p130Cas linkage to MAPK signaling for integrins
|
|
|
- APBB1IP
- BCAR1
- CRK
- F8VWF
- FN1
- ITGA2B
- ITGB3
- PTK2
- RAP1A
- RAP1B
- SRC
- TLN1
- VWF
|
|
MET activates RAP1 and RAC1
|
|
|
- CRK
- CRKL
- DOCK7
- GAB1
- GRB2
- HGF
- MET
- RAC1
- RAP1A
- RAP1B
- RAPGEF1
|
|
Transcriptional and post-translational regulation of MITF-M expression and activity
|
|
|
- AIMP1
- AIMP2
- AKT3
- CREBBP
- DARS1
- EEF1E1
- EPRS1
- GSK3B
- IARS1
- KARS1
- KIT
- KITLG
- LARS1
- LOC100684571
- MAPK1
- MAPK3
- MARS1
- MGF
- MITF
- QARS1
- RARS1
- RPS6KA1
- SIRT1
- SOX10
- TBX3
- WNT3A
- XPO1
|
|
Adenosine P1 receptors
|
|
|
- ADORA1
- ADORA2A
- ADORA3
- RDC7
- RDC8
|
|
Class B/2 (Secretin family receptors)
|
|
|
- ADGRE1
- ADGRE3
- ADGRE5
- CD55
- CRH
- CRHBP
- CRHR1
- CRHR2
- LOC484897
- PTH
- PTH1
- PTH1R
- PTH2
- PTH2R
- PTHLH
- PTHR1
- UCN
- UCN3
|
|
Peptide ligand-binding receptors
|
|
|
- ACKR1
- AGT
- AGTR1
- AGTR2
- BDKRB1
- BDKRB2
- BRS3
- Bdkrb2
- C3
- C3AR1
- C5
- C5AR1
- C5AR2
- CCK
- CCKBR
- CXCL8
- ECE1
- ECE2
- EDN1
- EDN2
- EDN3
- EDNRA
- EDNRB
- F2
- F2R
- F2RL1
- F2RL2
- F2RL3
- GAL
- GALR1
- GALR2
- GALR3
- GPER1
- GPR37
- GPR37L1
- GRP
- GRPR
- IL8
- KEL
- KISS1R
- KNG1
- Kiss1
- MC2R
- MC3R
- MC4R
- MC5R
- MCH
- MCHR1
- MCHR2
- MLN
- MLNR
- MTLR
- NLN
- NMB
- NMBR
- NMS
- NMU
- NMUR1
- NMUR2
- NPB
- NPBWR1
- NPS
- NPSR1
- NPY
- NPY1R
- NPY2R
- NPY4R
- NPY5
- NPY5R
- NTS
- NTSR1
- NTSR2
- OPRD1
- OPRK1
- OPRM1
- PDYN
- PENK
- PMCH
- POMC
- PPY
- PRLH
- PRLHR
- PROK1
- PROK2
- PROKR1
- PSAP
- PYY
- SST
- SSTR1
- SSTR2
- SSTR3
- SSTR5
- TRH
- TRHR
- UTS2B
- UTS2R
- XK
|
|
Adherens junctions interactions
|
|
|
- AFDN
- CADM1
- CADM2
- CADM3
- CDH1
- CDH10
- CDH11
- CDH12
- CDH13
- CDH15
- CDH17
- CDH18
- CDH2
- CDH24
- CDH3
- CDH4
- CDH5
- CDH6
- CDH7
- CDH8
- CDH9
- CTNNA1
- CTNNB1
- CTNND1
- JUP
- NECTIN1
- NECTIN2
- NECTIN3
- NECTIN4
|
|
ECM proteoglycans
|
|
|
- ACAN
- AGRN
- BCAN
- BGN
- COL9A1
- COL9A2
- COL9A3
- COMP
- DCN
- DCN1C
- DMP1
- DSPP
- HAPLN1
- ITGA2
- ITGA2B
- ITGA7
- ITGA8
- ITGA9
- ITGAD
- ITGAV
- ITGB1
- ITGB3
- ITGB5
- ITGB6
- MATN1
- MATN3
- MATN4
- NCAN
- SEBOX
- SERPINE1
- SPARC
- TNC
- TNR
- VCAN
|
|
Keratan sulfate degradation
|
|
|
- ACAN
- FMOD
- GLB1
- GLB1L
- GLB1L2
- GNS
- HEXA
- HEXB
- KERA
- LUM
- OGN
- OMD
- PRELP
|
|
HS-GAG degradation
|
|
|
- AGRN
- GLB1
- GLB1L
- GLB1L2
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- GUSB
- HPSE
- HPSE2
- IDS
- IDUA
- NAGLU
- SDC1
- SDC3
- SDC4
- SGSH
- ids
|
|
A tetrasaccharide linker sequence is required for GAG synthesis
|
|
|
- AGRN
- B3GALT6
- B3GAT1
- B3GAT2
- B3GAT3
- B4GALT7
- BCAN
- BGN
- CSPG4
- CSPG5
- DCN
- DCN1C
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- NCAN
- SDC1
- SDC3
- SDC4
- VCAN
- XYLT1
