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HLA class II histocompatibility antigen, DRB1 beta chain

Summary

Organism: Homo sapiens (human)

External Links

UniProt: P01911

Annotation

Keyword

3D-structure
Cell membrane
Cytoplasmic vesicle
Direct protein sequencing
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Isopeptide bond
Lysosome
MHC II
Reference proteome
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 36 in total

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GO Term
positive regulation of DNA-templated transcription
immune response
humoral immune response
signal transduction
epidermis development
macrophage differentiation
negative regulation of type II interferon production
positive regulation of kinase activity
negative regulation of T cell proliferation
positive regulation of memory T cell differentiation

Displaying entries **1 - 10** of 19 in total

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GO Term
Golgi membrane
external side of plasma membrane
cell surface
extracellular space
intermediate filament
plasma membrane
membrane
MHC class II protein complex
lysosomal membrane
ER to Golgi transport vesicle membrane

Displaying **all 7** entries
GO Term
structural constituent of cytoskeleton
polysaccharide binding
peptide antigen binding
CD4 receptor binding
T cell receptor binding
MHC class II protein complex binding
MHC class II receptor activity

Annotation information from UniProt.

Pathway

Displaying **all 7** entries
Pathway Name	Organism
Downstream TCR signaling	Homo sapiens
Generation of second messenger molecules	Homo sapiens
Interferon gamma signaling	Homo sapiens
MHC class II antigen presentation	Homo sapiens
PD-1 signaling	Homo sapiens
Phosphorylation of CD3 and TCR zeta chains	Homo sapiens
Translocation of ZAP-70 to Immunological synapse	Homo sapiens

MCAW-DB (Glycan Recognition Profile)

MCAW-DB is a database whereby users can view the multiple alignment analysis results obtained from the MCAW tool, which can computationally find common glycan substructures among a group of glycan structures. The data in MCAW-DB are analysis results of glycan array experiments; those glycans having higher binding affinity to glycan binding proteins (GBPs) have been analyzed and can be viewed as “glycan recognition profiles”. Currently, this database provides published analysis results of glycan array data from the Consortium for Functional Glycomics (CFG).