GlyCosmos Portal

Canis familiaris (dog)

Summary

Taxonomy ID: 9615
PubChem Taxonomy: 9615

Genes (1435) Glycans (57) Glycoproteins (513) Lectins (17) Pathways (270)

Displaying entries **201 - 225** of **270** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	GlyTouCan ID
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	Acyl-coenzyme A oxidase Bile acid-CoA Bile salt export pump Cytochrome P450 family 27 subfamily A member 1 Cytochrome P450 family 7 subfamily A member 1 Cytochrome P450 family 7 subfamily B member 1 Cytochrome P450 family 8 subfamily B member 1 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 Hydroxysteroid 17-beta dehydrogenase 4 NADP-dependent oxidoreductase domain-containing protein Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor subfamily 1 group H member 4 Retinoic acid receptor RXR Sterol carrier protein 2 long-chain-fatty-acid--CoA ligase long-chain-fatty-acid--CoA ligase palmitoyl-CoA hydrolase	A0A8I3MAI7 A0A8I3N1E1 A0A8I3N2S7 A0A8I3N3X9 A0A8I3NIH7 A0A8I3NZF5 A0A8I3P4G5 A0A8I3P7P8 A0A8I3PDX5 A0A8I3PFY5 A0A8I3PRC4 A0A8I3PYI4 A0A8I3RWQ9 A0A8I3RZP4 A0A8I3S339 A0A8I3S6P6 A0A8I3SAZ3 B8K1W2	ACOT8 ACOX2 Abcb11e BAAT BSEP CYP27A1 CYP7A1 CYP7B1 CYP8B1 HSD17B4 HSD3B7 LOC119874618 NCOA1 NCOA2 NR1H4 RXRA SCP2 SLC27A2 SLC27A5
Recycling of bile acids and salts	ABC-type glutathione-S-conjugate transporter Albumin Bile acid-CoA Bile salt export pump Ileal sodium/bile acid cotransporter Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor subfamily 1 group H member 4 Retinoic acid receptor RXR Solute carrier family 10 member 1 Solute carrier family 51 subunit alpha Solute carrier family 51 subunit beta Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member StAR related lipid transfer domain containing 5 long-chain-fatty-acid--CoA ligase	A0A8I3MAI7 A0A8I3MLS9 A0A8I3MY68 A0A8I3N1E1 A0A8I3N2S7 A0A8I3NIH7 A0A8I3NUI6 A0A8I3NXT1 A0A8I3PI53 A0A8I3PRC4 A0A8I3PYI4 A0A8I3Q2C1 A0A8I3RTD6 A0A8I3S0X8 B8K1W2 Q70HQ9	ABCC3 ALB Abcb11e BAAT BSEP NCOA1 NCOA2 NR1H4 RXRA SLC10A1 SLC10A2 SLC27A5 SLC51A SLC51B SLCO1A2 SLCO1B2 SLCO1B3 STARD5 slc10a2
Amino acid transport across the plasma membrane	Amino acid transporter Amino acid transporter Large neutral amino acids transporter small subunit 2 Large neutral amino acids transporter small subunit 3 Large neutral amino acids transporter small subunit 4 PX domain-containing protein Sodium- and chloride-dependent betaine transporter Sodium-coupled neutral amino acid symporter 2 Solute carrier family 16 member 10 Solute carrier family 25 member 29 Solute carrier family 3 member 1 Solute carrier family 3 member 2 Solute carrier family 36 member 1 Solute carrier family 36 member 2 Solute carrier family 36 member 4 Solute carrier family 38 member 1 Solute carrier family 38 member 3 Solute carrier family 38 member 4 Solute carrier family 38 member 5 Solute carrier family 6 member 6 Solute carrier family 7 member 10 Solute carrier family 7 member 11 Solute carrier family 7 member 1 Solute carrier family 7 member 2 Solute carrier family 7 member 5 Solute carrier family 7 member 9 Transporter Transporter Transporter Transporter Transporter Y+L amino acid transporter 2	A0A8I3MAA4 A0A8I3MHT3 A0A8I3MLB5 A0A8I3MST0 A0A8I3MWJ8 A0A8I3MX32 A0A8I3MZX5 A0A8I3NCF6 A0A8I3NJI9 A0A8I3NLL1 A0A8I3NQ27 A0A8I3NVM1 A0A8I3P2L3 A0A8I3P2T9 A0A8I3PCG7 A0A8I3PEA9 A0A8I3PHP5 A0A8I3PKJ6 A0A8I3PS32 A0A8I3PSN6 A0A8I3Q1D1 A0A8I3Q549 A0A8I3QAI5 A0A8I3RRM5 A0A8I3RSS1 A0A8I3RYK4 A0A8I3S220 A0A8I3S3F6 A0A8I3S5V8 A0A8I3SAV9 E2QXB4 P27799	SLC16A10 SLC1A4 SLC1A5 SLC25A29 SLC36A1 SLC36A3 SLC36A4 SLC38A1 SLC38A2 SLC38A3 SLC38A4 SLC38A5 SLC3A1 SLC3A2 SLC43A1 SLC43A2 SLC6A12 SLC6A14 SLC6A15 SLC6A18 SLC6A19 SLC6A20 SLC6A6 SLC7A1 SLC7A10 SLC7A11 SLC7A2 SLC7A5 SLC7A6 SLC7A8 SLC7A9 SNX12
Neurotransmitter receptors and postsynaptic signal transmission	5-hydroxytryptamine receptor 3A 5-hydroxytryptamine receptor 3B 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3E Glycine receptor alpha 1 Glycine receptor alpha 2 Glycine receptor alpha 3 Glycine receptor beta	A0A8I3MA77 A0A8I3MAG0 A0A8I3MZA4 A0A8I3NSZ3 A0A8I3P3M8 A0A8I3PQC9 A0A8I3Q2Z5 A0A8I3Q6S9 A0A8I3S5H9	GLRA1 GLRA2 GLRA3 GLRB HTR3A HTR3B HTR3C HTR3E LOC478649
