GlyCosmos Portal

GlyCosmos Lectins

Integrated list of Lectins, including proteins with carbohydrate binding function obtained from UniProt and lectin data from Lectin Frontier DataBase (LfDB), UniLectin and CarboGrove. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Source	Last Updated
MCAW	July 10, 2019
UniLectin	June 14, 2023
UniProt	March 3, 2025
Lectin Frontier DataBase (LfDB)	April 6, 2018
CarboGrove	June 14, 2023

Displaying entries **26 - 50** of **297** in total

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GlyCosmos Lectin	Lectin Name	UniProt ID ▲	PDB IDs	LfDB IDs	Monosaccharide Specificities	Organism	Taxonomy ID	MCAW IDs	Gene Ontology	Gene Ontology ID
GL_001178	Zymogen granule membrane protein 16	O60844	3APA 3VY6 3VY7 3VZE 3VZF 3VZG 7O3I 7O4P 7O88			Homo sapiens (human)	9606		Golgi lumen carbohydrate binding collagen-containing extracellular matrix defense response to Gram-positive bacterium extracellular space mucus layer peptidoglycan binding protein transport suppression of symbiont entry into host zymogen granule membrane	GO:0005615 GO:0005796 GO:0015031 GO:0030246 GO:0042589 GO:0042834 GO:0050830 GO:0052373 GO:0062023 GO:0070701
GL_004553	Bis(monoacylglycero)phosphate synthase CLN5	O75503	6R99			Homo sapiens (human)	9606		Golgi apparatus bis(monoacylglycero)phosphate synthase activity brain development cytosol endoplasmic reticulum extracellular exosome glycosylation hydrolase activity, acting on glycosyl bonds long-chain acyl-CoA hydrolase activity lysosomal lumen acidification lysosomal membrane lysosome organization lysosome mannose binding membrane neurogenesis neuron maturation perinuclear region of cytoplasm positive regulation of GTP binding protein catabolic process retrograde transport, endosome to Golgi signal peptide processing vacuolar lumen visual perception	GO:0005537 GO:0005764 GO:0005765 GO:0005775 GO:0005783 GO:0005794 GO:0005829 GO:0006465 GO:0007040 GO:0007042 GO:0007420 GO:0007601 GO:0016020 GO:0016798 GO:0022008 GO:0030163 GO:0042147 GO:0042551 GO:0048471 GO:0052816 GO:0070062 GO:0070085 GO:0160121 GO:1904426
GL_000169	C-type lectin domain family 3 member A	O75596				Homo sapiens (human)	9606		carbohydrate binding extracellular space ossification skeletal system development	GO:0001501 GO:0001503 GO:0005615 GO:0030246
GL_000393	Ficolin-3	O75636	2J5Z 2J60 2J64			Homo sapiens (human)	9606		antigen binding blood microparticle carbohydrate binding carbohydrate derivative binding cell surface pattern recognition receptor signaling pathway collagen trimer collagen-containing extracellular matrix complement activation, lectin pathway complement activation defense response to virus external side of plasma membrane extracellular region extracellular space metal ion binding negative regulation of RNA biosynthetic process negative regulation of viral entry into host cell positive regulation of opsonization proteolysis recognition of apoptotic cell serine-type endopeptidase complex signaling receptor binding	GO:0001867 GO:0002752 GO:0003823 GO:0005102 GO:0005576 GO:0005581 GO:0005615 GO:0006508 GO:0006956 GO:0009897 GO:0030246 GO:0043654 GO:0046597 GO:0046872 GO:0051607 GO:0062023 GO:0072562 GO:0097367 GO:1902679 GO:1903028 GO:1905370
GL_000071	Attractin	O75882				Homo sapiens (human)	9606		Golgi apparatus carbohydrate binding cerebellum development extracellular exosome extracellular space inflammatory response myelination pigmentation plasma membrane regulation of multicellular organism growth signaling receptor activity	GO:0005615 GO:0005794 GO:0005886 GO:0006954 GO:0021549 GO:0030246 GO:0038023 GO:0040014 GO:0042552 GO:0043473 GO:0070062
