GlyCosmos Portal

Bos taurus (domestic cattle)

Summary

Taxonomy ID: 9913
PubChem Taxonomy: 9913

Genes (2200) Glycans (1011) Glycoproteins (1220) Lectins (76) Pathways (548)

Displaying entries **51 - 75** of **548** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Signal regulatory protein family interactions	FYB protein Growth factor receptor-bound protein 2 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Leukocyte surface antigen CD47 Signal regulatory protein alpha Src kinase-associated phosphoprotein 2 non-specific protein-tyrosine kinase	A0A3Q1LVP1 A0A3Q1M4J0 A0A3Q1MFX6 A0A3Q1NMT9 A7YWJ7 F1MRG6 F1MZ44 Q32LP7 Q3T0F9	CD47 FYB GRB2 PTK2B SCAP2 SIRPA SIRPB1 SKAP2
Negative regulation of the PI3K/AKT network	Phosphatase and tensin homolog	F1MDX9	PTEN
Acrosome Reaction and Sperm:Oocyte Membrane Binding	Acrosin CD9 antigen IZUMO family member 2 IZUMO family member 4 Izumo sperm-egg fusion protein 3 Izumo sperm-oocyte fusion 1	A6QL94 E1BC82 E1BDA8 F1MYA6 G5E5C6 P30932	ACR CD9 IZUMO1 IZUMO2 IZUMO3 IZUMO4
ABC-family proteins mediated transport	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily B member 1 ATP binding cassette subfamily B member 4 ATP binding cassette subfamily B member 9 ATP binding cassette subfamily C member 10 ATP binding cassette subfamily C member 11 ATP binding cassette subfamily C member 2 ATP binding cassette subfamily C member 4 ATP binding cassette subfamily C member 5 ATP binding cassette subfamily C member 9 ATP binding cassette subfamily F member 1 ATP-sensitive inward rectifier potassium channel 11 Cystic fibrosis transmembrane conductance regulator Derlin-1 Derlin Derlin E3 ubiquitin-protein ligase RNF E3 ubiquitin-protein ligase RNF Endoplasmic reticulum lectin Endoplasmic reticulum lectin Erlin-2 Erlin Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Multidrug resistance-associated protein 1 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta Proteasome subunit beta Retinal-specific phospholipid-transporting ATPase ABCA4 SEL1L adaptor subunit of ERAD E3 ubiquitin ligase Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LQI5 A0A3Q1LV78 A0A3Q1LZ87 A0A3Q1MB23 A0A3Q1ME24 A0A3Q1NB13 A1L5A6 A2VDS4 A4IFC2 A7MBA2 E1BLT5 E1BNL1 F1MBI1 F1MGJ5 F1MGK3 F1MIP7 F1MLV1 F1MN01 F1MS86 F1MUC1 F1MWE0 F1MWM0 F1MX65 F1MXE4 F1MYH8 F1MZD4 F1N3Y6 F1N4I6 F6PVF9 G3N0U8 G3X757 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 P68102 Q17QP9 Q1RMU4 Q2KHU8 Q2KI42 Q2KJ25 Q2KJ46 Q2YDE4 Q32KL2 Q3MHN0 Q3T030 Q3T0X5 Q3T0Y5 Q3T108 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9K0 Q71SS4 Q8HXQ5	ABCA4 ABCB1 ABCB4 ABCB9 ABCC1 ABCC10 ABCC11 ABCC2 ABCC3 ABCC5 ABCC9 ABCF1 ABCR ADRM1 CFTR DERL1 DERL2 DERL3 EIF2A EIF2S1 EIF2S2 EIF2S3 ERLEC1 ERLIN1 ERLIN2 KCNJ11 LOC515333 MRP1 OS9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RNF185 RNF5 RPS27A SEL1L SPFH2 SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Checkpoint kinase 2 M-phase inducer phosphatase 1 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta Proteasome subunit beta Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A1L5A6 A7MBA2 A7MBD1 F1MBI1 F1MLV1 F1MWE0 F1MXE4 F1MYH8 F6R5E4 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2YDE4 Q32KL2 Q3MHN0 Q3T030 Q3T0X5 Q3T0Y5 Q3T108 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9K0	ADRM1 CDC25A CHEK2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Classical antibody-mediated complement activation	Adiponectin B Complement C1q subcomponent subunit A Complement C1q subcomponent subunit B Complement C1s Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Pentraxin family member Uncharacterized protein complement subcomponent C1r	A0A3B0IZF8 A0A3Q1LKV0 A0A3Q1LPG0 A0A3Q1M3L6 A0A3Q1M7Q5 A0A3Q1MGP1 C4T8B4 G3N0V0 Q2KIV9 Q5E9E3	ADIB C1QA C1QB C1R C1S CRP