TNFR1-induced NF-kappa-B signaling pathway	Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 E3 ubiquitin-protein ligase XIAP IkappaB kinase Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator Optineurin RBR-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Small ribosomal subunit protein RACK1 Spermatogenesis associated 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TNF receptor-associated factor TNFR-Cys domain-containing protein Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Uncharacterized protein ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A8I3MA34 A0A8I3MDM0 A0A8I3MQC7 A0A8I3MSL4 A0A8I3MYA4 A0A8I3N1V1 A0A8I3N4F2 A0A8I3N7L6 A0A8I3NEJ2 A0A8I3NMB6 A0A8I3NP69 A0A8I3P2P4 A0A8I3P499 A0A8I3P4Z1 A0A8I3PLL0 A0A8I3PS24 A0A8I3PWL6 A0A8I3Q3L1 A0A8I3RSQ2 A0A8I3RUY7 A0A8I3RZA9 A0A8I3S2L7 A0A8I3S792 A0A8I3S794 A1E2V0 P51742 Q38IV1	BIRC2 BIRC3 BIRC4 CHUK CYLD IKBKB IKBKG IRF9 MAP3K7 OPTN OTUD1 OTUD7B RACK1 RBCK1 RIPK1 SPATA2 TAB1 TAB2 TAB3 TNF TNFA TNFAIP3 TNFRSF1A TNFSF2 TRADD TRAF2 USP2 USP21 USP4 XIAP
Regulation of TNFR1 signaling	Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 CAP-Gly domain containing linker protein 3 Caspase 8 Caspase 9 E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase XIAP IkappaB kinase Inhibitor of nuclear factor kappa B kinase subunit epsilon Inhibitor of nuclear factor kappa-B kinase subunit alpha MAP kinase-activating death domain protein NF-kappa-B essential modulator Optineurin RBR-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Serine/threonine-protein kinase Signal peptide peptidase like 2A Signal peptide peptidase like 2B Small ribosomal subunit protein RACK1 Spermatogenesis associated 2 TANK binding kinase 1 TNF receptor-associated factor TNFR-Cys domain-containing protein Tax1 binding protein 1 Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin B Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin conjugating enzyme E2 D3 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A8I3MA34 A0A8I3MAP5 A0A8I3MDM0 A0A8I3MJ82 A0A8I3MKR0 A0A8I3MLM6 A0A8I3MMN5 A0A8I3MQC7 A0A8I3MSL4 A0A8I3MYA4 A0A8I3N1V1 A0A8I3N4F2 A0A8I3NEJ2 A0A8I3NFB9 A0A8I3NK16 A0A8I3NLZ9 A0A8I3NP69 A0A8I3NS04 A0A8I3P2P4 A0A8I3P499 A0A8I3PLX1 A0A8I3PRU0 A0A8I3PS24 A0A8I3PT83 A0A8I3PW29 A0A8I3PWL6 A0A8I3PZS6 A0A8I3Q155 A0A8I3Q3L1 A0A8I3QYD0 A0A8I3RSQ2 A0A8I3RUY7 A0A8I3RZA9 A0A8I3RZI9 A0A8I3S2L7 A0A8I3S5W5 A0A8I3S792 A0A8I3S794 A1E2V0 P51742 P63050 Q38IV1 Q38JA9	BIRC2 BIRC3 BIRC4 CASP8 CASP9 CHUK CLIP3 CYLD IKBKB IKBKE IKBKG IRF9 MADD MIB2 OPTN OTUD1 OTUD7B RACK1 RBCK1 RIPK1 RPS27A SPATA2 SPPL2A SPPL2B STUB1 TAX1BP1 TBK1 TNF TNFA TNFAIP3 TNFRSF1A TNFSF2 TRADD TRAF2 UBA52 UBB UBC UBCEP2 UBE2D1 UBE2D2 UBE2D3 UBE2L3 ULK1 USP2 USP21 USP4 XIAP
Ion transport by P-type ATPases	ATPase Na+/K+ transporting subunit alpha 3 ATPase cation transporting 13A2 Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Cardiac phospholamban Cation-transporting ATPase Cation-transporting ATPase EF-hand domain-containing protein FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator P-type Cu(+) transporter P-type Cu(+) transporter PDZ domain-containing protein 11 Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Potassium-transporting ATPase subunit beta Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Sorcin Uncharacterized protein calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase	A0A8I3MA13 A0A8I3MFG9 A0A8I3MFV6 A0A8I3MID3 A0A8I3MJQ7 A0A8I3MK29 A0A8I3MLP6 A0A8I3MM26 A0A8I3MMM6 A0A8I3MMW9 A0A8I3MQA1 A0A8I3MQM1 A0A8I3MRH3 A0A8I3MSQ7 A0A8I3NIS8 A0A8I3NMP2 A0A8I3NPB9 A0A8I3NTU5 A0A8I3NV67 A0A8I3NYA8 A0A8I3P728 A0A8I3PEN3 A0A8I3PJ46 A0A8I3PJZ4 A0A8I3PMF9 A0A8I3PQA5 A0A8I3PS86 A0A8I3PX21 A0A8I3PX80 A0A8I3PY73 A0A8I3Q2U7 A0A8I3Q6V0 A0A8I3QAS6 A0A8I3QPB8 A0A8I3RSR2 A0A8I3RUW2 A0A8I3RVD4 A0A8I3RWC7 A0A8I3RY81 A0A8I3S0A4 A0A8I3S140 A0A8I3S1T6 A0A8I3S4D0 A0A8I3S4P8 A0A8I3SBE1 A0A8I3SBK9 A0A8I3SCM5 O46674 P33704 P61012	ATP10A ATP10B ATP10D ATP11A ATP11B ATP11C ATP12A ATP13A1 ATP13A2 ATP13A4 ATP13A5 ATP1A1 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 ATP2C1 ATP2C2 ATP4A ATP4B ATP7A ATP7B ATP8A1 ATP8A2 ATP8B1 ATP8B2 ATP8B4 ATP9A ATP9B CALM2 CAMK2A CAMK2B CAMK2G FXYD1 FXYD2 FXYD3 FXYD4 FXYD6 FXYD7 PDZD11 PLN SRI