GL_000017	Adhesion G protein-coupled receptor L1	O94910				Homo sapiens (human)	9606		G protein-coupled receptor activity G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway axon carbohydrate binding cell adhesion molecule binding cell surface receptor signaling pathway growth cone heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules latrotoxin receptor activity membrane neuron projection plasma membrane presynaptic membrane synapse	GO:0004930 GO:0005886 GO:0007157 GO:0007166 GO:0007186 GO:0007189 GO:0016020 GO:0016524 GO:0030246 GO:0030424 GO:0030426 GO:0042734 GO:0043005 GO:0045202 GO:0050839
GL_002768	Starch-binding domain-containing protein 1	O95210				Homo sapiens (human)	9606		T-tubule cargo receptor activity endoplasmic reticulum membrane endoplasmic reticulum enzyme binding ficolin-1-rich granule membrane glycogen binding glycogen catabolic process glycophagy intracellular transport membrane perinuclear region of cytoplasm phagophore assembly site membrane plasma membrane polysaccharide binding starch binding substrate localization to autophagosome tertiary granule membrane	GO:0005783 GO:0005789 GO:0005886 GO:0005980 GO:0016020 GO:0019899 GO:0030247 GO:0030315 GO:0034045 GO:0038024 GO:0046907 GO:0048471 GO:0061723 GO:0061753 GO:0070821 GO:0101003 GO:2001069 GO:2001070
GL_001679	Laforin	O95278	4R30 4RKK			Homo sapiens (human)	9606		L-glutamate transmembrane transport Wnt signaling pathway autophagosome assembly calcium ion transport carbohydrate binding carbohydrate phosphatase activity carbohydrate phosphorylation cytoplasm cytoplasmic side of rough endoplasmic reticulum membrane cytosol dendrite dephosphorylation glial cell proliferation glycogen (starch) synthase activity glycogen binding glycogen biosynthetic process glycogen metabolic process habituation mitochondrion organization myosin phosphatase activity negative regulation of cell cycle negative regulation of dephosphorylation negative regulation of gene expression negative regulation of phosphatase activity nucleoplasm nucleus peptidyl-tyrosine dephosphorylation perikaryon phosphatase activity plasma membrane positive regulation of macroautophagy proteasome-mediated ubiquitin-dependent protein catabolic process protein dephosphorylation protein dimerization activity protein homodimerization activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity regulation of cell growth regulation of proteasomal protein catabolic process regulation of protein import into nucleus regulation of protein localization to plasma membrane regulation of protein ubiquitination starch binding	GO:0000045 GO:0001558 GO:0004373 GO:0004722 GO:0004725 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005886 GO:0005977 GO:0005978 GO:0006470 GO:0006816 GO:0007005 GO:0010629 GO:0010923 GO:0014009 GO:0015813 GO:0016055 GO:0016239 GO:0016311 GO:0016791 GO:0017018 GO:0019203 GO:0030246 GO:0030425 GO:0031396 GO:0035305 GO:0035335 GO:0042306 GO:0042803 GO:0043161 GO:0043204 GO:0045786 GO:0046835 GO:0046959 GO:0046983 GO:0061136 GO:0098556 GO:1903076 GO:2001069 GO:2001070
GL_001504	GDH/6PGL endoplasmic bifunctional protein	O95479	8EM2			Homo sapiens (human)	9606		6-phosphogluconolactonase activity NADP binding carbohydrate binding endoplasmic reticulum lumen endoplasmic reticulum glucose 1-dehydrogenase (NAD+) activity glucose 1-dehydrogenase (NADP+) activity glucose metabolic process glucose-6-phosphate dehydrogenase activity pentose-phosphate shunt, oxidative branch regulation of cortisol biosynthetic process response to alcohol response to nutrient levels	GO:0004345 GO:0005783 GO:0005788 GO:0006006 GO:0009051 GO:0017057 GO:0030246 GO:0031667 GO:0047934 GO:0047935 GO:0050661 GO:0097305 GO:2000064