Cell surface interactions at the vascular wall	AMICA1 protein Apolipoprotein B C-X-C motif chemokine CD177 molecule CD2 molecule CD44 antigen CD48 molecule CD58 molecule CD74 molecule CD84 molecule Coxsackievirus and adenovirus receptor homolog E-selectin Endothelial cell adhesion molecule Endothelial protein C receptor Epithelial cell adhesion molecule Fc alpha and mu receptor Fibronectin Glypican-1 Golgi apparatus protein 1 Growth arrest specific 6 High affinity immunoglobulin epsilon receptor subunit gamma Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin J chain Immunoglobulin V-set domain-containing protein Immunoglobulin V-set domain-containing protein Integrin alpha-L Integrin beta-2 Integrin beta Integrin subunit alpha 4 Integrin subunit alpha M JAM2 protein Junctional adhesion molecule A Leukocyte surface antigen CD47 Macrophage migration inhibitory factor Oxidized low-density lipoprotein receptor 1 Platelet and endothelial cell adhesion molecule 1 Prothrombin SPN protein Signal regulatory protein alpha Syndecan-1 Syndecan-2 Syndecan Thrombomodulin Transforming growth factor beta-1 proprotein Triggering receptor expressed on myeloid cells 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase VWFA domain-containing protein Vitamin K-dependent protein C Vitamin K-dependent protein S p-selectin receptor protein-tyrosine kinase	A0A140T8D2 A0A3Q1LKV0 A0A3Q1LL67 A0A3Q1LX90 A0A3Q1LZ29 A0A3Q1LZT3 A0A3Q1M4J0 A0A3Q1M616 A0A3Q1M7Z2 A0A3Q1M8C4 A0A3Q1MBI9 A0A3Q1MEG8 A0A3Q1MFX6 A0A3Q1MHJ9 A0A3Q1MQ27 A0A3Q1N449 A0A3Q1NMT9 A0A452DI66 A0JNB0 A1L4Z7 A4IFI9 A6QPF9 A6QPH6 A6QQP5 E1B8L8 E1BF48 E1BKS1 E1BNR0 F1MD83 F1MEF6 F1MEP6 F1MQT9 F1MRG6 F1MZ40 F1MZ44 F1N261 F1N381 F1N7U9 F6PZJ9 G3MYD9 G5E5A9 P07224 P32592 P61625 P80177 P98107 Q08DZ5 Q148M9 Q28105 Q2KHZ6 Q2KJA9 Q3SYR8 Q58DD4 Q8WMV3 Q9BDR7 Q9XT56	AMICA1 APOB CAR CD177 CD18 CD2 CD44 CD47 CD48 CD58 CD74 CD84 CEACAM1 CXADR EPCAM EPCR ESAM F11R F2 FCAMR FCER1G FN1 FYN GAS6 GLG1 GPC1 IGJ ITGA4 ITGAL ITGAM ITGAX ITGB1 ITGB2 JAM1 JAM2 LOC112442324 LYN MERTK MIF OLR1 PECAM1 PPBP PROC PROCR PROS PROS1 SDC1 SDC2 SDC4 SELE SELP SIRPA SIRPB1 SPN TGFB1 THBD TREM1
Ion transport by P-type ATPases	ATPase 13A1 ATPase cation transporting 13A2 Calcium-transporting ATPase type 2C member 1 Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Cardiac phospholamban Cation-transporting ATPase Cation-transporting ATPase EF-hand domain-containing protein EF-hand domain-containing protein FXYD domain-containing ion transport regulator 6 FXYD domain-containing ion transport regulator 7 FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator Phospholemman Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Plasma membrane calcium-transporting ATPase 4 Probable phospholipid-transporting ATPase IIB Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sodium/potassium-transporting