- XYLT2
|
|
Regulation of Glucokinase by Glucokinase Regulatory Protein
|
|
|
- AAAS
- GCK
- GCKR
- NDC1
- NUP107
- NUP133
- NUP153
- NUP155
- NUP160
- NUP188
- NUP205
- NUP210
- NUP214
- NUP35
- NUP37
- NUP42
- NUP43
- NUP50
- NUP54
- NUP58
- NUP62
- NUP85
- NUP88
- NUP93
- NUP98
- POM121C
- RANBP2
- SEC13
- TPR
|
|
Regulation of IGF Activity by IGFBP
|
|
|
- ADAM10
- AFP
- AHSG
- ALB
- AMBN
- AMELX
- AMTN
- ANO8
- APLP2
- APOA1
- APOA2
- APOA5
- APOB
- APOE
- APP
- BMP15
- BMP4
- BPIFB2
- C3
- CALU
- CCN1
- CDH2
- CHGB
- CHRDL1
- CKAP4
- COA5
- CP
- CSF1
- DMP1
- DNAJC3
- ENAM
- F5
- FAM20A
- FAM20C
- FBN1
- FGA
- FGF23
- FGF8B
- FN1
- FSTL1
- FSTL3
- FUCA2
- GAS6
- GOLM1
- GPC3
- GRP94
- HRC
- HSP90B1
- HSPC4
- IGF1
- IGF2
- IGFBP2
- IGFBP3
- IGFBP4
- IGFBP5
- IGFBP6
- IGFBP7
- IGFIA
- IL6
- ITIH2
- KNG1
- KTN1
- LGALS1
- LOC102156332
- LOC481722
- LOC607874
- LTBP1
- MATN3
- MBTPS1
- MEGF6
- MELTF
- MEN1
- MEPE
- MFGE8
- MIA3
- MXRA8
- NOTUM
- NUCB1
- P4HB
- PAPPA
- PAPPA2
- PDIA6
- PENK
- PNPLA2
- PRKCSH
- PROC
- PRSS23
- QSOX1
- RCN1
- SCG2
- SCG3
- SERPINA1
- SERPINC1
- SERPIND1
- SPARCL1
- SPP1
- SPP2
- STC2
- TGOLN2
- TIMP1
- TMEM132A
- TNC
- TRA1
- VCAN
- VGF
- VWA1
- WFS1
|
|
Post-translational protein phosphorylation
|
|
|
- ADAM10
- AFP
- AHSG
- ALB
- AMBN
- AMELX
- AMTN
- ANO8
- APLP2
- APOA1
- APOA2
- APOA5
- APOB
- APOE
- APP
- BMP15
- BMP4
- BPIFB2
- C3
- CALU
- CCN1
- CDH2
- CHGB
- CHRDL1
- CKAP4
- COA5
- CP
- CSF1
- DMP1
- DNAJC3
- ENAM
- F5
- FAM20A
- FAM20C
- FBN1
- FGA
- FGF23
- FGF8B
- FN1
- FSTL1
- FSTL3
- FUCA2
- GAS6
- GOLM1
- GPC3
- GRP94
- HRC
- HSP90B1
- HSPC4
- IGFBP3
- IGFBP4
- IGFBP5
- IGFBP7
- IL6
- ITIH2
- KNG1
- KTN1
- LGALS1
- LOC102156332
- LOC481722
- LOC607874
- LTBP1
- MATN3
- MBTPS1
- MEGF6
- MELTF
- MEN1
- MEPE
- MFGE8
- MIA3
- MXRA8
- NOTUM
- NUCB1
- P4HB
- PDIA6
- PENK
- PNPLA2
- PRKCSH
- PROC
- PRSS23
- QSOX1
- RCN1
- SCG2
- SCG3
- SERPINA1
- SERPINC1
- SERPIND1
- SPARCL1
- SPP1
- SPP2
- STC2
- TGOLN2
- TIMP1
- TMEM132A
- TNC
- TRA1
- VCAN
- VGF
- VWA1
- WFS1
|
|
Cytoprotection by HMOX1
|
- Albumin
- Biliverdin reductase A
- Cytochrome c oxidase polypeptide VIa
- Cytochrome c oxidase polypeptide VIa
- Cytochrome c oxidase subunit 4
- Cytochrome c oxidase subunit 4
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome c oxidase subunit 5B, mitochondrial
- Cytochrome c oxidase subunit 6A2, mitochondrial
- Cytochrome c oxidase subunit 6B2
- Cytochrome c oxidase subunit 6C
- Cytochrome c oxidase subunit 7A1, mitochondrial
- Cytochrome c oxidase subunit 7A2 like
- Cytochrome c oxidase subunit 7A2, mitochondrial
- Cytochrome c oxidase subunit 7B, mitochondrial
- Cytochrome c oxidase subunit 7B, mitochondrial
- Cytochrome c oxidase subunit 7C, mitochondrial