GL_000020	Adhesion G protein-coupled receptor L2	O95490				Homo sapiens (human)	9606		G protein-coupled receptor activity G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway carbohydrate binding cell surface receptor signaling pathway latrotoxin receptor activity membrane plasma membrane	GO:0004930 GO:0005886 GO:0007166 GO:0007186 GO:0007189 GO:0016020 GO:0016524 GO:0030246
GL_003161	Protein phosphatase 1 regulatory subunit 3D	O95685				Homo sapiens (human)	9606		glycogen binding glycogen granule glycogen metabolic process protein phosphatase 1 binding protein phosphatase type 1 complex protein serine/threonine phosphatase activity regulation of glycogen biosynthetic process regulation of glycogen catabolic process	GO:0000164 GO:0004722 GO:0005977 GO:0005979 GO:0005981 GO:0008157 GO:0042587 GO:2001069
GL_002832	HLA class II histocompatibility antigen, DR alpha chain	P01903	1A6A 1AQD 1BX2 1D5M 1D5X 1D5Z 1D6E 1DLH 1FV1 1FYT 1H15 1HQR 1HXY 1J8H 1JWM 1JWS 1JWU 1KG0 1KLG 1KLU 1LO5 1PYW 1R5I 1SEB 1SJE 1SJH 1T5W 1T5X 1YMM 1ZGL 2FSE 2G9H 2IAM 2IAN 2ICW 2IPK 2OJE 2Q6W 2SEB 2WBJ 2XN9 3C5J 3L6F 3O6F 3PDO 3PGC 3PGD 3QXA 3QXD 3S4S 3S5L 3T0E 4AEN 4AH2 4C56 4E41 4FQX 4GBX 4H1L 4H25 4H26 4I5B 4IS6 4MCY 4MCZ 4MD0 4MD4 4MD5 4MDI 4MDJ 4OV5 4X5W 4X5X 4Y19 4Y1A 5JLZ 5LAX 5NI9 5NIG 5V4M 5V4N 6ATF 6ATI 6ATZ 6BIJ 6BIL 6BIN 6BIR 6BIV 6BIX 6BIY 6BIZ 6CPL 6CPN 6CPO 6CQJ 6CQL 6CQN 6CQQ 6CQR 6NIX 6QZA 6QZC 6QZD 6R0E 6V0Y 6V13 6V15 6V18 6V19 6V1A 7N19 7NZE 7O00 7YX9 7YXB 7Z0Q 8CMB 8CMC 8CMD 8CME 8CMF 8CMG 8CMH 8CMI 8EUQ 8PJE 8PJF 8PJG 8TBP 8TRL 8TRQ 8TRR 8VRW 9B7B			Homo sapiens (human)	9606		ER to Golgi transport vesicle membrane Golgi membrane MHC class II protein complex binding MHC class II protein complex MHC class II receptor activity T cell receptor binding adaptive immune response antigen processing and presentation of endogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide or polysaccharide antigen via MHC class II autolysosome membrane cell surface clathrin-coated endocytic vesicle membrane cognition early endosome membrane endocytic vesicle membrane extracellular exosome immune response immunological synapse late endosome membrane lumenal side of endoplasmic reticulum membrane lysosomal membrane lysosome myeloid dendritic cell antigen processing and presentation peptide antigen assembly with MHC class II protein complex peptide antigen binding plasma membrane polysaccharide binding positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation positive regulation of CD4-positive, alpha-beta T cell activation positive regulation of T cell activation positive regulation of T cell mediated cytotoxicity positive regulation of immune response positive regulation of memory T cell differentiation regulation of T-helper cell differentiation trans-Golgi network membrane transport vesicle membrane	GO:0000139 GO:0001772 GO:0001916 GO:0002250 GO:0002469 GO:0002491 GO:0002503 GO:0002504 GO:0005764 GO:0005765 GO:0005886 GO:0006955 GO:0009986 GO:0012507 GO:0019886 GO:0023026 GO:0030247 GO:0030658 GO:0030666 GO:0030669 GO:0031901 GO:0031902 GO:0032395 GO:0032588 GO:0032831 GO:0042605 GO:0042608 GO:0042613 GO:0043382 GO:0045622 GO:0050778 GO:0050870 GO:0050890 GO:0070062 GO:0098553 GO:0120281 GO:2000516
GL_002758	HLA class II histocompatibility antigen, DRB1 beta chain	P01911	1A6A 1AQD 1BX2 1D5M 1D5X 1D5Z 1D6E 1DLH 1FYT 1HXY 1J8H 1JWM 1JWS 1JWU 1KG0 1KLG 1KLU 1LO5 1PYW 1R5I 1SEB 1SJE 1SJH 1T5W 1T5X 1YMM 2FSE 2G9H 2IAM 2IAN 2ICW 2IPK 2OJE 2SEB 2WBJ 2XN9 3L6F 3O6F 3PDO 3PGC 3PGD 3QXA 3QXD 3S4S 3S5L 3T0E 4AEN 4AH2 4C56 4E41 4FQX 4GBX 4I5B 4IS6 4MCY 4MCZ 4MD0 4MD4 4MD5 4MDI 4MDJ 4OV5 4X5W 4X5X 4Y19 4Y1A 5JLZ 5LAX 5NI9 5NIG 6BIJ 6BIL 6BIN 6BIR 6BIV 6BIX 6BIY 6BIZ 6CPL 6CPN 6CPO 6CQJ 6CQL 6CQN 6CQQ 6CQR 6HBY 6NIX 6QZA 6QZC 6QZD 6R0E 6V0Y 6V13 6V15 6V18 6V19 6V1A 8PJG 8TBP 8TRL 8TRQ 8TRR 8VRW			Homo sapiens (human)	9606		CD4 receptor binding ER to