ATPase subunit alpha-1 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Sorcin calcium/calmodulin-dependent protein kinase	A0A3Q1LHA5 A0A3Q1LQ26 A0A3Q1LWV7 A0A3Q1LYD6 A0A3Q1M082 A0A3Q1M0A4 A0A3Q1M1C8 A0A3Q1M288 A0A3Q1M9U0 A0A3Q1MCF3 A0A3Q1MGH8 A0A3Q1MKC7 A0A3Q1MR28 A0A3Q1ND98 A1A4J6 A2VDL6 A6QLL5 D3K0R6 E1B8N5 E1BLX8 E1BMQ6 E1BNB9 E1BPC3 F1MF00 F1MFC4 F1MLH6 F1MMX5 F1MN60 F1MR06 F1MS16 F1MW32 F1MXW4 F1MYA8 F1MZ89 F1N272 F1N3G6 F1N7C2 F2Z4I4 F6QQY9 G3MWR4 P57709 Q08DA1 Q0VCY0 Q2HJF7 Q3MHJ9 Q3MHZ5 Q3SZX0 Q3T0C6 Q3ZBJ3	ATP10A ATP10B ATP10D ATP11A ATP11B ATP11C ATP12A ATP13A1 ATP13A2 ATP13A4 ATP13A5 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 ATP2C1 ATP2C2 ATP4A ATP4B ATP8A1 ATP8A2 ATP8B1 ATP8B2 ATP8B3 ATP8B4 ATP9A ATP9B CALM CAMK2A CAMK2B CAMK2D FXYD1 FXYD2 FXYD4 FXYD6 FXYD7 PLM PLN SPCA SRI
Glutathione synthesis and recycling	Cytosolic non-specific dipeptidase Gamma-glutamylcyclotransferase Gamma-glutamylcyclotransferase Glutamate--cysteine ligase regulatory subunit Glutamate--cysteine ligase Glutathione hydrolase 7 Glutathione hydrolase Glutathione hydrolase Glutathione synthetase Putative glutathione-specific gamma-glutamylcyclotransferase 2	A0A140T850 A0A3Q1MN33 A6H738 F1MYJ3 G3N2D8 Q0IIH4 Q0V8L2 Q2T9Y6 Q32LE4 Q3ZC84	CHAC1 CHAC2 CNDP2 GCLC GCLM GGCT GGT1 GGT5 GGT7 GGTL3 GSS
Clathrin-mediated endocytosis	ADP ribosylation factor GTPase activating protein 1 AP-1 complex subunit beta-1 AP-2 complex subunit alpha-2 AP-2 complex subunit alpha AP-2 complex subunit mu AP-2 complex subunit sigma AP2 associated kinase 1 Actin nucleation-promoting factor WASL Actin related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2 Actin-related protein 3 Adaptin ear-binding coat-associated protein 1 Amphiphysin Amphiregulin Apolipoprotein B Arginine vasopressin Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 Betacellulin Bridging integrator 1 CD4 molecule Cation-dependent mannose-6-phosphate receptor Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Cyclin G associated kinase Cystic fibrosis transmembrane conductance regulator DAB adaptor protein 2 Dishevelled segment polarity protein 2 DnaJ heat shock protein family (Hsp40) member C6 Dynamin-1 E3 ubiquitin-protein ligase CBL EPS15 protein Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 like 1 Epiregulin Epithelial mitogen Epsin 1 Epsin 2 F-BAR domain only protein 2 FCH and mu domain containing endocytic adaptor 1 Formin binding protein 1 Formin-binding protein 1-like GTPase-activating protein and VPS9 domain-containing protein 1 Growth factor receptor-bound protein 2 Heat shock cognate 71 kDa protein Hepatocyte growth factor-regulated tyrosine kinase substrate Huntingtin interacting protein 1 related Huntingtin interacting protein 1 Insulin like growth factor 2 receptor Interleukin-7 receptor subunit alpha Intersectin 1 Intersectin 2 KIAA0319 LDL receptor related protein 2 LDLRAP1 protein Low-density lipoprotein receptor Muscarinic acetylcholine receptor M2 NECAP endocytosis associated 2 Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma Polyubiquitin-B Polyubiquitin-C Proheparin-binding EGF-like growth factor Protein Wnt Protein kinase C and casein kinase substrate in neurons 2 Protein kinase C and casein kinase substrate in