Transcriptional and post-translational regulation of MITF-M expression and activity	Adenosine 5'-monophosphoramidase HINT1 Adenosine 5'-monophosphoramidase HINT1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 Arginine--tRNA ligase, cytoplasmic Aspartate--tRNA ligase, cytoplasmic Deacetylase sirtuin-type domain-containing protein Eukaryotic translation elongation factor 1 epsilon 1 Exportin 1 Glutamyl-prolyl-tRNA synthetase 1 Glycogen synthase kinase-3 beta Kit ligand Lysine--tRNA ligase Mast/stem cell growth factor receptor Kit Melanocyte inducing transcription factor Methionine--tRNA ligase, cytoplasmic Mitogen-activated protein kinase Mitogen-activated protein kinase Protein Wnt T-box transcription factor 3 Transcription factor SOX-10 Uncharacterized protein glutamine--tRNA ligase histone acetyltransferase isoleucine--tRNA ligase leucine--tRNA ligase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A8I3M9Y6 A0A8I3ME48 A0A8I3MJJ8 A0A8I3MV00 A0A8I3MWK0 A0A8I3N265 A0A8I3NAU2 A0A8I3NB54 A0A8I3NDI5 A0A8I3NEL4 A0A8I3NFF8 A0A8I3NMM1 A0A8I3NNH1 A0A8I3P4F2 A0A8I3P666 A0A8I3PH02 A0A8I3PI46 A0A8I3PZP0 A0A8I3Q1I7 A0A8I3Q220 A0A8I3Q583 A0A8I3RQD0 A0A8I3RSP3 A0A8I3S702 A0A8I3SBI9 O97799 Q06220	AIMP1 AIMP2 AKT3 CREBBP DARS1 EEF1E1 EPRS1 GSK3B IARS1 KARS1 KIT KITLG LARS1 LOC100684571 MAPK1 MAPK3 MARS1 MGF MITF QARS1 RARS1 RPS6KA1 SIRT1 SOX10 TBX3 WNT3A XPO1
Stimuli-sensing channels	Acid sensing ion channel subunit 1 Acid sensing ion channel subunit 2 Acid sensing ion channel subunit 3 Acid sensing ion channel subunit family member 4 Acid sensing ion channel subunit family member 5 Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit beta Amiloride-sensitive sodium channel subunit gamma Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Aspartate beta-hydroxylase Barttin CLCNK type accessory subunit beta Bestrophin Bestrophin Bestrophin Bestrophin Calcium-activated chloride channel regulator 1 Chloride channel accessory 2 Chloride channel accessory 4 Chloride channel protein 1 Chloride channel protein 2 Chloride channel protein Chloride channel protein Chloride channel protein Chloride channel protein Chloride channel protein Chloride intracellular channel protein E3 ubiquitin-protein ligase EF-hand domain-containing protein HECT-type E3 ubiquitin transferase Osteoclastogenesis associated transmembrane protein 1 Protein tweety homolog Protein tweety homolog Protein tweety homolog RAF proto-oncogene serine/threonine-protein kinase Ryanodine receptor 1 Ryanodine receptor 2 Ryanodine receptor 3 Serine/threonine-protein kinase Sgk1 Serum/glucocorticoid regulated kinase family, member 3 Sodium channel epithelial 1 subunit delta Sodium leak channel, non-selective Solute carrier family 17 member 3 Solute carrier family 9 member B1 Solute carrier family 9 member B2 Solute carrier family 9 member C2 (putative) Sorcin Stomatin like 3 Stomatin Triadin Two pore segment channel 1 Two pore segment channel 2 Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Unc-79 homolog, NALCN channel complex subunit Unc-80 homolog, NALCN channel complex subunit peptidylprolyl isomerase	A0A8I3M9N6 A0A8I3MIG8 A0A8I3MK25 A0A8I3MKE6 A0A8I3MKT6 A0A8I3MMN5 A0A8I3MSQ7 A0A8I3MT21 A0A8I3MUX4 A0A8I3MXS3 A0A8I3N0C5 A0A8I3N0E7 A0A8I3N106 A0A8I3N6S0 A0A8I3N726 A0A8I3NAC3 A0A8I3NFB9 A0A8I3NH80 A0A8I3NHZ8 A0A8I3NKC4 A0A8I3NSX7 A0A8I3NUI9 A0A8I3NXW9 A0A8I3NYL1 A0A8I3P370 A0A8I3P4T9 A0A8I3P560 A0A8I3P659 A0A8I3P6A5 A0A8I3P7M3 A0A8I3P948 A0A8I3PAS7 A0A8I3PCD4 A0A8I3PDN2 A0A8I3PET1 A0A8I3PGN5 A0A8I3PJ01 A0A8I3PJ21 A0A8I3PJD4 A0A8I3PNF9 A0A8I3PP54 A0A8I3PRH5 A0A8I3PSM5 A0A8I3PV66 A0A8I3PY43 A0A8I3PZA0 A0A8I3Q0B9 A0A8I3Q0M9 A0A8I3Q2P4 A0A8I3Q383 A0A8I3Q4Q6 A0A8I3Q679 A0A8I3Q886 A0A8I3Q8P6 A0A8I3Q8R4 A0A8I3QA03 A0A8I3QXX9 A0A8I3QYD0 A0A8I3RQJ2 A0A8I3RSF1 A0A8I3RW06 A0A8I3RY81 A0A8I3RZ58 A0A8I3S651 A0A8I3SA78 P63050 Q9MZT1	ANO1 ANO2 ANO3 ANO4 ANO5 ANO6 ANO7 ANO8 ANO9 ASIC1 ASIC2 ASIC3 ASIC4 ASIC5 ASPH BEST1 BEST2 BEST3 BEST4 BSND CALM2 CLCA1 CLCA2 CLCA4 CLCN1 CLCN2 CLCN4 CLCN5 CLCN6 CLCN7 CLCNK CLCNKA CLIC2 LOC119880472 NALCN NEDD4L OSTM1 RAF1 RPS27A RYR1 RYR2 RYR3 SCNN1A SCNN1B SCNN1D SCNN1G SGK1 SGK3 SLC17A2 SLC9B1 SLC9B2 SLC9C2 SRI STOM STOML3 TPCN1 TPCN2 TRDN TTYH1 TTYH2 TTYH3 UBA52 UBB UBC UBCEP2 UNC79 UNC80 WWP1
