GlyCosmos Portal

Bos taurus (domestic cattle)

Summary

Taxonomy ID: 9913
PubChem Taxonomy: 9913

Genes (2220) Glycans (1011) Glycoproteins (1219) Lectins (76) Pathways (548)

Displaying entries **1 - 25** of **548** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	GlyTouCan ID
Vasopressin regulates renal water homeostasis via Aquaporins	Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Arginine vasopressin G protein subunit beta 3 G protein subunit gamma 13 GNB4 protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Myosin VB Protein kinase cAMP-dependent type I regulatory subunit beta RAB11 family interacting protein 2 Ras-related protein Rab-11A Vasopressin V2 receptor cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase	A0A3Q1LXY0 A0A3Q1MCI6 A0A3Q1NGS8 A0A3S5ZPL0 A0A452DJE2 A4IFL6 A5PKD6 E1B8Q3 F1MMQ6 F1MYW8 F2Z4D5 G3X6N7 O77750 P00514 P00515 P00517 P02698 P11017 P30671 P47865 P48044 P50154 P62871 P63212 P63214 P63217 P79099 Q08DE6 Q28024 Q3SZ98 Q5E9F0	AQP1 AQP2 AQP3 AQP4 AVP AVPR2 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 MYO5B PRKACA PRKACB PRKAR1A PRKAR1B PRKAR2A RAB11A RAB11FIP2
Regulation of KIT signaling	E3 ubiquitin-protein ligase CBL Growth factor receptor-bound protein 2 Kit ligand Mast/stem cell growth factor receptor SH2B adaptor protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A3Q1LN00 A0A3Q1M739 A0A452DHX3 A0JNB0 A7MB57 E1BIM8 F1MRH8 F1N261 F1N7C3 Q28132 Q3T0F9 Q3ZCM0	CBL FYN GRB2 KIT KITLG LCK LYN PTPN6 SCF SH2B2 SOS1 SRC YES1
Acyl chain remodelling of PG	Cytosolic phospholipase A2 LPCAT4 protein LPGAT1 protein Lysophosphatidylcholine acyltransferase 1 PLA2G12A protein Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Secretory phospholipase A2 receptor cardiolipin synthase (CMP-forming) phospholipase A2	A0A3Q1MNU5 A0JNE8 A4IFJ5 A4IFP8 A5D7L0 A5PJS7 E1BEM2 E1BGU4 F1MG30 F1MNU5 F1MSG5 F1MTK4 P00593 P49259 Q56JZ2	CPLA2 CRLS1 LOC613966 LPCAT1 LPCAT4 LPGAT1 PLA2G12A PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G3 PLA2G4 PLA2G4A PLA2G4D PLA2G4F PLA2R1
Scavenging by Class B Receptors	Apolipoprotein A-I Apolipoprotein B Platelet glycoprotein 4 Scavenger receptor class B member 1	E1BNR0 O18824 P15497 P26201	APOA1 APOB CD36 PAS4 SCARB1
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Acetylcholine receptor subunit alpha Cholinergic receptor nicotinic alpha 6 subunit Cholinergic receptor nicotinic alpha 9 subunit Cholinergic receptor nicotinic beta 2 subunit Cholinergic receptor nicotinic beta 3 subunit Neuronal acetylcholine receptor subunit alpha-2 Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit alpha-5 Neuronal acetylcholine receptor subunit alpha-7 Neuronal acetylcholine receptor subunit beta-4	A0A3Q1MJN8 A6QPI7 E1BHK0 F1MC93 F1MDD1 F1MF30 F1MQ06 F1MYI7 F1N4T3 P02709 Q8SPU7	CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA6 CHRNA7 CHRNA9 CHRNB2 CHRNB3 CHRNB4
