GlyCosmos Portal

GlyCosmos Lectins

Integrated list of Lectins, including proteins with carbohydrate binding function obtained from UniProt and lectin data from Lectin Frontier DataBase (LfDB), UniLectin and CarboGrove. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Source	Last Updated
MCAW	July 10, 2019
UniLectin	June 14, 2023
UniProt	June 6, 2024
Lectin Frontier DataBase (LfDB)	April 6, 2018
CarboGrove	June 14, 2023

Displaying entries **1 - 25** of **298** in total

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GlyCosmos Lectin	Lectin Name	UniProt ID	PDB IDs	LfDB IDs	Monosaccharide Specificities ▲	Organism	Taxonomy ID	MCAW IDs	Gene Ontology	Gene Ontology ID
GL_000491	Galectin-3 Aliases: Gal3 Galectin-3 (Human)	P17931	1A3K 1KJL 1KJR 2NMN 2NMO 2NN8 2XG3 3AYA 3AYC 3AYD 3AYE 3T1L 3T1M 3ZSJ 3ZSK 3ZSL 3ZSM 4BLI 4BLJ 4BM8 4JC1 4JCK 4LBJ 4LBK 4LBL 4LBM 4LBN 4LBO 4R9A 4R9B 4R9C 4R9D 4RL7 4XBN 5E88 5E89 5E8A 5EXO 5H9P 5H9R 5IUQ 5NF7 5NF9 5NFA 5NFB 5NFC 5OAX 5ODY 6B8K 6EOG 6EOL 6EXY 6EYM 6F2Q 6F6Y 6FK2 6FOF 6G0V 6H64 6I74 6I75 6I76 6I77 6I78 6KXA 6KXB 6Q0Q 6Q17 6QGE 6QGF 6QLN 6QLO 6QLP 6QLQ 6QLR 6QLS 6QLT 6QLU 6RHL 6RHM 6RZF 6RZG 6RZH 6RZI 6RZJ 6RZK 6RZL 6RZM 6TF6 6TF7 6Y4C 6Y78 6ZVF 7BE3 7CXA 7DF5 7RDO 7RDP 7RGX 7RGY 7RGZ 7RH0 7RH1 7RH3 7RH4 7XFA 7ZQX 8BZ3 8OJI 8OJK 8OJM 8OJO 8PBF 8PF9 8PFF 8PPN	LfDB0056 LfDB0065	Gal	Homo sapiens (human)	9606	103 104 106 107 108 115 116 5108	IgE binding RNA binding RNA splicing carbohydrate binding cell surface chemoattractant activity collagen-containing extracellular matrix cytoplasm cytosol disaccharide binding eosinophil chemotaxis epithelial cell differentiation extracellular exosome extracellular region extracellular space ficolin-1-rich granule membrane immunological synapse innate immune response laminin binding mRNA processing macrophage chemotaxis membrane mitochondrial inner membrane molecular condensate scaffold activity monocyte chemotaxis mononuclear cell migration negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell negative regulation of T cell receptor signaling pathway negative regulation of endocytosis negative regulation of extrinsic apoptotic signaling pathway negative regulation of immunological synapse formation negative regulation of protein tyrosine phosphatase activity neutrophil chemotaxis nucleoplasm nucleus plasma membrane positive chemotaxis positive regulation of calcium ion import positive regulation of mononuclear cell migration positive regulation of protein localization to plasma membrane positive regulation of protein-containing complex assembly protein phosphatase binding protein phosphatase inhibitor activity regulation of T cell apoptotic process regulation of T cell proliferation regulation of extrinsic apoptotic signaling pathway via death domain receptors secretory granule membrane spliceosomal complex	GO:0001772 GO:0002548 GO:0003723 GO:0004864 GO:0005576 GO:0005615 GO:0005634 GO:0005654 GO:0005681 GO:0005737 GO:0005743 GO:0005829 GO:0005886 GO:0006397 GO:0008380 GO:0009986 GO:0016020 GO:0019863 GO:0019903 GO:0030246 GO:0030593 GO:0030667 GO:0030855 GO:0031334 GO:0042056 GO:0042129 GO:0043236 GO:0045087 GO:0045806 GO:0048030 GO:0048245 GO:0048246 GO:0050860 GO:0050918 GO:0062023 GO:0070062 GO:0070232 GO:0071674 GO:0071677 GO:0090280 GO:0101003 GO:0140693 GO:1902041 GO:1903078 GO:1903614 GO:2000521 GO:2001189 GO:2001237
GL_000487	Galectin-2 Aliases: Galectin-2 (Human)	P05162	1HLC 5DG1 5DG2 5EWS	LfDB0055	Gal	Homo sapiens (human)	9606	5110	T cell homeostasis carbohydrate binding cell-cell adhesion galactoside binding galectin complex positive regulation of apoptotic process positive regulation of inflammatory response	GO:0016936 GO:0030246 GO:0043029 GO:0043065 GO:0050729 GO:0098609 GO:1990724