Ion homeostasis	ATP binding cassette subfamily C member 9 ATP-sensitive inward rectifier potassium channel 11 ATPase Na+/K+ transporting subunit alpha 3 Adenosylhomocysteinase like 1 Aspartate beta-hydroxylase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Cardiac phospholamban Chloride intracellular channel protein EF-hand domain-containing protein FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Nitric oxide synthase 1 Ryanodine receptor 1 Ryanodine receptor 2 Ryanodine receptor 3 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Short transient receptor potential channel 1 Sodium/calcium exchanger 1 Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Solute carrier family 8 member A2 Solute carrier family 8 member A3 Sorcin Stromal interaction molecule 1 Triadin Troponin I, cardiac muscle cAMP-dependent protein kinase catalytic subunit alpha calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase peptidylprolyl isomerase	A0A8I3M9N6 A0A8I3MFG9 A0A8I3MID3 A0A8I3MJQ7 A0A8I3MK29 A0A8I3MM26 A0A8I3MQA1 A0A8I3MRH3 A0A8I3MSQ7 A0A8I3MSS1 A0A8I3MT21 A0A8I3MTJ5 A0A8I3MXS3 A0A8I3NIS8 A0A8I3NKB2 A0A8I3NMP2 A0A8I3NNW7 A0A8I3NVA4 A0A8I3NYA8 A0A8I3P560 A0A8I3PCD4 A0A8I3PEN3 A0A8I3PJ46 A0A8I3PQA5 A0A8I3PRW9 A0A8I3PT17 A0A8I3PW88 A0A8I3PX80 A0A8I3Q281 A0A8I3Q2P2 A0A8I3Q886 A0A8I3Q8P6 A0A8I3QAS6 A0A8I3RSR2 A0A8I3RTF4 A0A8I3RVD4 A0A8I3RWC7 A0A8I3RWM0 A0A8I3RY81 A0A8I3S0A4 A0A8I3SBE1 A0A8I3SBK9 O46674 P23685 P61012 Q8MKD5	ABCC9 AHCYL1 ASPH ATP1A1 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 CALM2 CAMK2A CAMK2B CAMK2G CLIC2 FXYD1 FXYD2 FXYD3 FXYD4 FXYD6 FXYD7 ITPR1 ITPR2 ITPR3 KCNJ11 LOC119880472 NCX1 NOS1 PLN PRKACA RYR1 RYR2 RYR3 SLC8A1 SLC8A2 SLC8A3 SRI STIM1 TNNI3 TRDN TRPC1
Ub-specific processing proteases	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ADRM1 26S proteasome ubiquitin receptor Androgen receptor Ataxin 7 Axin 2 Axin-1 Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 Beclin-1 Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 Cell division cycle 20 Cellular tumor antigen p53 Centriolar coiled-coil protein 110 Claspin Cyclin-A1 Cyclin-A2 Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator DNA polymerase E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Farnesylated proteins-converting enzyme 2 Forkhead box O4 GATA binding protein 3 Hepatocyte growth factor-regulated tyrosine kinase substrate Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Hypoxia-inducible factor 1-alpha Insulin degrading enzyme Interleukin-33 Kelch-like ECH-associated protein 1 M-phase inducer phosphatase Methionine adenosyltransferase 2 subunit beta Mitochondrial Rho GTPase Mitochondrial import receptor subunit TOM20 homolog Mitogen-activated protein kinase kinase kinase 7 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Myc proto-oncogene protein NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Non-selective voltage-gated ion channel VDAC1 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Protein Mdm4 RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RNA helicase Receptor interacting serine/threonine kinase 1 Ring finger protein 128 RuvB-like helicase SDS3 homolog, SIN3A corepressor complex component Signal transducing adaptor molecule 2 TATA-box binding protein associated factor 9b TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta receptor type-1 TNF receptor-associated factor 6 TNF receptor-associated factor Tankyrase 2 Transcription initiation factor TFIID subunit 10 Transcriptional adapter 3 Transcriptional adapter Transformation/transcription domain associated protein Translocase of outer mitochondrial membrane 70 USP domain-containing protein Ubiquitin B Ubiquitin carboxyl-terminal hydrolase 16 Ubiquitin carboxyl-terminal hydrolase 37 Ubiquitin carboxyl-terminal hydrolase 47 Ubiquitin carboxyl-terminal hydrolase 48 Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin specific peptidase 42 Ubiquitin thioesterase Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Voltage-dependent anion-selective channel protein 2 Voltage-dependent anion-selective channel protein 3 WD repeat domain 20 WD repeat-containing protein 48 histone acetyltransferase peptidyl-tRNA hydrolase peptidylprolyl isomerase ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A7R7V602 A0A8I3MC37 A0A8I3MCW5 A0A8I3MDM0 A0A8I3MDQ5 A0A8I3MFT9 A0A8I3MJQ1 A0A8I3MKL2 A0A8I3MKL4 A0A8I3MMN5 A0A8I3MNI0 A0A8I3MPG9 A0A8I3MQC7 A0A8I3MR89 A0A8I3MRP8 A0A8I3MSL4 A0A8I3MWJ0 A0A8I3MWQ7 A0A8I3MZA5 A0A8I3N0P1 A0A8I3N165 A0A8I3N2P0 A0A8I3N371 A0A8I3N3A0 A0A8I3N3R0 A0A8I3N3S4 A0A8I3N5F1 A0A8I3N683 A0A8I3N6Q2 A0A8I3N7L6 A0A8I3N7R6 A0A8I3N9G3 A0A8I3NA81 A0A8I3NAP2 A0A8I3NAV8 A0A8I3NBQ5 A0A8I3NDB6 A0A8I3NEM9 A0A8I3NFB9 A0A8I3NGD3 A0A8I3NGL0 A0A8I3NGV0 A0A8I3NH42 A0A8I3NH60 A0A8I3NHL8 A0A8I3NLI9 A0A8I3NM89 A0A8I3NMN1 A0A8I3NN65 A0A8I3NNJ9 A0A8I3NP66 A0A8I3NP69 A0A8I3NPX1 A0A8I3NR70 A0A8I3NRK8 