neurons 3 Protein kinase C and casein kinase substrate in neurons protein 1 RALBP1 associated Eps domain containing 1 Ras-related protein Rab-5A Receptor protein-tyrosine kinase SH3 domain containing GRB2 like 2, endophilin A1 SH3 domain containing GRB2 like 3, endophilin A3 SH3 domain containing kinase binding protein 1 Scavenger receptor class B member 2 Serotransferrin Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Solute carrier family 18 member A3 Solute carrier family 2 member 8 Sorting nexin Sorting nexin Stonin-1 Stonin-2 Substance-P receptor Synaptosome associated protein 91 Synaptotagmin 11 Synaptotagmin 8 Synaptotagmin 9 Synaptotagmin-1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 gamma chain Thyroid hormone receptor interactor 10 Trans-golgi network protein 2 Transferrin receptor protein 1 Transforming growth factor alpha Type-1 angiotensin II receptor Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vasopressin V2 receptor Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 4 Vesicle-associated membrane protein 8 dynamin GTPase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase small monomeric GTPase	A0A3Q1LK58 A0A3Q1LN00 A0A3Q1LPM3 A0A3Q1LVF9 A0A3Q1LXE7 A0A3Q1LXY0 A0A3Q1M7J4 A0A3Q1M808 A0A3Q1M839 A0A3Q1MAH6 A0A3Q1MBL1 A0A3Q1MG95 A0A3Q1MHB0 A0A3Q1MIC9 A0A3Q1MKW3 A0A3Q1ML18 A0A3Q1MMI6 A0A3Q1MSK9 A0A3Q1MSZ4 A0A3Q1MWJ5 A0A3Q1NNG9 A0A3S5ZPN6 A2VDU0 A2VE27 A4IFN6 A4IFV0 A5D794 A5D7I1 A7MB62 A7MBI0 E1BBE2 E1BDG5 E1BDM2 E1BDP2 E1BE68 E1BIG6 E1BIN8 E1BJ14 E1BK36 E1BK71 E1BKY4 E1BNR0 E1BPM3 F1MBY5 F1MC50 F1MEV4 F1MGT4 F1MI54 F1MIB2 F1MIE6 F1MIX5 F1MJK4 F1MN01 F1MNI4 F1MRS2 F1MSM9 F1MUI0 F1MWF0 F1MX23 F1MZ25 F1MZY9 F1N1U1 F1N371 F1N4I2 F1N579 F1N6H1 F1N6W6 F6Q4T4 F6RJ01 F6RS49 G3MXC8 G3X6N3 G3X811 G8JL01 P01131 P04973 P04975 P0CG53 P0CH28 P11456 P17870 P19120 P25104 P41985 P48018 P48044 P49951 P61157 P62992 P63026 P63048 Q08DF4 Q08DS7 Q08DX1 Q0IIG7 Q0V8S0 Q0VCK5 Q148J6 Q17QC5 Q1JP79 Q1RMR9 Q28044 Q28072 Q2KJA1 Q32L97 Q3MHR7 Q3T035 Q3T093 Q3T0F9 Q3T0Y8 Q3ZC13 Q95107	AAK1 ACTR2 ACTR3 ADRB2 AGTR1 AMPH AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB AREG ARFGAP1 ARP2 ARP3 ARPC1A ARPC2 ARPC3 ARPC4 ARPC5 ARRB1 ARRB2 AVP AVPR2 BIN1 BTC CBL CD3D CD3G CD4 CFTR CHRM2 CLTA CLTB CLTC CLTLB DAB2 DNAJC6 DNM1 DNM3 DVL2 EGFR EPGN EPN1 EPN2 EPS15 EPS15L1 EREG FCHO1 FCHO2 FNBP1 FNBP1L GAK GAPVD1 GRB2 HBEGF HGS HIP1 HIP1R HSC70 HSPA8 IGF2R IL7R ITSN1 ITSN2 KIAA0319 LDLR LDLRAP1 LRP2 M6PR NECAP1 NECAP2 OCRL PACSIN1 PACSIN2 PACSIN3 PIK3C2A PIP5K1C RAB5A RAB5B REPS1 RPS27A SCARB2 SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SLC18A3 SLC2A8 SNAP91 SNX18 SNX9 STAM STAM2 STON1 STON2 SYB2 SYNJ2 SYT1 SYT11 SYT8 SYT9 TACR1 TF TFRC TGFA TRIP10 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VAMP2 VAMP4 VAMP8 WASL WNT5A
Mitochondrial unfolded protein response (UPRmt)	DnaJ homolog subfamily A member 1 Estrogen receptor Forkhead box O3 Heat shock 70 kDa protein 1A Heat shock factor protein 1 NAD-dependent protein deacetylase	F1N4K5 G5E521 P49884 Q08DJ8 Q27975 Q5E954	DNAJA1 ESR ESR1 FOXO3 HSF1 HSP70-1 HSPA1A NR3A1 SIRT3
SHC-related events triggered by IGF1R	Growth factor receptor-bound protein 2 Insulin-like growth factor I Insulin-like growth factor II SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	F1N7C3 G1K218 P07455 P07456 Q0IIE2 Q3T0F9	GRB2 IGF1 IGF1R IGF2 SHC1 SOS1