GL_000507	Galectin-7 Aliases: Galectin-7 (Human)	P47929	1BKZ 2GAL 3GAL 3ZXE 3ZXF 4GAL 4UW3 4UW4 4UW5 4UW6 4XBQ 4Y26 5GAL 5H9Q 5H9S 6VTO 6VTP 6VTQ 6VTR 6VTS 7N4O 7N57 7N6C 7N8D 7N8G 7N96 7RDG 7TKW 7TKX 7TKY 7TKZ 7TRN 7TRO 7XAC 7XBL	LfDB0058	Gal	Homo sapiens (human)	9606	1461 1702 1703 1710 5107	apoptotic process carbohydrate binding cytoplasm extracellular exosome extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules nucleus	GO:0005615 GO:0005634 GO:0005737 GO:0006915 GO:0007157 GO:0030246 GO:0070062
GL_001382	CD209 antigen Aliases: DC-SIGN LSECtin CRD Fc	Q9NNX6	1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6 6GHV 7NL6 7NL7	LfDB0019 LfDB0277	Man	Homo sapiens (human)	9606		B cell adhesion adaptive immune response antigen processing and presentation carbohydrate binding cell surface cell-cell recognition cytoplasm endocytosis external side of plasma membrane extracellular region fucose binding heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules host cell immune response innate immune response intracellular signal transduction intracellular transport of virus leukocyte cell-cell adhesion mannose binding membrane metal ion binding peptide antigen binding peptide antigen transport plasma membrane positive regulation of T cell proliferation positive regulation of viral life cycle regulation of T cell proliferation viral entry into host cell viral genome replication virion attachment to host cell virion binding virus receptor activity	GO:0001618 GO:0002250 GO:0005537 GO:0005576 GO:0005737 GO:0005886 GO:0006897 GO:0006955 GO:0007157 GO:0007159 GO:0009897 GO:0009986 GO:0009988 GO:0016020 GO:0019062 GO:0019079 GO:0019882 GO:0030246 GO:0035556 GO:0042102 GO:0042129 GO:0042605 GO:0042806 GO:0043657 GO:0045087 GO:0046718 GO:0046790 GO:0046872 GO:0046968 GO:0075733 GO:0097323 GO:1903902
GL_001891	Zona pellucida sperm-binding protein 3	P21754				Homo sapiens (human)	9606		acrosin binding binding of sperm to zona pellucida blastocyst formation carbohydrate binding collagen-containing extracellular matrix egg coat formation egg coat extracellular matrix structural constituent extracellular matrix extracellular region extracellular space humoral immune response mediated by circulating immunoglobulin identical protein binding negative regulation of DNA-templated transcription negative regulation of binding of sperm to zona pellucida oocyte development plasma membrane positive regulation of DNA-templated transcription positive regulation of T cell proliferation positive regulation of acrosomal vesicle exocytosis positive regulation of acrosome reaction positive regulation of antral ovarian follicle growth positive regulation of humoral immune response positive regulation of inflammatory response positive regulation of interleukin-4 production positive regulation of leukocyte migration positive regulation of ovarian follicle development positive regulation of type II interferon production positive regulation of type IV hypersensitivity receptor ligand activity structural constituent of egg coat	GO:0001809 GO:0001825 GO:0002455 GO:0002687 GO:0002922 GO:0005201 GO:0005576 GO:0005615 GO:0005886 GO:0007339 GO:0030246 GO:0031012 GO:0032190 GO:0032729 GO:0032753 GO:0035803 GO:0035804 GO:0035805 GO:0042102 GO:0042802 GO:0045892 GO:0045893 GO:0048018 GO:0048599 GO:0050729 GO:0062023 GO:2000344 GO:2000360 GO:2000368 GO:2000386 GO:2000388
GL_003205	Glycerophosphocholine phosphodiesterase GPCPD1	Q9NPB8	2Z0B			Homo sapiens (human)	9606		cytosol glycerophosphocholine phosphodiesterase activity glycerophospholipid catabolic process skeletal muscle tissue development starch binding	GO:0005829 GO:0007519 GO:0046475 GO:0047389 GO:2001070
GL_005235	Prolyl 3-hydroxylase 3	Q8IVL6				Homo sapiens (human)	9606		L-ascorbic acid binding catalytic complex collagen biosynthetic process collagen metabolic process endoplasmic reticulum iron ion binding negative regulation of cell population proliferation peptidyl-lysine hydroxylation procollagen-proline 3-dioxygenase activity	GO:0005506 GO:0005783 GO:0008285 GO:0017185 GO:0019797 GO:0031418 GO:0032963 GO:0032964 GO:1902494