A0A8I3NUC6 A0A8I3NUT4 A0A8I3NV88 A0A8I3NW63 A0A8I3NW81 A0A8I3NWA6 A0A8I3NXK9 A0A8I3NY77 A0A8I3NYC7 A0A8I3NYE9 A0A8I3NYK2 A0A8I3NZ86 A0A8I3P0Y8 A0A8I3P135 A0A8I3P2V4 A0A8I3P616 A0A8I3P6B7 A0A8I3P6G1 A0A8I3P6J5 A0A8I3P738 A0A8I3P7J9 A0A8I3P9V4 A0A8I3PB52 A0A8I3PBB2 A0A8I3PCC0 A0A8I3PCE5 A0A8I3PCI4 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PE84 A0A8I3PF55 A0A8I3PFL3 A0A8I3PG60 A0A8I3PGG8 A0A8I3PHC7 A0A8I3PI05 A0A8I3PJL4 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PLL0 A0A8I3PMH0 A0A8I3PNU1 A0A8I3PQ44 A0A8I3PQ52 A0A8I3PQD9 A0A8I3PU69 A0A8I3PVR3 A0A8I3PW10 A0A8I3PWL6 A0A8I3PWM3 A0A8I3PWW2 A0A8I3PX43 A0A8I3PY49 A0A8I3PYV8 A0A8I3PZ26 A0A8I3PZ42 A0A8I3PZ96 A0A8I3PZT2 A0A8I3Q0K8 A0A8I3Q3S2 A0A8I3Q4M1 A0A8I3Q5J1 A0A8I3Q610 A0A8I3Q7Y0 A0A8I3Q883 A0A8I3QA55 A0A8I3QBV9 A0A8I3QCQ3 A0A8I3QV78 A0A8I3QYD0 A0A8I3RP35 A0A8I3RRR7 A0A8I3RS56 A0A8I3RSX0 A0A8I3RT18 A0A8I3RT39 A0A8I3RV68 A0A8I3RVA5 A0A8I3RWV3 A0A8I3RWY9 A0A8I3RXL5 A0A8I3RXS6 A0A8I3RXV3 A0A8I3RZ76 A0A8I3RZD9 A0A8I3RZF8 A0A8I3RZQ8 A0A8I3S1Z6 A0A8I3S2L7 A0A8I3S2R9 A0A8I3S3G6 A0A8I3S4J6 A0A8I3S4R5 A0A8I3S6C6 A0A8I3S6H8 A0A8I3S6Q5 A0A8I3S789 A0A8I3S792 A0A8I3S794 A0A8I3S7M5 A0A8I3S9E1 A0A8I3S9T4 A0A8I3SCL5 A1E2V0 D2YYC0 E2RK09 E7FIY6 H9GWB1 J9P6S8 O97863 P56950 P60483 P63050 Q5U820	ABCC7 ADRB2 ADRM1 AR ARRB1 ARRB2 ATXN7 AXIN1 AXIN2 BECN1 BIRC2 BIRC3 CCNA1 CCNA2 CCP110 CDC20 CDC25A CDK16 CFTR CLSPN CYLD FKBP8 FOXO4 GATA3 H2AC1 H2AC13 H2AC14 H2AC16 H2AC19 H2AC21 H2AC25 H2AC4 H2AC6 H2BC10 H2BC15 H2BC2 H2BC21 H2BC26 H2BC3 HGS HIF1A IDE IFIH1 IKBKG IL33 KAT2A KEAP1 LOC100686569 LOC100687259 LOC100688437 LOC119867694 LOC119867696 LOC119867718 LOC119868881 LOC119869165 LOC119869175 LOC119869178 LOC119869187 LOC119869258 LOC119874734 LOC482940 MAP3K7 MAT2B MDM2 MDM4 MMAC1 MUL1 MYC Madh3 NFKBIA OTUB1 POLB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMB1 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTEN PTRH2 RCE1 RHOT1 RIPK1 RNF123 RNF128 RNF146 RPS27A RUVBL1 SIAH2 SMAD1 SMAD2 SMAD3 SMAD7 SMURF2 STAM2 SUDS3 TAB1 TADA2B TADA3 TAF10 TAF9B TGFBR1 TNKS TNKS2 TOMM20 TOMM70 TP53 TRAF2 TRAF6 TRRAP UBA52 UBB UBC UBCEP2 USP10 USP12 USP13 USP14 USP15 USP16 USP18 USP19 USP2 USP20 USP21 USP22 USP26 USP28 USP3 USP30 USP33 USP34 USP37 USP4 USP42 USP44 USP47 USP48 USP49 USP5 USP7 USP8 VDAC1 VDAC2 VDAC3 WDR20 WDR48 p53
Signaling by BMP	Bone morphogenetic protein 10 Bone morphogenetic protein 2 Cerberus 1, DAN family BMP antagonist Chordin like 1 E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Follistatin-related protein 1 Gremlin Growth differentiation factor 2 Inhibin alpha chain Inhibin beta A chain Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Noggin Serine/threonine-protein kinase receptor Serine/threonine-protein kinase receptor Ski oncogene Transforming growth factor beta receptor 3 Ubiquitin conjugating enzyme E2 D3 Zinc finger FYVE domain-containing protein receptor protein serine/threonine kinase receptor protein serine/threonine kinase receptor protein serine/threonine kinase receptor protein serine/threonine kinase	A0A7I8AUV5 A0A8I3MLM6 A0A8I3MRS8 A0A8I3MVJ8 A0A8I3N281 A0A8I3N723 A0A8I3N8R4 A0A8I3NCV3 A0A8I3NHH0 A0A8I3NM89 A0A8I3NU17 A0A8I3NW84 A0A8I3NYK2 A0A8I3NZI6 A0A8I3P2D1 A0A8I3P2Y0 A0A8I3P330 A0A8I3P4Q9 A0A8I3PB34 A0A8I3PG53 A0A8I3PG60 A0A8I3PPQ3 A0A8I3PZR5 A0A8I3Q270 A0A8I3QCM6 A0A8I3RR80 A0A8I3S5B1 A0A8I3S5W5 A0A8I3SCQ0	ACVR2A ACVR2B ACVRL1 BMP10 BMP2 BMPR1A BMPR1B BMPR2 CER1 CHRDL1 FSTL1 GDF2 GREM2 INHA INHBA NOG SKI SMAD1 SMAD4 SMAD5 SMAD6 SMAD7 SMAD9 SMURF1 SMURF2 TGFBR3 UBE2D1 UBE2D3 ZFYVE16
Activation of Matrix Metalloproteinases	72 kDa type IV collagenase Cathepsin G Chymase Chymotrypsinogen 2 Collagen type XVIII alpha 1 chain Collagenase 3 Elastase, neutrophil expressed Kallikrein 1 Kallikrein B1 Kallikrein-related peptidase 2 Matrix metallopeptidase 11 Matrix metallopeptidase 15 Matrix metallopeptidase 16 Matrix metallopeptidase 17 Matrix metallopeptidase 24 Matrix metallopeptidase 25 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Metalloproteinase inhibitor 1 Metalloproteinase inhibitor 2 Peptidase S1 domain-containing protein Plasminogen Procathepsin L SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 Stromelysin-1 Tryptase furin interstitial collagenase trypsin	A0A5K1VKB9 A0A8I3MCQ8 A0A8I3MF27 A0A8I3MGS0 A0A8I3MN73 A0A8I3MND9 A0A8I3MSY3 A0A8I3MWY2 A0A8I3MXC2 A0A8I3N1T9 A0A8I3N597 A0A8I3NK04 A0A8I3NM17 A0A8I3NXG0 A0A8I3P478 A0A8I3P5C4 A0A8I3PD99 A0A8I3PHE2 A0A8I3PMD6 A0A8I3PZ83 A0A8I3Q4H4 A0A8I3RPH1 A0A8I3S0N4 A0A8I3S3N5 P04813 P15944 P21842 Q6Y4Q5 Q8MJD1 Q9GL24 Q9TTY1	CMA1 COL18A1 CTRB CTRB1 CTSG CTSL CTSL1 ELA2 ELANE FURIN KLK1 KLK2 KLKB1 MMP1 MMP11 MMP13 MMP14 MMP15 MMP16 MMP17 MMP2 MMP24 MMP25 MMP3 MMP7 MMP8 MMP9 PLG PRSS2 SPOCK3 TIMP1 TIMP2
