GlyCosmos Portal

GlyCosmos Lectins

Integrated list of Lectins, including proteins with carbohydrate binding function obtained from UniProt and lectin data from Lectin Frontier DataBase (LfDB), UniLectin and CarboGrove. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Source	Last Updated
MCAW	July 10, 2019
UniLectin	June 14, 2023
UniProt	June 6, 2024
Lectin Frontier DataBase (LfDB)	April 6, 2018
CarboGrove	June 14, 2023

Displaying entries **76 - 100** of **298** in total

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GlyCosmos Lectin	Lectin Name	UniProt ID	PDB IDs	Organism	Taxonomy ID	Gene Ontology ▲	Gene Ontology ID
GL_000927	Polypeptide N-acetylgalactosaminyltransferase 6	Q8NCL4		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation via threonine protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0018243 GO:0030246 GO:0046872 GO:0048471
GL_000897	Polypeptide N-acetylgalactosaminyltransferase 13	Q8IUC8		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation via serine protein O-linked glycosylation via threonine protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0018242 GO:0018243 GO:0030246 GO:0046872
GL_000902	Polypeptide N-acetylgalactosaminyltransferase 15	Q8N3T1		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation transport vesicle	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030133 GO:0030246 GO:0046872
GL_000900	Polypeptide N-acetylgalactosaminyltransferase 14	Q96FL9		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000931	Polypeptide N-acetylgalactosaminyltransferase 9	Q9HCQ5		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000895	Polypeptide N-acetylgalactosaminyltransferase 12	Q8IXK2	6PXU	Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000957	Probable polypeptide N-acetylgalactosaminyltransferase 8	Q9NY28		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000888	Polypeptide N-acetylgalactosaminyltransferase 10	Q86SR1	2D7I 2D7R	Homo sapiens (human)	9606	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_000904	Polypeptide N-acetylgalactosaminyltransferase 16	Q8N428		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation via serine protein O-linked glycosylation via threonine protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0018242 GO:0018243 GO:0030246 GO:0046872
GL_000933	Polypeptide N-acetylgalactosaminyltransferase-like 6	Q49A17		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation via threonine protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0018243 GO:0030246 GO:0046872
GL_000908	Polypeptide N-acetylgalactosaminyltransferase 18	Q6P9A2		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872
GL_000907	Polypeptide N-acetylgalactosaminyltransferase 17	Q6IS24		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872
GL_005175	Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3	O60568	6FXK 6FXM 6FXR 6FXT 6FXX 6FXY 6TE3 6TEC 6TES 6TEU 6TEX 6TEZ 6WFV 8ONE	Homo sapiens (human)	9606	Golgi apparatus L-ascorbic acid binding basement membrane assembly collagen fibril organization collagen metabolic process collagen-containing extracellular matrix endoplasmic reticulum lumen endoplasmic reticulum membrane endoplasmic reticulum endothelial cell morphogenesis epidermis morphogenesis extracellular exosome extracellular space hydroxylysine biosynthetic process in utero embryonic development iron ion binding lung morphogenesis metal ion binding neural tube development peptidyl-lysine hydroxylation procollagen galactosyltransferase activity procollagen glucosyltransferase activity procollagen-lysine 5-dioxygenase activity protein O-linked glycosylation protein localization rough endoplasmic reticulum small molecule binding trans-Golgi network vasodilation	GO:0001701 GO:0001886 GO:0005506 GO:0005615 GO:0005783 GO:0005788 GO:0005789 GO:0005791 GO:0005794 GO:0005802 GO:0006493 GO:0008104 GO:0008475 GO:0017185 GO:0021915 GO:0030199 GO:0031418 GO:0032963 GO:0033823 GO:0036094 GO:0042311 GO:0046872 GO:0046947 GO:0048730 GO:0050211 GO:0060425 GO:0062023 GO:0070062 GO:0070831