Golgi transport vesicle membrane Golgi membrane MHC class II protein complex binding MHC class II protein complex MHC class II receptor activity T cell receptor binding T cell receptor signaling pathway T-helper 1 type immune response antigen processing and presentation of endogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II autolysosome membrane cell surface clathrin-coated endocytic vesicle membrane detection of bacterium endocytic vesicle membrane epidermis development external side of plasma membrane extracellular exosome extracellular space humoral immune response immune response immunological synapse inflammatory response to antigenic stimulus intermediate filament late endosome membrane lumenal side of endoplasmic reticulum membrane lysosomal membrane macrophage differentiation membrane myeloid dendritic cell antigen processing and presentation negative regulation of T cell proliferation negative regulation of inflammatory response to antigenic stimulus negative regulation of type II interferon production peptide antigen assembly with MHC class II protein complex peptide antigen binding plasma membrane polysaccharide binding positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation positive regulation of CD4-positive, alpha-beta T cell activation positive regulation of DNA-templated transcription positive regulation of ERK1 and ERK2 cascade positive regulation of MAPK cascade positive regulation of T cell activation positive regulation of T cell mediated cytotoxicity positive regulation of T cell mediated immune response to tumor cell positive regulation of canonical NF-kappaB signal transduction positive regulation of immune response positive regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation of kinase activity positive regulation of memory T cell differentiation positive regulation of monocyte differentiation positive regulation of protein phosphorylation positive regulation of viral entry into host cell protein tetramerization regulation of T-helper cell differentiation regulation of interleukin-10 production regulation of interleukin-4 production signal transduction structural constituent of cytoskeleton trans-Golgi network membrane transport vesicle membrane	GO:0000139 GO:0001772 GO:0001916 GO:0001934 GO:0002437 GO:0002469 GO:0002491 GO:0002503 GO:0002842 GO:0002862 GO:0005200 GO:0005615 GO:0005765 GO:0005882 GO:0005886 GO:0006955 GO:0006959 GO:0007165 GO:0008544 GO:0009897 GO:0009986 GO:0012507 GO:0016020 GO:0016045 GO:0019886 GO:0023026 GO:0030225 GO:0030247 GO:0030658 GO:0030666 GO:0030669 GO:0031902 GO:0032395 GO:0032588 GO:0032653 GO:0032673 GO:0032689 GO:0032831 GO:0033674 GO:0035774 GO:0042088 GO:0042130 GO:0042605 GO:0042608 GO:0042609 GO:0042613 GO:0043123 GO:0043382 GO:0043410 GO:0045622 GO:0045657 GO:0045893 GO:0046598 GO:0050778 GO:0050852 GO:0050870 GO:0051262 GO:0070062 GO:0070374 GO:0098553 GO:0120281 GO:2000516
GL_002302	C-reactive protein	P02741	1B09 1GNH 1LJ7 3L2Y 3PVN 3PVO 7PK9 7PKB 7PKD 7PKE 7PKF 7PKG 7PKH 7TBA 8WV4 8WV5			Homo sapiens (human)	9606		acute-phase response calcium ion binding choline binding complement component C1q complex binding defense response to Gram-positive bacterium extracellular region extracellular space identical protein binding inflammatory response innate immune response low-density lipoprotein particle binding low-density lipoprotein particle receptor binding negative regulation of lipid storage negative regulation of macrophage derived foam cell differentiation negative regulation of mononuclear cell proliferation opsonization positive regulation of gene expression positive regulation of superoxide anion generation regulation of interleukin-8 production vasoconstriction	GO:0001849 GO:0005509 GO:0005576 GO:0005615 GO:0006953 GO:0006954 GO:0008228 GO:0010628 GO:0010745 GO:0010888 GO:0030169 GO:0032677 GO:0032930 GO:0032945 GO:0033265 GO:0042310 GO:0042802 GO:0045087 GO:0050750 GO:0050830