MyD88-independent TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 NAD(+) hydrolase SARM1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	A6QNL0 C4T7Z1 E1BIR9 Q2LGB7 Q6WCD5	CD14 LY96 MD-2 SARM1 TICAM2 TLR4 TRAM
Events associated with phagocytolytic activity of PMN cells	Lactoperoxidase MPO protein	A6QPT4 P80025	LPO MPO
RHOA GTPase cycle	A-kinase anchoring protein 13 ABCD3 protein Actin, alpha cardiac muscle 1 Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Aladin WD repeat nucleoporin Anillin, actin binding protein ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 B-cell receptor-associated protein BCR activator of RhoGEF and GTPase Caveolae associated protein 1 Caveolin-1 Coiled-coil domain-containing protein 115 Complement component 1 Q subcomponent-binding protein, mitochondrial DDRGK domain-containing protein 1 DEP domain containing 1B Dedicator of cytokinesis 2 Delta(14)-sterol reductase LBR Diaphanous related formin 1 Diaphanous related formin 3 Dishevelled associated activator of morphosis 1 ER membrane protein complex subunit 3 Endoplasmic reticulum protein 27 FAS-associated factor 2 FERM, ARHGEF and pleckstrin domain-containing protein 1 Family with sequence similarity 13 member A Flotillin-1 Flotillin-2 Formin like 3 GMIP protein IQ motif containing GTPase activating protein 1 IQGAP3 protein Junction plakoglobin Kinectin 1 Lectin, mannose binding 1 MCF.2 cell line derived transforming sequence like MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule Myosin IXB Neuroepithelial cell transforming 1 Neuronal guanine nucleotide exchange factor Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 Phospholipase Pleckstrin homology and RhoGEF domain containing G3 Pleckstrin homology and RhoGEF domain containing G5 Pleckstrin homology and RhoGEF domain containing G6 Progesterone receptor membrane component 2 Proto-oncogene vav Protocadherin 7 Rac GTPase activating protein 1 Ras protein specific guanine nucleotide releasing factor 2 Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 11A Rho GTPase activating protein 18 Rho GTPase activating protein 19 Rho GTPase activating protein 1 Rho GTPase activating protein 20 Rho GTPase activating protein 22 Rho GTPase activating protein 23 Rho GTPase activating protein 24 Rho GTPase activating protein 28 Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 42 Rho GTPase activating protein 44 Rho GTPase activating protein 45 Rho GTPase activating protein 4 Rho GTPase activating protein 5 Rho GTPase activating protein 6 Rho GTPase activating protein 8 Rho GTPase activating protein 9 Rho GTPase-activating protein 10 Rho GTPase-activating protein 26 Rho GTPase-activating protein 29 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 7 Rho-associated protein kinase 2 Rho-associated protein kinase Rho/Rac guanine nucleotide exchange factor 18 Rhophilin-2 Rhotekin SLIT-ROBO Rho GTPase activating protein 1 STOM protein Sec1 family domain containing 1 Serine/threonine-protein kinase N1 StAR related