GL_005093	Prolyl 3-hydroxylase 2	Q8IVL5		Homo sapiens (human)	9606	Golgi apparatus L-ascorbic acid binding basement membrane collagen metabolic process cytosol endoplasmic reticulum lumen endoplasmic reticulum intracellular membrane-bounded organelle iron ion binding negative regulation of cell population proliferation nucleoplasm peptidyl-proline hydroxylation procollagen-proline 3-dioxygenase activity sarcoplasmic reticulum	GO:0005506 GO:0005604 GO:0005654 GO:0005783 GO:0005788 GO:0005794 GO:0005829 GO:0008285 GO:0016529 GO:0019511 GO:0019797 GO:0031418 GO:0032963 GO:0043231
GL_001725	Neutral alpha-glucosidase AB	Q14697	8D43 8EMR	Homo sapiens (human)	9606	Golgi apparatus N-glycan processing RNA binding alpha-glucosidase activity carbohydrate binding carbohydrate metabolic process endoplasmic reticulum lumen extracellular exosome glucan 1,3-alpha-glucosidase activity glucosidase II complex intracellular membrane-bounded organelle melanosome membrane	GO:0003723 GO:0005788 GO:0005794 GO:0005975 GO:0006491 GO:0016020 GO:0017177 GO:0030246 GO:0033919 GO:0042470 GO:0043231 GO:0070062 GO:0090599
GL_002325	T-cell surface antigen CD2	P06729	1CDB 1GYA 1HNF 1L2Z 1QA9 2J6O 2J7I	Homo sapiens (human)	9606	Golgi apparatus T cell activation apoptotic process cell surface receptor signaling pathway cell surface cell-cell adhesion cell-cell junction cytoplasmic side of plasma membrane external side of plasma membrane extracellular region heterotypic cell-cell adhesion identical protein binding membrane raft polarization natural killer cell activation natural killer cell mediated cytotoxicity nucleoplasm plasma membrane positive regulation of interleukin-8 production positive regulation of myeloid dendritic cell activation positive regulation of tumor necrosis factor production positive regulation of type II interferon production protein self-association protein-containing complex receptor tyrosine kinase binding regulation of T cell differentiation signaling receptor activity signaling receptor binding	GO:0001766 GO:0005102 GO:0005576 GO:0005654 GO:0005794 GO:0005886 GO:0005911 GO:0006915 GO:0007166 GO:0009897 GO:0009898 GO:0009986 GO:0030101 GO:0030887 GO:0030971 GO:0032729 GO:0032757 GO:0032760 GO:0032991 GO:0034113 GO:0038023 GO:0042110 GO:0042267 GO:0042802 GO:0043621 GO:0045580 GO:0098609
GL_001840	Sucrase-isomaltase, intestinal	P14410	3LPO 3LPP	Homo sapiens (human)	9606	Golgi apparatus alpha-1,4-glucosidase activity apical plasma membrane brush border carbohydrate binding extracellular exosome oligo-1,6-glucosidase activity plasma membrane polysaccharide digestion sucrose alpha-glucosidase activity sucrose catabolic process	GO:0004558 GO:0004574 GO:0004575 GO:0005794 GO:0005886 GO:0005903 GO:0005987 GO:0016324 GO:0030246 GO:0044245 GO:0070062
GL_004553	Bis(monoacylglycero)phosphate synthase CLN5	O75503	6R99	Homo sapiens (human)	9606	Golgi apparatus bis(monoacylglycero)phosphate synthase activity brain development cytosol endoplasmic reticulum extracellular exosome glycosylation hydrolase activity, acting on glycosyl bonds long-chain acyl-CoA hydrolase activity lysosomal lumen acidification lysosomal membrane lysosome organization lysosome mannose binding membrane neurogenesis neuron maturation perinuclear region of cytoplasm positive regulation of GTP binding protein catabolic process retrograde transport, endosome to Golgi signal peptide processing vacuolar lumen visual perception	GO:0005537 GO:0005764 GO:0005765 GO:0005775 GO:0005783 GO:0005794 GO:0005829 GO:0006465 GO:0007040 GO:0007042 GO:0007420 GO:0007601 GO:0016020 GO:0016798 GO:0022008 GO:0030163 GO:0042147 GO:0042551 GO:0048471 GO:0052816 GO:0070062 GO:0070085 GO:0160121 GO:1904426