Post-translational modification: synthesis of GPI-anchored proteins	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase Alkaline phosphatase Alkaline phosphatase CAMPATH-1 antigen CD109 molecule CEA cell adhesion molecule 1 CEA cell adhesion molecule 20 Carboxypeptidase M Contactin-5 Glycoprotein 2 Hemicentin 2 IZUMO1 receptor, JUNO Ig-like domain-containing protein LY6/PLAUR domain containing 1 LY6/PLAUR domain containing 3 LY6/PLAUR domain containing 4 LY6/PLAUR domain containing 5 LY6/PLAUR domain containing 6B Limbic system associated membrane protein Low affinity immunoglobulin gamma Fc region receptor III-A Low affinity immunoglobulin gamma Fc region receptor III-A Lymphocyte antigen 6 family member G6C Lymphocyte antigen 6 family member G6D Melanotransferrin NAD(P)(+)--arginine ADP-ribosyltransferase NAD(P)(+)--arginine ADP-ribosyltransferase Neuritin 1 like Neuritin 1 Neuronal growth regulator 1 Neurotrimin Opioid binding protein/cell adhesion molecule like Otoancorin Pantetheinase Peptidase S1 domain-containing protein Phosphatidylinositol-glycan-specific phospholipase D Placenta-expressed transcript 1 protein Prion like protein doppel Prostate stem cell antigen Reticulon 4 receptor like 1 Reticulon 4 receptor like 2 Retinoic acid early-inducible protein 1 domain-containing protein Reversion inducing cysteine rich protein with kazal motifs Shadow of prion protein Sperm acrosome associated 4 Tectorin alpha Tectorin beta Testis expressed 101 Thy-1 membrane glycoprotein UPAR/Ly6 domain-containing protein UPAR/Ly6 domain-containing protein UPAR/Ly6 domain-containing protein UPAR/Ly6 domain-containing protein UPAR/Ly6 domain-containing protein Uncharacterized protein Uncharacterized protein X-prolyl aminopeptidase 2	A0A5F4D8V4 A0A8I3MAT6 A0A8I3MB16 A0A8I3MC73 A0A8I3MEX4 A0A8I3MFF6 A0A8I3MGB5 A0A8I3MHK2 A0A8I3MI32 A0A8I3MK32 A0A8I3MP74 A0A8I3MTL7 A0A8I3MTQ6 A0A8I3MTU9 A0A8I3MZC0 A0A8I3N367 A0A8I3N3V2 A0A8I3N6F5 A0A8I3NAY9 A0A8I3NFT9 A0A8I3NGU2 A0A8I3NH91 A0A8I3NIQ2 A0A8I3NJB5 A0A8I3NMI6 A0A8I3NNX5 A0A8I3NQP0 A0A8I3NTH0 A0A8I3NZ50 A0A8I3P0V6 A0A8I3P2N1 A0A8I3P2X9 A0A8I3P9X8 A0A8I3PBG0 A0A8I3PFN4 A0A8I3PK10 A0A8I3PNW6 A0A8I3PYZ3 A0A8I3Q1D0 A0A8I3Q7C6 A0A8I3Q8E3 A0A8I3QHH1 A0A8I3QN81 A0A8I3RRI7 A0A8I3RUJ8 A0A8I3RVF3 A0A8I3RW46 A0A8I3RXK7 A0A8I3RXW9 A0A8I3RYC5 A0A8I3RYX0 A0A8I3S2E0 A0A8I3S779 E2RP87 Q28896 Q9TSX8	ALPI ALPL ART3 ART4 BST1 CD109 CD52 CDW52 CE5 CEACAM1 CEACAM20 CNTN5 CPM FCGR3A GLIPR2 GP2 GPIHBP1 GPLD1 HMCN2 IZUMO1R LOC100683099 LOC119875695 LOC476816 LOC478984 LSAMP LY6D LY6E LY6G6C LY6G6D LY6H LYPD1 LYPD3 LYPD4 LYPD5 LYPD6B LYPD8 MELTF NEGR1 NRN1 NRN1L NTM OPCML OTOA PLET1 PRND PSCA RTN4RL1 RTN4RL2 SPACA4 SPRN TECTA TECTB TEX101 THY1 VNN1 XPNPEP2
Antimicrobial peptides	BPI fold containing family A member 2 BPI fold containing family B member 1 BPI fold containing family B member 2 BPI fold containing family B member 4 BPI fold containing family B member 6 BPI fold-containing family A member 1 Bactericidal permeability-increasing protein Cathelicidin Cathepsin G Chromogranin-A Elastase, neutrophil expressed Liver-expressed antimicrobial peptide 2 Lysozyme C, spleen isozyme Peptidase inhibitor 3 Peptidoglycan recognition protein 2 Peptidoglycan-recognition protein Rerating islet-derived 3 alpha Saposin B-type domain-containing protein trypsin	A0A5F4D5H8 A0A8I3MTX9 A0A8I3NJP0 A0A8I3NK04 A0A8I3NUZ6 A0A8I3PD99 A0A8I3PIK6 A0A8I3PIZ8 A0A8I3PJC6 A0A8I3PJT2 A0A8I3PMA8 A0A8I3PU85 A0A8I3S3D7 A0A8I3S705 D3DMB4 F1PZP0 P81709 Q6TN20 Q8MJD1	BPI BPIFA1 BPIFA2 BPIFB1 BPIFB2 BPIFB4 BPIFB6 CAMP CHGA CTSG ELA2 ELANE GNLY LEAP2 LOC100687463 PGLYRP1 PGLYRP2 PI3 PRSS2 REG3A	G49108TO