- Cytochrome c oxidase subunit 8
- Cytochrome c oxidase subunit NDUFA4
- Cytochrome c oxidase subunit
- Cytochrome c oxidase subunit
- Cytochrome c oxidase subunit
- Cytochrome c
- DNA helicase
- F-box-like/WD repeat-containing protein TBL1X
- Fatty acid-binding protein, liver
- Globin A2
- Globin domain-containing protein
- HIG1 hypoxia inducible domain family member 1C
- Heme oxygenase 1
- Histone deacetylase 3
- Histone-arginine methyltransferase CARM1
- Mediator of RNA polymerase II transcription subunit 1
- Multidrug resistance-associated protein 1
- Multidrug resistance-associated protein 1
- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4
- NDUFA4 mitochondrial complex associated
- NDUFA4 mitochondrial complex associated
- Nuclear receptor coactivator 6
- Nuclear receptor coactivator
- Nuclear receptor coactivator
- Nuclear receptor corepressor 1
- Nuclear receptor corepressor 2
- Peroxisome proliferator-activated receptor alpha
- Retinoic acid receptor RXR
- SIN3 transcription regulator family member A
- SIN3 transcription regulator family member B
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
- TBL1X/Y related 1
- Trimethylguanosine synthase
- heme oxygenase (biliverdin-producing)
- histone acetyltransferase
|
|
- ABCC1
- ALB
- BLVRA
- CARM1
- CHD9
- COX4I1
- COX4I2
- COX5A
- COX5B
- COX6A2
- COX6B2
- COX7A1
- COX7A2L
- CREBBP
- CYC
- CYCS
- FABP1
- GLNA2
- GLNA3
- HBQ1
- HDAC3
- HIGD1C
- HMOX1
- HMOX2
- LOC100682956
- LOC100684983
- LOC100688724
- LOC119863903
- LOC119868178
- LOC477508
- LOC606860
- LOC609402
- LOC612644
- MED1
- MRP1
- NCOA1
- NCOA2
- NCOA6
- NCOR1
- NCOR2
- PPARA
- RXRA
- SIN3A
- SIN3B
- SMARCD3
- TBL1X
- TBL1XR1
- TGS1
|
|
Phase I - Functionalization of compounds
|
|
|
- AADAC
- AHR
- AHRR
- ALDH3
- ALDH3A1
- AOC2
- AOC3
- ARNT
- ARNT2
- BPHL
- C5BR
- CBR3
- CES2
- CES5A
- CMBL
- CYB5B
- CYB5R3
- CYP2B6
- CYP3A12
- DIA1
- EPHX1
- LOC119868939
- LOC119875773
- LOC119876349
- MTARC1
- NQO2
|
|
Fructose biosynthesis
|
|
|
|
|
COPII-mediated vesicle transport
|
- Alpha 1 antitrypsin
- Ankyrin repeat domain 28
- Bet1 golgi vesicular membrane trafficking protein
- Casein kinase I isoform delta
- Coagulation factor V
- Cornichon family AMPA receptor auxiliary protein 1
- Cornichon family AMPA receptor auxiliary protein 3
- Dipeptidyl peptidase 1
- EF-hand domain-containing protein
- EGF-like domain-containing protein
- Folate receptor alpha
- Gamma-soluble NSF attachment protein
- General vesicular transport factor p115
- Glutamate receptor
- Golgi SNAP receptor complex member 2
- Lectin, mannose binding 1 like
- Lectin, mannose binding 1
- Lectin, mannose binding 2 like
- MAC-inhibitory protein
- NSF attachment protein alpha
- NSF attachment protein beta