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-B Polyubiquitin-C SMAD family member 7 Serine-threonine kinase receptor-associated protein TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase	A0A3Q1LHW5 A0A3Q1LJ39 A0A3Q1N449 E1B7G3 E1B8T7 E1BE92 F1MUZ3 G3MZV8 O46680 P0CG53 P0CH28 P62992 P63048 Q1RMX1 Q5E959	BAMBI MTMR4 RPS27A SMAD2 SMAD3 SMAD7 SMURF2 STRAP STUB1 TGFB1 TGFBR1 TGFBR2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Acyl chain remodelling of PI	Cytosolic phospholipase A2 LRAT domain-containing protein Lysophospholipid acyltransferase 7 PLA2G12A protein Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like 1 Secretory phospholipase A2 receptor	A0A3Q1LYR5 A0A3Q1MNU5 A0A3Q1NMD6 A4IFJ5 A5D7L0 E1BGU4 F1MG30 F1MNU5 F1MSG5 P00593 P49259 Q0VCY6 Q56JZ2 Q9GL30	CPLA2 LENG4 LOC613966 MBOAT7 OACT7 PLA2G12A PLA2G16 PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G4 PLA2G4A PLA2G4D PLA2G4E PLA2G4F PLA2R1 PLBD1
RAC3 GTPase cycle	Abl interactor 1 Abl interactor 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Active breakpoint cluster region-related protein Adhesion molecule with Ig like domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 BAR/IMD domain containing adaptor protein 2 like 1 BAR/IMD domain-containing adapter protein 2 BCR activator of RhoGEF and GTPase C22H3ORF10 protein Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein DEP domain containing 1B Dedicator of cytokinesis 10 Delta(14)-sterol reductase LBR Delta-like protein Desmoglein 2 Diaphanous related formin 3 EMD protein Endoplasmic reticulum protein 27 FERM domain containing kindlin 2 Family with sequence similarity 62 (C2 domain containing), member A GIT ArfGAP 1 GIT ArfGAP 2 Granule associated Rac and RHOG effector 1 HSPC321 protein Integrin beta Lectin, mannose binding 1 MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase organizer 1 NCK associated protein 1 like NHS actin remodeling regulator Neutral amino acid transporter B(0) Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Progesterone receptor membrane component 2 RAC3 protein RNA binding motif protein 39 Rac GTPase activating protein 1 Ragulator complex protein LAMTOR1 Rap guanine nucleotide exchange factor 1 Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 42 Rho GTPase activating protein 5 Rho GTPase activating protein 6 Rho GTPase-activating protein 15 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 SLIT and NTRK like family member 3 SLIT and NTRK like family member 5 SLIT-ROBO Rho GTPase activating protein 2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase TAO3 Starch binding domain 1 Synapse defective Rho GTPase homolog 1 Synaptobrevin homolog YKT6 Synaptosomal-associated protein Transferrin receptor protein 1 Tyrosine-protein kinase Vang-like protein Vav guanine nucleotide exchange factor 2 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase p21 protein (Cdc42/Rac)-activated kinase 4 phosphoinositide 5-phosphatase receptor protein-tyrosine kinase	A0A140T8D2 A0A3Q1LLI7 A0A3Q1LMM5 A0A3Q1LNB6 A0A3Q1LPH8 A0A3Q1LWV5 A0A3Q1LWZ4 A0A3Q1LXN8 A0A3Q1M0G8 A0A3Q1M4M7 A0A3Q1M7Q3 A0A3Q1MKI4 A0A3Q1MP86 A0A3Q1MQK6 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MSA1 A0A3Q1MT43 A0A3Q1MTW8 