Keratinization	4Fe-4S ferredoxin-type domain-containing protein Desmocollin 1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoglein-3 Desmoplakin IF rod domain-containing protein Junction plakoglobin Keratin 12 Keratin 18 Keratin 23 Keratin 24 Keratin 26 Keratin 28 Keratin 32 Keratin 33B Keratin 35 Keratin 36 Keratin 39 Keratin 3 Keratin 40 Keratin 72 Keratin 73 Keratin 74 Keratin 75 Keratin 76 Keratin 77 Keratin 78 Keratin 80 Keratin 82 Keratin 84 Keratin 85 Keratin 9 Keratin associated protein 8-1 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 19 Keratin, type I cytoskeletal 20 Keratin, type I cytoskeletal 25 Keratin, type I cytoskeletal 27 Keratin, type II cytoskeletal 8 Keratin-associated protein 12-1-like Keratin-associated protein 9-3-like Keratin-associated protein Keratin-associated protein Keratin-associated protein Keratin-associated protein Plakophilin 1 Plakophilin 2 Plakophilin 3 Plakophilin 4 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A5F4CC19 A0A5F4CZ72 A0A8I3MUF8 A0A8I3MVK7 A0A8I3N105 A0A8I3N1J2 A0A8I3N5G6 A0A8I3NBY4 A0A8I3NCT2 A0A8I3NDC0 A0A8I3NEH7 A0A8I3NF36 A0A8I3NF93 A0A8I3NHU5 A0A8I3NIB1 A0A8I3NJG7 A0A8I3NJK2 A0A8I3NKA1 A0A8I3NKS4 A0A8I3NL10 A0A8I3NL87 A0A8I3NMX6 A0A8I3NNI9 A0A8I3NNW0 A0A8I3NPY5 A0A8I3NQB8 A0A8I3NQV4 A0A8I3NQY7 A0A8I3NS58 A0A8I3NSM8 A0A8I3NVV6 A0A8I3NXE8 A0A8I3NYA0 A0A8I3NZ03 A0A8I3P212 A0A8I3P7T0 A0A8I3P9A1 A0A8I3PD35 A0A8I3PD89 A0A8I3PEZ2 A0A8I3PG96 A0A8I3PJ84 A0A8I3PK78 A0A8I3PMV1 A0A8I3PPU4 A0A8I3PTF9 A0A8I3PUR6 A0A8I3PWA5 A0A8I3PWP6 A0A8I3PXA2 A0A8I3PYF6 A0A8I3Q1A4 A0A8I3Q1G9 A0A8I3Q2T7 A0A8I3QMH2 A0A8I3RW47 A0A8I3RXM1 A0A8I3RY38 A0A8I3RZQ2 A0A8I3S024 A0A8I3S0K7 A0A8I3S5Q3 A0A8I3S7M3 A0A8I3S850 A0A8I3S8A6 Q6EIZ0 Q7YRU7	DSC1 DSC3 DSG1 DSG2 DSG3 DSG4 DSP JUP KER10 KRT10 KRT12 KRT15 KRT18 KRT20 KRT23 KRT24 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT41 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT80 KRT81 KRT82 KRT83 KRT84 KRT85 KRT9 KRTAP11-1 KRTAP24-1 KRTAP3-1 KRTAP8-1 LOC100685322 LOC100685403 LOC100686265 LOC100686358 LOC102151268 LOC102151404 LOC102151604 LOC102151831 LOC102157302 LOC119873184 LOC610887 PKP1 PKP2 PKP3 PKP4
Costimulation by the CD28 family	B and T lymphocyte associated Growth factor receptor bound protein 2 Ig-like domain-containing protein Inducible T-cell costimulator Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 TNF receptor superfamily member 14 Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3P405 A0A8I3P519 A0A8I3P6Z0 A0A8I3PMT9 A0A8I3PT69 A0A8I3PWC6 A0A8I3Q857 A0A8I3S3N2 Q7YR73	AILIM BTLA GRB2 ICOS ICOSLG LOC100856339 PIK3CA PIK3R1 PIK3R2 PTPN11 PTPN6 TNFRSF14
IRS-mediated signalling	Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3NVW9 A0A8I3PWT3 A0A8I3S0I1 A0A8I3S3N2	IRS1 IRS2 PIK3CA PIK3CB PIK3R1 PIK3R2
MET activates PI3K/AKT signaling	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Phosphatidylinositol 3-kinase regulatory subunit alpha phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3NGY1 A0A8I3NXI8 A0A8I3PT69 Q867B7	GAB1 GRB2 HGF MET PIK3CA PIK3R1
Tie2 Signaling	Angiopoietin 4 Angiopoietin-1 Angiopoietin-2 Docking protein 2 GTPase HRas GTPase NRas Growth factor receptor bound protein 14 Growth factor receptor bound protein 2 Growth factor receptor bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase small monomeric GTPase	A0A5F4C2B1 A0A8I3N971 A0A8I3NC50 A0A8I3NID0 A0A8I3NM36 A0A8I3NUU1 A0A8I3NZA4 A0A8I3PMT9 A0A8I3PSP7 A0A8I3PT69 A0A8I3PWT3 A0A8I3PZB5 A0A8I3Q1A9 A0A8I3Q1I3 A0A8I3S0B4 A0A8I3S3D9 A0A8I3S3N2 A0A8J8	ANGPT1 ANGPT2 ANGPT4 DOK2 GRB14 GRB2 GRB7 HRAS KRAS NRAS PIK3CA PIK3CB PIK3R1 PIK3R2 PTPN11 SHC1 SOS1 TEK
Interleukin-3, Interleukin-5 and GM-CSF signaling	14-3-3 protein zeta/delta Colony stimulating factor 2 receptor subunit beta Fibronectin type-III domain-containing protein Granulocyte-macrophage colony-stimulating factor Interleukin 5 receptor subunit alpha Interleukin-3 Interleukin-5 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 SHC-transforming protein 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Vav guanine nucleotide exchange factor 1 cAMP-dependent protein kinase catalytic subunit alpha phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3N974 A0A8I3NA65 A0A8I3NBM3 A0A8I3NUU1 A0A8I3NVH4 A0A8I3P519 A0A8I3PBB4 A0A8I3PMT9 A0A8I3PRW9 A0A8I3PWC6 A0A8I3PWT3 A0A8I3Q4Y8 A0A8I3Q525 A0A8I3RVE7 A0A8I3RVV0 A0A8I3RX48 A0A8I3S3N2 P48749 Q95J76 Q9BDX4	CSF2 CSF2RA CSF2RB IL3 IL5 IL5RA JAK2 LOC100856339 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PRKACA PTPN11 PTPN6 SHC1 STAT5A STAT5B TEC VAV1 YWHAZ