GL_000272	Calreticulin	P27797	2CLR 3DOW 3POS 3POW 5LK5 5V90 6ENY 7QPD 8TZO 8TZR			Homo sapiens (human)	9606		DNA binding ERAD pathway MHC class I peptide loading complex RNA binding acrosomal vesicle calcium ion binding carbohydrate binding cardiac muscle cell differentiation cell surface cellular response to electrical stimulus cellular response to lithium ion cellular response to virus cellular senescence collagen-containing extracellular matrix complement component C1q complex binding cortical actin cytoskeleton organization cortical granule cytolytic granule cytoplasm cytosol endocytic vesicle lumen endoplasmic reticulum lumen endoplasmic reticulum membrane endoplasmic reticulum quality control compartment endoplasmic reticulum-Golgi intermediate compartment membrane endoplasmic reticulum external side of plasma membrane extracellular exosome extracellular region extracellular space focal adhesion glucocorticoid receptor signaling pathway hormone binding integrin binding intracellular calcium ion homeostasis iron ion binding lumenal side of endoplasmic reticulum membrane mRNA binding membrane molecular sequestering activity negative regulation of DNA-templated transcription negative regulation of intracellular steroid hormone receptor signaling pathway negative regulation of neuron differentiation negative regulation of retinoic acid receptor signaling pathway negative regulation of transcription by RNA polymerase II negative regulation of translation negative regulation of trophoblast cell migration nuclear androgen receptor binding nuclear envelope nuclear export signal receptor activity nucleus peptide antigen assembly with MHC class I protein complex peptide binding perinuclear region of cytoplasm phagocytic vesicle membrane positive regulation of cell cycle positive regulation of cell population proliferation positive regulation of dendritic cell chemotaxis positive regulation of endothelial cell migration positive regulation of gene expression positive regulation of non-canonical NF-kappaB signal transduction positive regulation of phagocytosis positive regulation of substrate adhesion-dependent cell spreading protein export from nucleus protein folding chaperone protein folding in endoplasmic reticulum protein folding protein localization to nucleus protein maturation by protein folding protein stabilization protein-folding chaperone binding regulation of DNA-templated transcription regulation of apoptotic process regulation of meiotic nuclear division response to estradiol response to glycoside response to testosterone response to xenobiotic stimulus ribosome sarcoplasmic reticulum lumen sequestering of calcium ion smooth endoplasmic reticulum spermatogenesis ubiquitin protein ligase binding unfolded protein binding zinc ion binding	GO:0000122 GO:0001669 GO:0001849 GO:0002502 GO:0003677 GO:0003723 GO:0003729 GO:0005049 GO:0005178 GO:0005506 GO:0005509 GO:0005576 GO:0005615 GO:0005634 GO:0005635 GO:0005737 GO:0005783 GO:0005788 GO:0005789 GO:0005790 GO:0005829 GO:0005840 GO:0005925 GO:0006355 GO:0006457 GO:0006611 GO:0006874 GO:0007283 GO:0008270 GO:0008284 GO:0009410 GO:0009897 GO:0009986 GO:0010595 GO:0010628 GO:0016020 GO:0017148 GO:0022417 GO:0030246 GO:0030670 GO:0030866 GO:0031625 GO:0032355 GO:0033018 GO:0033116 GO:0033144 GO:0033574 GO:0034504 GO:0034975 GO:0036503 GO:0040020 GO:0042277 GO:0042562 GO:0042824 GO:0042921 GO:0042981 GO:0044183 GO:0044194 GO:0044322 GO:0045665 GO:0045787 GO:0045892 GO:0048387 GO:0048471 GO:0050681 GO:0050766 GO:0050821 GO:0051082 GO:0051087 GO:0051208 GO:0055007 GO:0060473 GO:0062023 GO:0070062 GO:0071257 GO:0071285 GO:0071682 GO:0090398 GO:0098553 GO:0098586 GO:0140313 GO:1900026 GO:1901164 GO:1901224 GO:1903416 GO:2000510
