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Lectin

Summary

Lectin Name Aliases

PSA
Pisum Sativum Agglutinin

Monosaccharide Specificities

Organism

Pisum sativum (garden pea)

External Links

UniProt

P02867

LfDB

LfDB0181

UniLectin

P02867

CarboGrove

Annotation

Keyword

3D-structure
Calcium
Direct protein sequencing
Glycoprotein
Manganese
Mannose-binding
Metal-binding
Signal

Gene Ontology (GO)

Displaying **all 2** entries
GO Term
mannose binding
metal ion binding

Annotation information from UniProt.

Reference

Displaying **all 10** entries
PubMed ID	Title	First Author
3571225	Nuclear magnetic resonance investigation of cadmium 113 substituted pea and lentil lectins.	Bhattacharyya L
8530451	LEC18, a dominant Chinese hamster ovary glycosylation mutant synthesizes N-linked carbohydrates with a novel core structure.	Raju TS
14561743	Lec3 Chinese hamster ovary mutants lack UDP-N-acetylglucosamine 2-epimerase activity because of mutations in the epimerase domain of the Gne gene.	Hong Y
15044396	Carbohydrate structure and differential binding of prostate specific antigen to Maackia amurensis lectin between prostate cancer and benign prostate hypertrophy.	Ohyama C
16177264	Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.	Tabarés G
32845322	Human-specific microglial Siglec-11 transcript variant has the potential to affect polysialic acid-mediated brain functions at a distance.	Hane M
2172246	Modulation of lysosomal-associated membrane glycoproteins during retinoic acid-induced embryonal carcinoma cell differentiation.	Amos B
20008118	alpha1,2-Fucosylated and beta-N-acetylgalactosaminylated prostate-specific antigen as an efficient marker of prostatic cancer.	Fukushima K
9451032	Biotinyl-l-3-(2-naphthyl)-alanine hydrazide derivatives of N-glycans: versatile solid-phase probes for carbohydrate-recognition studies.	Leteux C
19218400	Comparative analysis of core-fucose-binding lectins from Lens culinaris and Pisum sativum using frontal affinity chromatography.	Tateno H

Lectin Frontier DataBase (LfDB)

GlyTouCan: G16276IK
V-V₀: 101.33

GlyTouCan: G33192XL
V-V₀: 79.23

GlyTouCan: G77712UR
V-V₀: 77.76

LfDB provides quantitative interaction data in terms of the affinity constants (K_a) of a series of lectins toward a panel of pyridylaminated (PA) glycans obtained by an automated frontal affinity chromatography with fluorescence detection (FAC-FD) system. Since the data are accurate and reliable, providing the absolute values of sugar-protein interactions, LfDB would be a valuable resource in the studies of glycan-related biology.

UniLectin

UniProt
P02867

CarboGrove

Lectin Name: Pisum Sativum Agglutinin
Common Name: PSA

Automated Analysis report (Top 10 high affinity glycans)

Array Source

ASNLinked

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G17689DH	41980.25	9136.94
G45359RY	36821	2234.96
G78059CC	35922.25	592.33
G80393PG	34243	1301.78
G56749GV	31925.75	597.98
G45209NR	31314.25	6208.48
G39018CC	30744.75	6563.31
G80858MF	29811.25	6524.2
G03652TR	47	12.83
G86357DX	26	6.48

GlyTouCan ID	Binding Intensity	Stdev
G17689DH	48783.25	359.78
G45209NR	40975	1392.39
G39018CC	36114.75	4725.3
G80393PG	35704.5	834.56
G80858MF	33900.75	594.87
G56749GV	32101	576.63
G45359RY	24159.5	1570.48
G78059CC	23030.5	1283.58
G03652TR	688	212.11
G86357DX	67.5	23.53

CarboGrove View

Array Source

CFG

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G82348BZ	1420.24	75.8
G56749GV	387.58	15.2
G22865RK	253.55	25.12
G09921WG	215.71	37.7
G54953LX	182	8.39
G03577YK	177.73	18.51
G45359RY	168.92	32.07
G17689DH	143.22	23.3
G18988VX	140.71	24.48
G00720XU	137.1	17.25

GlyTouCan ID	Binding Intensity	Stdev
G82348BZ	14780.32	1442.03
G56749GV	10211.5	228.9
G80393PG	8634.11	288.99
G17689DH	8435.45	200.1
G09921WG	8324.18	660.07
G22865RK	8203.14	277.49
G90130AG	7754.38	381.81
G91227VL	7592.69	138.78
G54953LX	7557.07	207.06
G45359RY	7197.59	295.27

GlyTouCan ID	Binding Intensity	Stdev
G22865RK	33294.91	896.98
G56749GV	32926.34	1678.87
G17689DH	31604.47	1291.23
G90130AG	30080.36	743.6
G91227VL	28960.94	1434.33
G80393PG	27262.31	1205.39
G45359RY	25984.73	1301.11
G54953LX	25880.08	2131.96
G03577YK	25645.48	217.77
G82348BZ	25193.51	1504.2

GlyTouCan ID	Binding Intensity	Stdev
G54953LX	44137.92	3985.43
G03577YK	42819.64	1768.31
G80313NY	42254.93	835.4
G18320HP	41832.91	1951.13
G92140GK	41814.22	1859.15
G91227VL	40383.25	4348.24
G88094DN	40092.89	1170.78
G00720XU	39775.23	2268.13
G22865RK	39019.61	2417.85
G97894QD	38865.07	255.71

CarboGrove View

Array Source

ZBiotech

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G65984FE	2824	0
G29024OJ	2080.17	0
G96896RL	1066	0
G76241TN	16.33	0
G19747OA	9.67	0
G88876JQ	8.33	0
G44747CU	8.33	0
G86053IC	8	0
G93164KQ	8	0
G86522OD	4	0

CarboGrove View

CarboGrove is populated with the results from 35 types of glycan arrays, 13 glycan families, 5 experimental methods, and 19 laboratories or companies by processing and interpreting data from various types of glycan arrays.