155001 | DC-SIGN mediates binding of dendritic cells to authentic pseudo-LewisY glycolipids of Schistosoma mansoni cercariae, the first parasite-specific ligand of DC-SIGN. | Meyer S |
| 16282604 | CEACAM1, an adhesion molecule of human granulocytes, is fucosylated by fucosyltransferase IX and interacts with DC-SIGN of dendritic cells via Lewis x residues. | Bogoevska V |
Pathway
| Pathway Name | Organism |
|---|---|
| Butyrophilin (BTN) family interactions | Homo sapiens |
| CD209 (DC-SIGN) signaling | Homo sapiens |
| RSV-host interactions | Homo sapiens |
UniLectin
| UniProt |
|---|
| Q9NNX6 |
CarboGrove
- Lectin Name
- DC-SIGN
- Common Name
- DC-SIGN
- Automated Analysis report (Top 10 high affinity glycans)
- Array Source
- Microbial
- Protein Source
- Investigator Provided
- Concentration (ug/mL)
-
G26425MP
G25559RS
G32046JJ
G48796BQ
G64541AU
G39023AU
G61491DK
G07682RX
G00052MO
G53402KW
G00051MO