GL_000189	C-type lectin domain family 4 member K	Q9UJ71	3C22 3KQG 3P5D 3P5E 3P5F 3P5G 3P5H 3P5I 3P7F 3P7G 3P7H 4AK8 4N32 4N33 4N34 4N35 4N36 4N37 4N38 5G6U 7WZ8 7YTQ			Homo sapiens (human)	9606	1842 5090	carbohydrate binding clathrin-coated endocytic vesicle membrane defense response to virus early endosome membrane endocytic vesicle external side of plasma membrane mannose binding plasma membrane signaling receptor activity	GO:0005537 GO:0005886 GO:0009897 GO:0030139 GO:0030246 GO:0030669 GO:0031901 GO:0038023 GO:0051607
GL_000514	Galectin-9 Aliases: Galectin-9	O00182	2EAK 2EAL 2YY1 2ZHK 2ZHL 2ZHM 2ZHN 3LSD 3LSE 3NV1 3NV2 3NV3 3NV4 3WLU 3WV6	LfDB0274		Homo sapiens (human)	9606	1935 2987	ERK1 and ERK2 cascade carbohydrate binding cellular response to type II interferon cellular response to virus chemotaxis collagen-containing extracellular matrix cytoplasm cytosol disaccharide binding enzyme binding extracellular space female pregnancy galactose binding galactoside binding inflammatory response maternal process involved in female pregnancy natural killer cell tolerance induction negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of activated T cell proliferation negative regulation of chemokine production negative regulation of gene expression negative regulation of mast cell degranulation negative regulation of natural killer cell mediated cytotoxicity negative regulation of tumor necrosis factor production negative regulation of type II interferon production nucleus p38MAPK cascade positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of ERK1 and ERK2 cascade positive regulation of NF-kappaB transcription factor activity positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell positive regulation of activated T cell autonomous cell death positive regulation of canonical NF-kappaB signal transduction positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway positive regulation of dendritic cell apoptotic process positive regulation of dendritic cell chemotaxis positive regulation of dendritic cell differentiation positive regulation of gene expression positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-13 production positive regulation of interleukin-4 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of monocyte chemotactic protein-1 production positive regulation of non-canonical NF-kappaB signal transduction positive regulation of transforming growth factor beta production positive regulation of tumor necrosis factor production positive regulation of type II interferon production positive regulation of viral entry into host cell response to interleukin-1 response to lipopolysaccharide	GO:0002519 GO:0005534 GO:0005615 GO:0005634 GO:0005737 GO:0005829 GO:0006935 GO:0006954 GO:0007565 GO:0010628 GO:0010629 GO:0016936 GO:0019899 GO:0030246 GO:0032496 GO:0032682 GO:0032689 GO:0032720 GO:0032729 GO:0032731 GO:0032733 GO:0032735 GO:0032736 GO:0032753 GO:0032755 GO:0032757 GO:0032760 GO:0032834 GO:0038066 GO:0043123 GO:0043305 GO:0045953 GO:0046007 GO:0046598 GO:0048030 GO:0051092 GO:0060135 GO:0062023 GO:0070241 GO:0070371 GO:0070374 GO:0070555 GO:0071346 GO:0071636 GO:0071639 GO:0098586 GO:1901224 GO:2000510 GO:2000562 GO:2000563 GO:2000670 GO:2001190 GO:2001200 GO:2001269
GL_004115	Glucosamine 6-phosphate N-acetyltransferase	Q96EK6	2HUZ 2O28 3CXP 3CXQ 3CXS			Homo sapiens (human)	9606		Golgi membrane UDP-N-acetylglucosamine biosynthetic process cytosol endoplasmic reticulum-Golgi intermediate compartment endoplasmic reticulum endosome membrane glucosamine 6-phosphate N-acetyltransferase activity identical protein binding monosaccharide binding	GO:0000139 GO:0004343 GO:0005783 GO:0005793 GO:0005829 GO:0006048 GO:0010008 GO:0042802 GO:0048029