A0A3Q1N078 A0A3Q1N6J8 A0A452DHY1 A0A452DIS6 A0JN43 A2VDK6 A4IF90 A5PK69 A6H709 A6QNS3 A6QQV8 A6QQZ7 A7MB21 A8YXX8 E1B7C4 E1B801 E1B876 E1B8X9 E1BAA4 E1BAJ4 E1BBA0 E1BDN7 E1BFF3 E1BGL2 E1BHQ9 E1BI41 E1BIG6 E1BJ31 E1BJP2 E1BLB3 E1BM23 E1BMN2 E1BN47 E1BNR7 E1BPJ7 F1MBY5 F1MFC2 F1MLS2 F1MTN6 F1MWH1 F1MWH8 F1MXR0 F1MXU4 F1N1Q7 F1N348 F1N513 F1N6V1 F1N7Q8 F6QJJ8 F6RWK1 O46521 O46522 P23726 P23727 P79132 Q08E52 Q0IIJ3 Q17QW1 Q17QZ0 Q2KJ93 Q2T9M8 Q3SX08 Q3T000 Q3T0D8 Q5EAD0 Q95JC7	ABI1 ABI2 ABL2 ABR AMIGO2 ARAP2 ARAP3 ARHGAP1 ARHGAP15 ARHGAP17 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP42 ARHGAP5 ARHGAP6 ARHGDIB ASCT2 BAIAP2 BAIAP2L1 BCR BORG5 C22H3ORF10 CAV1 CDC42 CDC42EP1 CYBA CYBB CYFIP1 DEPDC1B DIAPH3 DOCK10 DSG2 EMD EPHA2 ERP27 FAM62A FERMT2 GARRE1 GIT1 GIT2 HSPC321 ITGB1 JAG1 LAMTOR1 LBR LMAN1 MCAM MPP7 NCF1 NCF2 NCF4 NCKAP1L NHS NOX1 NOX3 NOXO1 OCRL OPHN1 PAK1 PAK2 PAK4 PGRMC2 PIK3R1 PIK3R2 PREX1 RAC3 RACGAP1 RAPGEF1 RBM39 SLC1A5 SLITRK3 SLITRK5 SNAP23 SRGAP2 STBD1 SWAP70 SYDE1 TAOK3 TFRC TRIO VANGL1 VAV2 VRK2 WASF1 WASF2 YKT6
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Coagulation factor VIII Protein-S-isoprenylcysteine O-methyltransferase Protein-tyrosine sulfotransferase 2 Protein-tyrosine sulfotransferase protein-ribulosamine 3-kinase	G3N1V4 G5E5W1 Q08DH2 Q0P592 Q3SYY2	F8 FN3KRP ICMT TPST1 TPST2
TGF-beta receptor signaling activates SMADs	E3 ubiquitin-protein ligase CBL Integrin beta-6 Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha V Latent transforming growth factor beta binding protein 1 Latent transforming growth factor beta binding protein 2 Latent transforming growth factor beta binding protein 3 Latent transforming growth factor beta binding protein 4 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog NEDD8-conjugating enzyme Ubc12 NEDD8 Peptidyl-prolyl cis-trans isomerase FKBP1A TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta receptor 3 Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta Zinc finger FYVE domain-containing protein furin	A0A140T8D2 A0A3Q1LJU9 A0A3Q1LN00 A0A3Q1MXS2 A0A3Q1N449 A3KN22 A6QP91 B0JYL0 B0JYR0 E1B9H5 E1BE92 F1MF86 F1MKY4 F1MTN1 F1MUZ3 F1MVW3 F1N444 G3MZT8 G3MZV8 O46680 P18203 P21214 P61282 Q8SQB8 Q8SQB9	CBL FKBP1 FKBP1A FURIN ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP2 LTBP3 LTBP4 NEDD8 SMAD2 SMAD3 SMAD4 TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TGFBR3 UBC12 UBE2M ZFYVE9
Activation of C3 and C5	C4a anaphylatoxin Complement C2 Complement C3 Complement C5 Complement factor B Uncharacterized protein	E1BH06 F1MVK1 F1MY85 P81187 Q2UVX4 Q3SYW2	BF C2 C3 C4A C5 CFB LOC107131209
Pyroptosis	Apoptosis regulator BAX BCL2-antagonist/killer 1 CHMP4B protein Caspase 1 Caspase-13 Caspase-3 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 7 Chromatin modifying protein 4C Chromatin modifying protein 6 Cytochrome c Elastase, neutrophil expressed Gasdermin D Gasdermin E Granzyme B High mobility group protein B1 Interleukin-1 alpha Interleukin-18 Multifunctional fusion protein	A0A140T838 A0A3Q1MD51 A0A3Q1MFA5 A2VDY3 A6H704 E1BFC3 F1MB04 F1MTF4 G3MWP1 O02703 O75601 P08831 P10103 P62894 Q05KI7 Q08E32 Q148L0 Q2HJ35 Q3SX42 Q3T0U5 Q58CS7 Q9TU73	BAK1 BAX CASP1 CASP13 CASP3 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 CYC CYCS ELANE GSDMD GSDME GZMB HMG1 HMGB1 IGIF IL18 IL1A IL1B VPS24