- Prolactin regulatory element-binding protein
- Protein SEC13 homolog
- Protein cornichon homolog 2
- Protein phosphatase 6 regulatory subunit 1
- Protein phosphatase 6 regulatory subunit 3
- Protein transport protein SEC23
- Protein transport protein Sec31A
- Protein transport protein sec16
- Protein transport protein sec16
- Ras-related protein Rab-1A
- SEC22 homolog A, vesicle trafficking protein
- SEC22 homolog B, vesicle trafficking protein
- SEC22 homolog C, vesicle trafficking protein
- SEC23 interacting protein
- SEC24 homolog A, COPII coat complex component
- SEC24 homolog B, COPII coat complex component
- SEC24 homolog C, COPII coat complex component
- SEC24 homolog D, COPII coat complex component
- SEC31 homolog B, COPII coat complex component
- Sec1 family domain containing 1
- Serine/threonine-protein phosphatase
- Small COPII coat GTPase SAR1B
- Syntaxin 17
- Syntaxin 5
- TBC1 domain family member 20
- Trafficking from ER to golgi regulator
- Trafficking protein particle complex subunit 10
- Trafficking protein particle complex subunit 2-like protein
- Trafficking protein particle complex subunit 2
- Trafficking protein particle complex subunit 6A
- Trafficking protein particle complex subunit 6B
- Trafficking protein particle complex subunit 9
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit
- Transmembrane emp24 domain-containing protein 10
- Transmembrane p24 trafficking protein 2
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Vesicle-fusing ATPase
- Vesicular integral-membrane protein VIP36
- YKT6 v-SNARE homolog
- cathepsin X
- small monomeric GTPase
|
|
- ANKRD28
- AREG
- BET1
- CD59
- CNIH1
- CNIH2
- CNIH3
- CSNK1D
- CTSC
- CTSZ
- F5
- GOLGA2
- GORASP1
- GOSR2
- GRIA1
- LMAN1
- LMAN1L
- LMAN2
- LMAN2L
- LOC119876190
- LOC609612
- MCFD2
- NAPA
- NAPB
- NAPG
- NSF
- PPP6C
- PPP6R1
- PPP6R3
- PREB
- RAB1
- RAB1A
- SCFD1
- SEC13
- SEC16A
- SEC16B
- SEC22A
- SEC22C
- SEC23A
- SEC23IP
- SEC24A
- SEC24B
- SEC24C
- SEC24D
- SEC31A
- SEC31B
- SERPINA1
- STX17
- STX5
- TBC1D20
- TFG
- TGFA
- TMED10
- TMED2
- TRAPPC1
- TRAPPC10
- TRAPPC2
- TRAPPC2L
- TRAPPC3
- TRAPPC4
- TRAPPC6A
- TRAPPC6B
- TRAPPC9
- USO1
- YKT6
|
|
Cargo concentration in the ER
|
|
|
- AREG
- CD59
- CNIH1
- CNIH2
- CNIH3
- CTSC
- CTSZ
- F5
- GOSR2
- GRIA1
- LMAN1
- LMAN1L
- LMAN2
- LMAN2L
- LOC119876190
- LOC609612
- MCFD2
- MIA2
- PREB
- SEC23A
- SEC24A
- SEC24B
- SEC24C
- SEC24D
- SERPINA1
- STX5
- TGFA
- TMED10
- TMED2
|
|
Reactions specific to the complex N-glycan synthesis pathway
|
|
|
- CHST10
- FUCA1
- FUT5
- FUT8
- MAN2A1
- MAN2A2
- MGAT2
|
|
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
|
|
|
- ALG1
- ALG12
- ALG14
- ALG2
- ALG3
- ALG6
- ALG8
- ALG9
- DPAGT1
- MPDU1
|
|
N-Glycan antennae elongation