GL_005165	Peptidyl-glycine alpha-amidating monooxygenase	P19021				Homo sapiens (human)	9606		L-ascorbic acid binding calcium ion binding copper ion binding extracellular exosome extracellular region fatty acid primary amide biosynthetic process membrane peptide amidation peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity response to zinc ion secretory granule membrane transport vesicle membrane zinc ion binding	GO:0001519 GO:0004504 GO:0004598 GO:0005507 GO:0005509 GO:0005576 GO:0008270 GO:0010043 GO:0016020 GO:0030658 GO:0030667 GO:0031418 GO:0062112 GO:0070062
GL_000082	B-cell receptor CD22	P20273	5VKJ 5VKM 5VL3 7O52			Homo sapiens (human)	9606		B cell activation CD4 receptor binding IgM binding carbohydrate binding cell adhesion cell surface cytoplasm early endosome external side of plasma membrane extracellular exosome membrane negative regulation of B cell receptor signaling pathway negative regulation of calcium-mediated signaling negative regulation of immunoglobulin production neuronal cell body membrane plasma membrane protein phosphatase binding recycling endosome regulation of B cell proliferation regulation of endocytosis regulation of immune response sialic acid binding signaling receptor binding	GO:0001791 GO:0002638 GO:0005102 GO:0005737 GO:0005769 GO:0005886 GO:0007155 GO:0009897 GO:0009986 GO:0016020 GO:0019903 GO:0030100 GO:0030246 GO:0030888 GO:0032809 GO:0033691 GO:0042113 GO:0042609 GO:0050776 GO:0050849 GO:0050859 GO:0055037 GO:0070062
GL_000176	C-type lectin domain family 4 member C	Q8WTT0	3WBP 3WBQ 3WBR 4ZES 4ZET			Homo sapiens (human)	9606		adaptive immune response antifungal innate immune response carbohydrate binding external side of plasma membrane ficolin-1-rich granule membrane metal ion binding plasma membrane secretory granule membrane tertiary granule membrane	GO:0002250 GO:0005886 GO:0009897 GO:0030246 GO:0030667 GO:0046872 GO:0061760 GO:0070821 GO:0101003
GL_000639	L-selectin	P14151	2LGF 3CFW 5VC1			Homo sapiens (human)	9606		calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules carbohydrate binding cell adhesion external side of plasma membrane extracellular space glycosphingolipid binding heparin binding heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte cell-cell adhesion leukocyte tethering or rolling oligosaccharide binding plasma membrane protease binding response to cytokine secretory granule membrane sialic acid binding	GO:0002020 GO:0005509 GO:0005615 GO:0005886 GO:0007155 GO:0007157 GO:0007159 GO:0008201 GO:0009897 GO:0016339 GO:0030246 GO:0030667 GO:0033691 GO:0034097 GO:0043208 GO:0050901 GO:0070492
GL_000900	Polypeptide N-acetylgalactosaminyltransferase 14	Q96FL9				Homo sapiens (human)	9606		Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0016266 GO:0030246 GO:0046872
GL_002600	Hexokinase-2	P52789	2NZT 5HEX 5HFU 5HG1			Homo sapiens (human)	9606		ATP binding apoptotic mitochondrial changes canonical glycolysis carbohydrate phosphorylation cellular response to leukemia inhibitory factor centrosome cytosol establishment of protein localization to mitochondrion fructokinase activity fructose 6-phosphate metabolic process glucokinase activity glucose 6-phosphate metabolic process glucose binding glucose metabolic process glycolytic process hexokinase activity intracellular glucose homeostasis intracellular membrane-bounded organelle lactation maintenance of protein location in mitochondrion membrane mitochondrial outer membrane mitochondrion negative regulation of mitochondrial membrane permeability negative regulation of reactive oxygen species metabolic process positive regulation of angiogenesis positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization regulation of glucose import response to hypoxia response to ischemia sarcoplasmic reticulum	GO:0001666 GO:0001678 GO:0002931 GO:0004340 GO:0004396 GO:0005524 GO:0005536 GO:0005739 GO:0005741 GO:0005813 GO:0005829 GO:0006002 GO:0006006 GO:0006096 GO:0007595 GO:0008637 GO:0008865 GO:0016020 GO:0016529 GO:0035795 GO:0043231 GO:0045766 GO:0046324 GO:0046835 GO:0051156 GO:0061621 GO:0072655 GO:0072656 GO:1904925 GO:1990830 GO:2000378