SHC-mediated cascade:FGFR3	Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase NRas Growth factor receptor-bound protein 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A3Q1MPT9 A0MTF4 A5D7R9 D8KXU9 E1BJU2 E1BMX0 E1BP37 F1MHC6 F1N6G8 F1N7C3 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969 Q0IIE2 Q3T0F9	AFGF FGF1 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF4 FGF4A FGF4C FGF5 FGF6A FGF8 FGF9 FGFA FGFR3 Fgf4 GRB2 HBGF-1 KRAS NRAS SHC1 SOS1
Transport of inorganic cations/anions and amino acids/oligopeptides	Amino acid transporter Amino acid transporter Amino acid transporter Amino acid transporter Cystinosin Excitatory amino acid transporter 1 Mitochondrial S-adenosylmethionine carrier protein Vesicular inhibitory amino acid transporter	A0A3Q1MR13 A6H774 A6QR09 A7MB63 F1MJN4 F1MUT8 G3N354 P46411	CTNS EAAT1 GLAST GLAST1 SAMC SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC25A26 SLC32A1
Degradation of the extracellular matrix	72 kDa type IV collagenase A disintegrin and metalloproteinase with thrombospondin motifs 4 ADAM metallopeptidase domain 15 ADAM metallopeptidase with thrombospondin type 1 motif 5 Aggrecan core protein Basigin Brevican core protein CD44 antigen Cadherin-1 Calpain 10 Calpain 12 Calpain 13 Calpain 14 Calpain 5 Calpain 6 Calpain 7 Calpain 8 Calpain small subunit 1 Calpain-1 catalytic subunit Calpain-2 catalytic subunit Calpain-3 Calpastatin Cathepsin K Cathepsin S Collagenase 3 Decorin Disintegrin and metalloproteinase domain-containing protein 10 Elastase, neutrophil expressed HtrA serine peptidase 1 Kallikrein-related peptidase 7 Matrix metallopeptidase 12 Matrix metallopeptidase 19 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 NID1 protein Opticin Peptidase S1 domain-containing protein Procathepsin L Secreted phosphoprotein 1 Signal peptide, CUB domain and EGF like domain containing 1 Signal peptide, CUB domain and EGF like domain containing 3 Stromelysin-1 Transmembrane serine protease 6 interstitial collagenase	A0A3Q1LJS3 A0A3Q1LZU0 A0A3Q1M4A6 A0A3Q1MG91 A0A3Q1MSS6 A0A3Q1MZC5 A0A452DI93 A0A452DJ01 A6QNS6 A6QP82 E1BAD2 E1BI66 E1BIX3 E1BJ18 E1BKJ3 F1MB09 F1MBN8 F1MJF1 F1MKH8 F1MQ31 F1MQD1 F1MQT9 F1MRZ2 F1MT97 F1MTX6 F1MU56 F1MW26 F1MWW8 F1N121 F1N1E3 F1N368 F6RFP6 G3MWP1 G3N0J0 G8JKX1 P13135 P21793 P25326 P25975 P52176 P58874 Q08D90 Q08DI9 Q10741 Q27971 Q5E968	ACAN ADAM10 ADAM15 ADAMTS4 ADAMTS5 BCAN BSG CAPN1 CAPN10 CAPN12 CAPN13 CAPN14 CAPN2 CAPN3 CAPN4 CAPN5 CAPN6 CAPN7 CAPN8 CAPNS1 CAST CD44 CDH1 CTSK CTSL CTSL1 CTSS DCN ELANE HTRA1 KLK7 LOC112441463 LOC509956 MADM MMP12 MMP13 MMP14 MMP19 MMP2 MMP3 MMP7 MMP8 MMP9 NID1 OPT OPTC SCUBE1 SCUBE3 SPP1 TMPRSS6
Regulation of CDH11 function	ADAM metallopeptidase domain 19 ADAM metallopeptidase domain 33 Angiomotin Angiopoietin-related protein 4 Cadherin 11 Catenin beta-1 Catenin delta 1 Junction plakoglobin	A0A3Q1M4X1 A0A3Q1MUL4 A2VDQ6 E1BQ11 F1ME22 Q0VCX4 Q2KJ51 Q8SPJ1	ADAM19 ADAM33 AMOT ANGPTL4 CDH11 CTNNB1 CTNND1 JUP