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Adapter molecule crk BCAR1 scaffold protein, Cas family member CRK like proto-oncogene, adaptor protein Cytoplasmic protein Cytoplasmic protein GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Growth factor receptor bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B RAS p21 protein activator 1 Rap guanine nucleotide exchange factor 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase small monomeric GTPase	A0A5F4C2B1 A0A8I3N1K5 A0A8I3N488 A0A8I3N971 A0A8I3N974 A0A8I3NAN8 A0A8I3NEF4 A0A8I3NGQ0 A0A8I3NID0 A0A8I3P5F5 A0A8I3PDZ1 A0A8I3PMT9 A0A8I3PN08 A0A8I3PSA1 A0A8I3PSP7 A0A8I3PT69 A0A8I3PWT3 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3RV66 A0A8I3RVE7 A0A8I3RXB9 A0A8I3S3D9 A0A8I3S3N2 A0A8I3S602 A0A8I3S8J3 A0A8I3SBF9 A0A8I3SCI7 Q6Q7I7	BCAR1 CRK CRKL GRB2 GRB7 HRAS KRAS NCK1 NCK2 NRAS PDGFA PDGFB PDGFRA PDGFRB PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 PTPN11 RAPGEF1 RASA1 SOS1 SRC STAT1 STAT3 STAT5A STAT5B STAT6
Interleukin receptor SHC signaling	Colony stimulating factor 2 receptor subunit beta Fibronectin type-III domain-containing protein GRB2 associated binding protein 2 Granulocyte-macrophage colony-stimulating factor Growth factor receptor bound protein 2 Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Interleukin-3 Interleukin-5 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MVN6 A0A8I3N971 A0A8I3N9M7 A0A8I3NFE2 A0A8I3NUU1 A0A8I3NVH4 A0A8I3P519 A0A8I3PAP4 A0A8I3PBB4 A0A8I3PT69 A0A8I3PWC6 A0A8I3PWT3 A0A8I3Q525 A0A8I3RRY0 A0A8I3RS40 A0A8I3RVV0 A0A8I3RX48 A0A8I3S3D9 A0A8I3S3N2 A0A8I3S4Z2 P48749 Q29416 Q95J76 Q9BDX4	CSF2 CSF2RA CSF2RB GAB2 GRB2 IL2 IL2RA IL2RB IL3 IL5 IL5RA INPP5D INPPL1 JAK1 JAK2 JAK3 LOC100856339 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PTPN6 SHC1 SHIP2 SOS1
GPVI-mediated activation cascade	3-phosphoinositide-dependent protein kinase 1 C-type lectin domain-containing protein Cell division control protein 42 homolog High affinity immunoglobulin epsilon receptor subunit gamma Lymphocyte cytosolic protein 2 Megakaryocyte and platelet inhibitory receptor G6b Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide phospholipase C Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Phosphoinositide-3-kinase regulatory subunit 6 Podoplanin Rac family small GTPase 2 Ras homolog family member B Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 Transforming protein RhoA Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Vav guanine nucleotide exchange factor 1 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MGV8 A0A8I3MHV4 A0A8I3MMK3 A0A8I3MQX7 A0A8I3MY22 A0A8I3N060 A0A8I3N5M3 A0A8I3N971 A0A8I3NA65 A0A8I3NAC6 A0A8I3NC73 A0A8I3NEZ8 A0A8I3NH46 A0A8I3NHC2 A0A8I3NIT3 A0A8I3NZG2 A0A8I3P075 A0A8I3P3G0 A0A8I3P3X1 A0A8I3P519 A0A8I3PMT9 A0A8I3PUN0 A0A8I3PVV6 A0A8I3PWC6 A0A8I3PWT3 A0A8I3PY16 A0A8I3QSK6 A0A8I3S3N2 A0A8I3S601 P60952 P62999 Q95152	CDC42 CLEC1B FCER1G FYN GP40 GP6 LAT LCK LCP2 LOC100856339 LYN MPIG6B PDPK1 PDPN PIK3CA PIK3CB PIK3CG PIK3R1 PIK3R2 PIK3R5 PIK3R6 PLCG2 PTPN11 PTPN6 RAC1 RAC2 RHOA RHOB RHOG SYK VAV1 VAV2 VAV3
RET signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Docking protein 1 Docking protein 2 Docking protein 4 Docking protein 5 Docking protein 6 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha 4 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GRB2 associated binding protein 1 GRB2 associated binding protein 2 Glial cell derived neurotrophic factor Growth factor receptor bound protein 10 Growth factor receptor bound protein 2 Growth factor receptor bound protein 7 Insulin receptor substrate 2 Mitogen-activated protein kinase Neurturin PDZ and LIM domain protein 7 Persephin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Protein kinase C RAP1 GTPase activating protein Ret proto-onco SH3 and multiple ankyrin repeat domains 3 SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MGQ2 A0A8I3MHB6 A0A8I3MNH7 A0A8I3MVS5 A0A8I3N0M1 A0A8I3N7X4 A0A8I3N8L0 A0A8I3N971 A0A8I3N9M7 A0A8I3NBK6 A0A8I3NID0 A0A8I3NUU1 A0A8I3NXI8 A0A8I3P1P0 A0A8I3P4L9 A0A8I3P519 A0A8I3P721 A0A8I3PIF6 A0A8I3PMT9 A0A8I3PQ79 A0A8I3PRW9 A0A8I3PT69 A0A8I3PUQ8 A0A8I3PW06 A0A8I3PWT3 A0A8I3Q1A9 A0A8I3Q244 A0A8I3Q525 A0A8I3QCB4 A0A8I3QHK6 A0A8I3S0I1 A0A8I3S0X9 A0A8I3S3D9 A0A8I3S3N2 A0A8I3SBF9 A0A8I3SCI7 E2R534	DBN1 DOK1 DOK2 DOK4 DOK5 DOK6 FRS2 GAB1 GAB2 GDNF GFRA1 GFRA2 GFRA4 GRB10 GRB2 GRB7 IRS2 LOC100856339 MAPK7 NRTN PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PLCG1 PRKACA PRKACB PRKCA PSPN PTPN11 RAP1GAP RET SHANK3 SHC1 SHC3 SOS1 SRC

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