GL_001101	Serum amyloid P-component	P02743	1GYK 1LGN 1SAC 2A3W 2A3X 2A3Y 2W08 3D5O 3KQR 4AVS 4AVT 4AVV 4AYU			Homo sapiens (human)	9606		acute-phase response blood microparticle calcium ion binding carbohydrate binding chaperone-mediated protein complex assembly collagen-containing extracellular matrix complement component C1q complex binding extracellular exosome extracellular region extracellular space identical protein binding innate immune response negative regulation by host of viral exo-alpha-sialidase activity negative regulation by host of viral glycoprotein metabolic process negative regulation of acute inflammatory response negative regulation of exo-alpha-sialidase activity negative regulation of glycoprotein metabolic process negative regulation of monocyte differentiation negative regulation of viral entry into host cell negative regulation of viral process negative regulation of wound healing nucleus protein folding unfolded protein binding virion binding	GO:0001849 GO:0002674 GO:0005509 GO:0005576 GO:0005615 GO:0005634 GO:0006457 GO:0006953 GO:0030246 GO:0042802 GO:0044869 GO:0044871 GO:0045087 GO:0045656 GO:0046597 GO:0046790 GO:0048525 GO:0051082 GO:0051131 GO:0061045 GO:0062023 GO:0070062 GO:0072562 GO:1903016 GO:1903019
GL_001781	Protein AMBP	P02760	1BIK 3QKG 4ES7 4U30 6EJ7 6EJ8 6EJ9 6EJA 6EJB 6EJC 6EJD			Homo sapiens (human)	9606		IgA binding blood microparticle calcium channel inhibitor activity calcium oxalate binding carbohydrate binding cell adhesion cell surface collagen-containing extracellular matrix cytosol endoplasmic reticulum extracellular exosome extracellular region extracellular space female pregnancy heme binding heme catabolic process mitochondrial inner membrane negative regulation of JNK cascade negative regulation of immune response negative regulation of peptidase activity nuclear membrane oxidoreductase activity plasma membrane protein homodimerization activity serine-type endopeptidase inhibitor activity	GO:0004867 GO:0005576 GO:0005615 GO:0005743 GO:0005783 GO:0005829 GO:0005886 GO:0007155 GO:0007565 GO:0009986 GO:0010466 GO:0016491 GO:0019855 GO:0019862 GO:0020037 GO:0030246 GO:0031965 GO:0042167 GO:0042803 GO:0046329 GO:0046904 GO:0050777 GO:0062023 GO:0070062 GO:0072562
GL_002853	Vitronectin	P04004	1OC0 1S4G 1SSU 2JQ8 3BT1 3BT2 4K24 6O5E 7RJ9			Homo sapiens (human)	9606		Golgi lumen alphav-beta3 integrin-vitronectin complex basement membrane blood microparticle cell adhesion mediated by integrin cell adhesion cell migration cell-matrix adhesion collagen binding collagen-containing extracellular matrix endodermal cell differentiation endoplasmic reticulum extracellular exosome extracellular matrix binding extracellular matrix organization extracellular matrix structural constituent extracellular region extracellular space heparin binding identical protein binding immune response integrin binding intracellular membrane-bounded organelle liver regeneration negative regulation of blood coagulation negative regulation of endopeptidase activity negative regulation of fibrinolysis oligodendrocyte differentiation peptidase inhibitor complex polysaccharide binding positive regulation of cell-substrate adhesion positive regulation of peptidyl-tyrosine phosphorylation positive regulation of protein binding positive regulation of receptor-mediated endocytosis positive regulation of smooth muscle cell migration positive regulation of vascular endothelial growth factor receptor signaling pathway positive regulation of wound healing protein complex involved in