GL_001840	Sucrase-isomaltase, intestinal	P14410	3LPO 3LPP			Homo sapiens (human)	9606		Golgi apparatus alpha-1,4-glucosidase activity apical plasma membrane brush border carbohydrate binding extracellular exosome oligo-1,6-glucosidase activity plasma membrane polysaccharide digestion sucrose alpha-glucosidase activity sucrose catabolic process	GO:0004558 GO:0004574 GO:0004575 GO:0005794 GO:0005886 GO:0005903 GO:0005987 GO:0016324 GO:0030246 GO:0044245 GO:0070062
GL_001666	Interleukin-2	P60568	1IRL 1M47 1M48 1M49 1M4A 1M4B 1M4C 1NBP 1PW6 1PY2 1QVN 1Z92 2B5I 2ERJ 3INK 3QAZ 3QB1 4NEJ 4NEM 5LQB 5M5E 5UTZ 6LX3 6LXW 6VWU 6YE3 7DR4 7M2G 7RA9 7RAA 7YZJ 7ZMZ			Homo sapiens (human)	9606		T cell differentiation activated T cell proliferation adaptive immune response carbohydrate binding cell adhesion cell-cell signaling cytokine activity extracellular region extracellular space extrinsic apoptotic signaling pathway in absence of ligand glycosphingolipid binding growth factor activity immune response interleukin-2 receptor binding interleukin-2-mediated signaling pathway kappa-type opioid receptor binding kinase activator activity leukocyte activation involved in immune response natural killer cell activation negative regulation of B cell apoptotic process negative regulation of T-helper 17 cell differentiation negative regulation of apoptotic process negative regulation of inflammatory response negative regulation of lymphocyte proliferation negative regulation of protein phosphorylation positive regulation of B cell proliferation positive regulation of activated T cell proliferation positive regulation of cell growth positive regulation of cell population proliferation positive regulation of cytosolic calcium ion concentration positive regulation of dendritic spine development positive regulation of immunoglobulin production positive regulation of inflammatory response positive regulation of interleukin-17 production positive regulation of isotype switching to IgG isotypes positive regulation of plasma cell differentiation positive regulation of regulatory T cell differentiation positive regulation of tissue remodeling positive regulation of transcription by RNA polymerase II positive regulation of type II interferon production positive regulation of tyrosine phosphorylation of STAT protein protein kinase C-activating G protein-coupled receptor signaling pathway regulation of CD4-positive, alpha-beta T cell proliferation regulation of T cell homeostatic proliferation response to ethanol response to tacrolimus transcription by RNA polymerase II	GO:0001933 GO:0002250 GO:0002366 GO:0002639 GO:0002903 GO:0005125 GO:0005134 GO:0005576 GO:0005615 GO:0006366 GO:0006955 GO:0007155 GO:0007204 GO:0007205 GO:0007267 GO:0008083 GO:0008284 GO:0019209 GO:0030101 GO:0030217 GO:0030246 GO:0030307 GO:0030890 GO:0031851 GO:0032729 GO:0032740 GO:0034105 GO:0038110 GO:0042104 GO:0042531 GO:0043066 GO:0043208 GO:0045471 GO:0045591 GO:0045944 GO:0046013 GO:0048304 GO:0050672 GO:0050728 GO:0050729 GO:0050798 GO:0060999 GO:0097192 GO:1900100 GO:1901327 GO:2000320 GO:2000561
GL_001020	Pulmonary surfactant-associated protein A1	Q8IWL2				Homo sapiens (human)	9606		carbohydrate binding clathrin-coated endocytic vesicle collagen trimer endoplasmic reticulum membrane extracellular region extracellular space lamellar body lipid transporter activity multivesicular body opsonization respiratory gaseous exchange by respiratory system	GO:0005319 GO:0005576 GO:0005581 GO:0005615 GO:0005771 GO:0005789 GO:0007585 GO:0008228 GO:0030246 GO:0042599 GO:0045334