GL_000782	Myeloid cell surface antigen CD33	P20138	5IHB 5J06 5J0B 6D48 6D49 6D4A 6TL8 7AW6	Homo sapiens (human)	9606	Golgi apparatus carbohydrate binding cell adhesion cell surface cell-cell adhesion cell-cell signaling external side of plasma membrane immune response-inhibiting signal transduction negative regulation of calcium ion transport negative regulation of cell population proliferation negative regulation of interleukin-1 beta production negative regulation of interleukin-8 production negative regulation of monocyte activation negative regulation of tumor necrosis factor production nucleoplasm peroxisome plasma membrane positive regulation of protein secretion positive regulation of protein tyrosine phosphatase activity protein phosphatase binding sialic acid binding signal transduction signaling receptor activity specific granule membrane tertiary granule membrane	GO:0002765 GO:0005654 GO:0005777 GO:0005794 GO:0005886 GO:0007155 GO:0007165 GO:0007267 GO:0008285 GO:0009897 GO:0009986 GO:0019903 GO:0030246 GO:0032691 GO:0032717 GO:0032720 GO:0033691 GO:0035579 GO:0038023 GO:0050714 GO:0051926 GO:0070821 GO:0098609 GO:0150102 GO:1903615
GL_000071	Attractin	O75882		Homo sapiens (human)	9606	Golgi apparatus carbohydrate binding cerebellum development extracellular exosome extracellular space inflammatory response myelination pigmentation plasma membrane regulation of multicellular organism growth signaling receptor activity	GO:0005615 GO:0005794 GO:0005886 GO:0006954 GO:0021549 GO:0030246 GO:0038023 GO:0040014 GO:0042552 GO:0043473 GO:0070062
GL_000975	Protein FAM3C	Q92520	5LC2	Homo sapiens (human)	9606	Golgi apparatus carbohydrate binding cytokine activity extracellular exosome extracellular region extracellular space platelet dense granule lumen	GO:0005125 GO:0005576 GO:0005615 GO:0005794 GO:0030246 GO:0031089 GO:0070062
GL_004621	Collectin-10	Q9Y6Z7		Homo sapiens (human)	9606	Golgi apparatus cell surface pattern recognition receptor signaling pathway chemoattractant activity collagen trimer complement activation, lectin pathway cranial skeletal system development cytoplasm external side of plasma membrane extracellular region extracellular space mannose binding multivesicular body positive regulation of opsonization proteolysis serine-type endopeptidase complex	GO:0001867 GO:0002752 GO:0005537 GO:0005576 GO:0005581 GO:0005615 GO:0005737 GO:0005771 GO:0005794 GO:0006508 GO:0009897 GO:0042056 GO:1903028 GO:1904888 GO:1905370
GL_001993	C-type lectin domain family 18 member C	Q8NCF0		Homo sapiens (human)	9606	Golgi apparatus endoplasmic reticulum endosome extracellular space polysaccharide binding	GO:0005615 GO:0005768 GO:0005783 GO:0005794 GO:0030247
GL_001991	C-type lectin domain family 18 member A	A5D8T8		Homo sapiens (human)	9606	Golgi apparatus endoplasmic reticulum endosome extracellular space polysaccharide binding	GO:0005615 GO:0005768 GO:0005783 GO:0005794 GO:0030247
GL_001992	C-type lectin domain family 18 member B	Q6UXF7		Homo sapiens (human)	9606	Golgi apparatus endosome extracellular space polysaccharide binding sarcoplasmic reticulum	GO:0005615 GO:0005768 GO:0005794 GO:0016529 GO:0030247

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