cell-matrix adhesion protein polymerization regulation of cell adhesion rough endoplasmic reticulum lumen scavenger receptor activity smooth muscle cell-matrix adhesion	GO:0005044 GO:0005178 GO:0005201 GO:0005518 GO:0005576 GO:0005604 GO:0005615 GO:0005783 GO:0005796 GO:0006955 GO:0007155 GO:0007160 GO:0008201 GO:0010811 GO:0010951 GO:0014911 GO:0016477 GO:0030155 GO:0030195 GO:0030198 GO:0030247 GO:0030949 GO:0032092 GO:0033627 GO:0035987 GO:0042802 GO:0043231 GO:0048237 GO:0048260 GO:0048709 GO:0050731 GO:0050840 GO:0051258 GO:0051918 GO:0061302 GO:0062023 GO:0070062 GO:0071062 GO:0072562 GO:0090303 GO:0097421 GO:0098637 GO:1904090
GL_004526	Fructose-bisphosphate aldolase A	P04075	1ALD 2ALD 4ALD 5KY6 6XMH 6XML 6XMM 6XMO			Homo sapiens (human)	9606		ATP biosynthetic process I band M band RNA binding actin binding actin cytoskeleton actin filament organization binding of sperm to zona pellucida cadherin binding cytoskeletal protein binding cytosol extracellular exosome extracellular region extracellular space ficolin-1-rich granule lumen fructose 1,6-bisphosphate metabolic process fructose binding fructose metabolic process fructose-bisphosphate aldolase activity glycolytic process identical protein binding membrane muscle cell cellular homeostasis nucleus platelet alpha granule lumen protein homotetramerization regulation of cell shape secretory granule lumen sperm head striated muscle contraction tertiary granule lumen tubulin binding	GO:0003723 GO:0003779 GO:0004332 GO:0005576 GO:0005615 GO:0005634 GO:0005829 GO:0006000 GO:0006096 GO:0006754 GO:0006941 GO:0007015 GO:0007339 GO:0008092 GO:0008360 GO:0015629 GO:0015631 GO:0016020 GO:0030388 GO:0031093 GO:0031430 GO:0031674 GO:0034774 GO:0042802 GO:0045296 GO:0046716 GO:0051289 GO:0061827 GO:0070061 GO:0070062 GO:1904724 GO:1904813
GL_002318	Trefoil factor 1	P04155	1HI7 1PS2 6V1D			Homo sapiens (human)	9606		carbohydrate metabolic process cell differentiation cell population proliferation extracellular region extracellular space growth factor activity maintenance of gastrointestinal epithelium negative regulation of cell population proliferation response to immobilization stress response to iron ion response to peptide hormone	GO:0005576 GO:0005615 GO:0005975 GO:0008083 GO:0008283 GO:0008285 GO:0010039 GO:0030154 GO:0030277 GO:0035902 GO:0043434
GL_001669	Keratin, type II cytoskeletal 1	P04264	4ZRY 6E2J 6UUI			Homo sapiens (human)	9606		blood microparticle carbohydrate binding collagen-containing extracellular matrix complement activation, lectin pathway cornified envelope cytoplasm cytoskeleton cytosol establishment of skin barrier extracellular exosome extracellular region extracellular space fibrinolysis ficolin-1-rich granule lumen intermediate filament organization keratin filament keratinization membrane negative regulation of inflammatory response nucleus peptide cross-linking protein heterodimerization activity protein heterotetramerization regulation of angiogenesis response to oxidative stress signaling receptor activity structural constituent of skin epidermis	GO:0001533 GO:0001867 GO:0005576 GO:0005615 GO:0005634 GO:0005737 GO:0005829 GO:0005856 GO:0006979 GO:0016020 GO:0018149 GO:0030246 GO:0030280 GO:0031424 GO:0038023 GO:0042730 GO:0045095 GO:0045109 GO:0045765 GO:0046982 GO:0050728 GO:0051290 GO:0061436 GO:0062023 GO:0070062 GO:0072562 GO:1904813