GL_002047	P-selectin	P16109	1FSB 1G1Q 1G1R 1G1S 1HES			Homo sapiens (human)	9606		calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-dependent protein binding calcium-mediated signaling using intracellular calcium source cell adhesion cell-cell adhesion defense response to Gram-negative bacterium external side of plasma membrane extracellular space fucose binding glycosphingolipid binding heparin binding heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules inflammatory response integrin binding leukocyte cell-cell adhesion leukocyte tethering or rolling lipopolysaccharide binding oligosaccharide binding plasma membrane platelet alpha granule membrane platelet dense granule membrane positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of platelet activation regulation of integrin activation response to cytokine response to lipopolysaccharide sialic acid binding	GO:0001530 GO:0002687 GO:0005178 GO:0005509 GO:0005615 GO:0005886 GO:0006954 GO:0007155 GO:0007157 GO:0007159 GO:0008201 GO:0009897 GO:0010572 GO:0016339 GO:0031088 GO:0031092 GO:0032496 GO:0033623 GO:0033691 GO:0034097 GO:0035584 GO:0042806 GO:0043208 GO:0048306 GO:0050829 GO:0050901 GO:0051897 GO:0070492 GO:0098609 GO:1903238
GL_000835	Oxidized low-density lipoprotein receptor 1	P78380	1YPO 1YPQ 1YPU 1YXJ 1YXK 3VLG 6TL7 6TL9 6TLA 7R8U 7W5D 7XMP			Homo sapiens (human)	9606		blood circulation carbohydrate binding extracellular region identical protein binding immune system process inflammatory response intracellular membrane-bounded organelle leukocyte cell-cell adhesion lipoprotein metabolic process low-density lipoprotein particle receptor activity membrane raft membrane nucleoplasm plasma membrane proteolysis receptor complex specific granule membrane tertiary granule membrane	GO:0002376 GO:0005041 GO:0005576 GO:0005654 GO:0005886 GO:0006508 GO:0006954 GO:0007159 GO:0008015 GO:0016020 GO:0030246 GO:0035579 GO:0042157 GO:0042802 GO:0043231 GO:0043235 GO:0045121 GO:0070821
GL_002343	Cation-independent mannose-6-phosphate receptor	P11717	1E6F 1GP0 1GP3 1GQB 1JPL 1JWG 1LF8 2CNJ 2L29 2L2A 2M68 2M6T 2V5N 2V5O 2V5P 5IEI 6N5X 6N5Y 6P8I 6V02 6Z30 6Z31 6Z32 8AFZ			Homo sapiens (human)	9606		G protein-coupled receptor signaling pathway G-protein alpha-subunit binding Golgi apparatus Golgi membrane animal organ regeneration cell surface clathrin coat clathrin-coated endocytic vesicle membrane early endosome endocytic vesicle endosome membrane endosome enzyme binding extracellular exosome focal adhesion identical protein binding insulin-like growth factor II binding insulin-like growth factor binding insulin-like growth factor receptor activity late endosome liver development lysosomal transport mannose binding membrane nuclear envelope lumen perinuclear region of cytoplasm phosphoprotein binding plasma membrane positive regulation by host of viral process positive regulation of apoptotic process post-embryonic development receptor-mediated endocytosis response to retinoic acid response to tetrachloromethane retinoic acid binding retromer complex binding secretory granule membrane signal transduction signaling receptor activity spermatogenesis trans-Golgi network membrane trans-Golgi network transport vesicle trans-Golgi network transport vesicle	GO:0000139 GO:0001889 GO:0001965 GO:0001972 GO:0005010 GO:0005520 GO:0005537 GO:0005641 GO:0005768 GO:0005769 GO:0005770 GO:0005794 GO:0005802 GO:0005886 GO:0005925 GO:0006898 GO:0007041 GO:0007165 GO:0007186 GO:0007283 GO:0009791 GO:0009986 GO:0010008 GO:0016020 GO:0019899 GO:0030118 GO:0030133 GO:0030139 GO:0030140 GO:0030667 GO:0030669 GO:0031100 GO:0031995 GO:0032526 GO:0032588 GO:0038023 GO:0042802 GO:0043065 GO:0044794 GO:0048471 GO:0051219 GO:0070062 GO:1904772 GO:1905394
GL_000877	Polycystin-1-like protein 2	Q7Z442				Homo sapiens (human)	9606		calcium channel activity calcium ion binding carbohydrate binding detection of mechanical stimulus membrane	GO:0005262 GO:0005509 GO:0016020 GO:0030246 GO:0050982
GL_000534	Grifin	A4D1Z8				Homo sapiens (human)	9606		carbohydrate binding	GO:0030246

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