|
- Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
- Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase
- Beta-1,4-galactosyltransferase
- MGAT4 family member C
- ST3 beta-galactoside alpha-2,3-sialyltransferase 4
- ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
- ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
- ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
- alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase
- beta-galactoside alpha-(2,6)-sialyltransferase
|
|
- B4GALT1
- B4GALT2
- B4GALT3
- B4GALT4
- B4GALT5
- B4GALT6
- COA5
- MGAT4B
- MGAT4C
- MGAT5
- ST3GAL4
- ST6GAL1
- ST8SIA2
- ST8SIA3
- ST8SIA6
|
|
Glycogen breakdown (glycogenolysis)
|
|
|
- AGL
- CALM2
- GAA
- GYG1
- GYG2
- PHKA1
- PHKA2
- PHKB
- PHKG2
- PYGL
- PYGM
|
|
CS/DS degradation
|
|
|
- ARSB
- BCAN
- BGN
- CSPG4
- CSPG5
- DCN
- DCN1C
- HEXA
- HEXB
- HYAL1
- IDS
- IDUA
- NCAN
- VCAN
- arsb
- ids
|
|
Sialic acid metabolism
|
- Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
- Beta-galactosidase
- Beta-galactoside alpha-2,6-sialyltransferase 2
- CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
- CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase
- Carboxypeptidase
- Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
- Lactosylceramide alpha-2,3-sialyltransferase
- N-acetylneuraminate lyase
- N-acetylneuraminate synthase
- N-acylneuraminate cytidylyltransferase
- ST3 beta-galactoside alpha-2,3-sialyltransferase 3
- ST3 beta-galactoside alpha-2,3-sialyltransferase 4
- ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
- ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
- ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
- ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
- ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
- ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
- ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
- ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
- Sialidase-1
- Solute carrier family 17 member 5
- Solute carrier family 35 member A1
- Type 2 lactosamine alpha-2,3-sialyltransferase
- Uncharacterized protein
- alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase
- alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase
- beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase
- beta-galactoside alpha-(2,6)-sialyltransferase
- exo-alpha-sialidase
- exo-alpha-sialidase
- exo-alpha-sialidase
|
|
- CMAS
- CTSA
- GLB1
- GNE
- NANP
- NANS
- NEU1
- NEU2
- NEU3
- NEU4
- NPL
- SLC17A5
- SLC35A1
- ST3GAL1
- ST3GAL2
- ST3GAL3
- ST3GAL4
- ST3GAL5
- ST3GAL6
- ST6GAL1
- ST6GAL2
- ST6GALNAC1
- ST6GALNAC2
- ST6GALNAC3
- ST6GALNAC4
- ST6GALNAC5
- ST6GALNAC6
- ST8SIA1
- ST8SIA2
- ST8SIA3
- ST8SIA4
- ST8SIA5
- ST8SIA6
|
|