GL_004522	Fructose-bisphosphate aldolase B	P05062	1QO5 1XDL 1XDM 8D44			Homo sapiens (human)	9606		ATPase binding NADH oxidation centriolar satellite cytoskeletal protein binding cytosol extracellular exosome fructose 1,6-bisphosphate metabolic process fructose binding fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate fructose metabolic process fructose-1-phosphate aldolase activity fructose-bisphosphate aldolase activity gluconeogenesis glycolytic process identical protein binding microtubule organizing center molecular adaptor activity negative regulation of pentose-phosphate shunt positive regulation of ATP-dependent activity vacuolar proton-transporting V-type ATPase complex assembly	GO:0004332 GO:0005815 GO:0005829 GO:0006000 GO:0006094 GO:0006096 GO:0006116 GO:0008092 GO:0030388 GO:0032781 GO:0034451 GO:0042802 GO:0051117 GO:0060090 GO:0061609 GO:0061624 GO:0070061 GO:0070062 GO:0070072 GO:1905856
GL_000487	Galectin-2 Aliases: Galectin-2 (Human)	P05162	1HLC 5DG1 5DG2 5EWS	LfDB0055	Gal	Homo sapiens (human)	9606	5110	T cell homeostasis carbohydrate binding cell-cell adhesion galactoside binding galectin complex positive regulation of apoptotic process positive regulation of inflammatory response	GO:0016936 GO:0030246 GO:0043029 GO:0043065 GO:0050729 GO:0098609 GO:1990724
GL_002323	Intercellular adhesion molecule 1	P05362	1D3E 1D3I 1D3L 1IAM 1IC1 1MQ8 1P53 1Z7Z 2OZ4 3TCX 5MZA 6EIT 6S8U 7BG7			Homo sapiens (human)	9606		T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell T cell antigen processing and presentation T cell extravasation adhesion of symbiont to host cell adhesion mediated by integrin cell adhesion cell surface cellular response to amyloid-beta cellular response to glucose stimulus cellular response to leukemia inhibitory factor collagen-containing extracellular matrix establishment of endothelial barrier external side of plasma membrane extracellular exosome extracellular space focal adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules immunological synapse integrin binding leukocyte cell-cell adhesion leukocyte migration membrane raft membrane to membrane docking membrane negative regulation of endothelial cell apoptotic process negative regulation of extrinsic apoptotic signaling pathway via death domain receptors plasma membrane positive regulation of ERK1 and ERK2 cascade positive regulation of cellular extravasation receptor-mediated virion attachment to host cell regulation of leukocyte mediated cytotoxicity regulation of ruffle assembly signaling receptor activity transmembrane signaling receptor activity virus receptor activity	GO:0001618 GO:0001772 GO:0001910 GO:0002291 GO:0002457 GO:0002693 GO:0004888 GO:0005178 GO:0005615 GO:0005886 GO:0005925 GO:0007155 GO:0007157 GO:0007159 GO:0009897 GO:0009986 GO:0016020 GO:0022614 GO:0033627 GO:0038023 GO:0044406 GO:0045121 GO:0046813 GO:0050900 GO:0061028 GO:0062023 GO:0070062 GO:0070374 GO:0071333 GO:0072683 GO:1900027 GO:1902042 GO:1904646 GO:1990830 GO:2000352
GL_002041	Lithostathine-1-alpha	P05451	1LIT 1QDD			Homo sapiens (human)	9606		antimicrobial humoral immune response mediated by antimicrobial peptide extracellular exosome extracellular space growth factor activity molecular function inhibitor activity oligosaccharide binding peptidoglycan binding positive regulation of cell population proliferation response to peptide hormone signaling receptor activity	GO:0005615 GO:0008083 GO:0008284 GO:0038023 GO:0042834 GO:0043434 GO:0061844 GO:0070062 GO:0070492 GO:0140678
GL_001143	Tetranectin	P05452	1HTN 1RJH 1TN3 3L9J			Homo sapiens (human)	9606		bone mineralization calcium ion binding carbohydrate binding collagen-containing extracellular matrix cytoplasm extracellular exosome extracellular region extracellular space granular component heparin binding kringle domain binding ossification platelet dense granule lumen positive regulation of plasminogen activation	GO:0001503 GO:0001652 GO:0005509 GO:0005576 GO:0005615 GO:0005737 GO:0008201 GO:0010756 GO:0030246 GO:0030282 GO:0031089 GO:0036143 GO:0062023 GO:0070062

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