COPII-mediated vesicle transport	Alpha-1-antiproteinase Amphiregulin Ankyrin repeat domain 28 Bet1 golgi vesicular membrane trafficking protein Beta-soluble NSF attachment protein CD59 glycoprotein Casein kinase I isoform delta Cathepsin Z Coagulation factor V Coagulation factor VIII Dipeptidyl peptidase 1 Folate receptor-like domain-containing protein Gamma-soluble NSF attachment protein General vesicular transport factor p115 Glutamate receptor Golgi SNAP receptor complex member 2 Golgi reassembly stacking protein 1 Golgin A2 LMAN2 protein Lectin, mannose binding 1 like Lectin, mannose binding 1 Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit NSF attachment protein alpha Prolactin regulatory element-binding protein Protein SEC13 homolog Protein cornichon homolog 1 Protein phosphatase 6 regulatory subunit 1 Protein phosphatase 6 regulatory subunit 3 Protein transport protein SEC23 Protein transport protein Sec24A Protein transport protein Sec31A Protein transport protein sec16 Protein transport protein sec16 Ras-related protein Rab-1A SEC22A protein SEC23 interacting protein SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component SEC31 homolog B, COPII coat complex component Sec1 family domain containing 1 Serine/threonine-protein phosphatase Small COPII coat GTPase SAR1B Synaptobrevin homolog YKT6 Syntaxin-17 Syntaxin-5 TBC1 domain family member 20 TFG protein Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 1 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 4 Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Trafficking protein particle complex subunit Transforming growth factor alpha Transmembrane emp24 domain-containing protein 10 VIP36-like protein Vesicle-fusing ATPase Vesicle-trafficking protein SEC22b Vesicle-trafficking protein SEC22c small monomeric GTPase small monomeric GTPase	A0A3Q1LSE5 A0A3Q1LTM9 A0A3Q1LUP7 A0A3Q1M072 A0A3Q1M4U3 A0A3Q1M5V0 A0A3Q1M762 A0A3Q1M7J4 A0A3Q1M7M6 A0A3Q1MFL2 A0A3Q1MJE3 A0A3Q1MMA1 A0A3Q1MRB3 A0A3Q1MSA1 A0A3Q1MWA3 A0A3Q1N147 A0A3Q1NDZ1 A4FUG1 A6H7F7 A6QNT8 A6QP36 A7Z051 E1BG76 E1BIU0 E1BJ99 E1BKW5 E1BL12 E1BLS3 E1BMP2 E1BN43 E1BPR4 F1MEV4 F1MSD6 F1MTG7 F1MV07 F1MVW5 F1N0I3 F1N455 F1N6K7 F6Q334 G0T3G6 G3N214 G5E5W1 P05689 P34955 P35508 P41541 P81126 Q08DB5 Q17QI1 Q2HJD1 Q2KIC7 Q2T9Q1 Q2TBL9 Q2YDJ2 Q32L78 Q32PA1 Q3SX36 Q3T000 Q3T086 Q3T0F2 Q3T0T7 Q3ZCC9 Q5BIN6 Q5E971 Q5E9Y2	ANKRD28 AREG BET1 CD59 CNIH CNIH1 CSNK1D CTSC CTSZ F5 F8 FOLR3 GOLGA2 GORASP1 GOSR2 GRIA1 HCKID LMAN1 LMAN1L LMAN2 LMAN2L MCFD2 NAPA NAPB NAPG NSF PI PPP6C PPP6R1 PPP6R3 PREB RAB1A RAB1B SAPS3 SAR1B SCFD1 SEC13 SEC13L1 SEC16A SEC16B SEC22A SEC22B SEC22C SEC23A SEC23IP SEC24A SEC24B SEC24C SEC24D SEC31A SEC31B SERPINA1 SNAPB STX17 STX5 TBC1D20 TFG TGFA TMED10 TMP21 TRAPPC1 TRAPPC10 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9 USO1 VDP VIPL YKT6
EPH-ephrin mediated repulsion of cells	72 kDa type IV collagenase EPH receptor B6 Ephrin B2 Ephrin B3 Ephrin type-B receptor 3 Ephrin-B1 Gamma-secretase subunit APH-1 Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Matrix metalloproteinase-9 Nicastrin Presenilin-1 Presenilin-2 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase	A0A3Q1LNM1 A0A3Q1LXH4 A0A3Q1MBH7 A0A3Q1MDC6 A0A3Q1MQP9 A0JNB0 A1L570 A7MB57 E1BBD2 E1BIE4 E1BIM8 F1MII5 F1MKH8 F1ML02 F1N0M5 F1N261 F1N3R6 F1N5D4 P52176 Q5G235 Q9XT96 Q9XT97	APH1A APH1B EFNB1 EFNB2 EFNB3 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 FYN LYN MMP2 MMP9 NCSTN PEN2 PSEN1 PSEN2 PSENEN SRC VAV2 VAV3 YES1

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