lipid transfer domain containing 13 StAR related lipid transfer domain containing 8 Starch binding domain 1 Synaptobrevin homolog YKT6 Synaptosomal-associated protein Syntaxin-5 T-cell activation GTPase activating protein TMEM87A protein Testis expressed 2 Tight junction protein 2 Transferrin receptor protein 1 Transforming protein RhoA V-type proton ATPase subunit S1 Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Vesicle-associated membrane protein-associated protein B heme oxygenase (biliverdin-producing) non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase protein kinase C protein kinase C	A0A3Q1LFQ5 A0A3Q1LGT5 A0A3Q1LHF1 A0A3Q1LKT3 A0A3Q1LM61 A0A3Q1LNB6 A0A3Q1LNE2 A0A3Q1LQ45 A0A3Q1LUD9 A0A3Q1LUW4 A0A3Q1LVS2 A0A3Q1LWV5 A0A3Q1LWX5 A0A3Q1LX25 A0A3Q1M2Q1 A0A3Q1M4A0 A0A3Q1M4M7 A0A3Q1M851 A0A3Q1M8D9 A0A3Q1MA88 A0A3Q1MAP3 A0A3Q1MD11 A0A3Q1MEH9 A0A3Q1MFP5 A0A3Q1MN47 A0A3Q1MPX1 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MSA1 A0A3Q1MT43 A0A3Q1MW77 A0A3Q1N5A2 A0A3Q1N6F4 A0A3Q1N6J8 A0A452DIS6 A0A452DJ82 A1A4I4 A2VDZ9 A4FUC9 A4FV18 A4FV22 A6H7H0 A6QLR4 A6QNS3 A6QQV8 A7YY57 A7Z038 A8E4P3 E1B718 E1B801 E1B9G8 E1BAJ4 E1BBA0 E1BBD2 E1BCC1 E1BCK4 E1BDL7 E1BDY4 E1BG76 E1BH05 E1BH51 E1BHQ9 E1BI70 E1BIG6 E1BIM3 E1BJP2 E1BLB3 E1BM23 E1BMN2 E1BNE7 E1BNR7 E1BNV7 E1BP14 E1BQ24 F1MBM9 F1MBT6 F1MC48 F1MCL8 F1MCN4 F1MEK6 F1MF50 F1MFA5 F1MFC6 F1MFK1 F1MFS4 F1MGB9 F1MHI2 F1MIZ6 F1MJA6 F1MJH8 F1MK36 F1MLS2 F1MM72 F1MPJ6 F1MS34 F1MTN6 F1MTY9 F1MWY5 F1MYQ4 F1N1Q7 F1N2G5 F1N6V1 F1N7Q8 F6QCG0 F6QJJ8 F6RWK1 G3N2T3 G3X696 G5E6T2 P23726 P23727 P40682 P61585 P79132 Q08DA6 Q08DB1 Q08DB5 Q08DN7 Q08DN8 Q08DP6 Q2HJD0 Q2T9M8 Q3SZB5 Q3T000 Q3T0B6 Q3ZC07 Q3ZCB8 Q5E9F1 Q8SPJ1	AAAS ABCD3 ABR ACBD5 ACTC ACTC1 AKAP13 ANLN ARAP1 ARAP2 ARAP3 ARHA ARHGAP1 ARHGAP10 ARHGAP11A ARHGAP18 ARHGAP19 ARHGAP20 ARHGAP22 ARHGAP23 ARHGAP24 ARHGAP26 ARHGAP28 ARHGAP29 ARHGAP30 ARHGAP31 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP42 ARHGAP44 ARHGAP45 ARHGAP5 ARHGAP6 ARHGAP8 ARHGAP9 ARHGDIA ARHGDIB ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF25 ARHGEF28 ARHGEF3 ARHGEF5 ARHGEF7 ATP6AP1 ATP6IP1 ATP6S1 BCAP31 BCR C1QBP CAV1 CAVIN1 CCDC115 DAAM1 DDRGK1 DEPDC1B DIAPH1 DIAPH3 DLC1 DOCK2 EMC3 ERP27 FAF2 FAM13A FARP1 FLOT1 FLOT2 FMNL3 GMIP HMOX2 IQGAP1 IQGAP3 JUP KTN1 LBR LMAN1 MCAM MCF2L MYO9B NET1 NGEF OPHN1 PCDH7 PGRMC2 PIK3R1 PIK3R2 PKN PKN1 PKN2 PKN3 PLD1 PLEKHG3 PLEKHG5 PLEKHG6 PREX1 PREX2 PRK1 PRKCL1 RACGAP1 RASGRF2 RHO12 RHOA RHPN2 ROCK1 ROCK2 RTKN SCFD1 SLK SNAP23 SRGAP1 STARD13 STARD8 STBD1 STOM STX5 TAGAP TEX2 TFRC TJP2 TMEM111 TMEM87A TRIO UBXD8 VANGL1 VAPB VAV1 VAV2 VAV3 YKT6
Antigen processing: Ubiquitination & Proteasome degradation	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Aminopeptidase Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 13 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 Ankyrin repeat and SOCS box containing 10 Ankyrin repeat and SOCS box containing 12 Ankyrin repeat and SOCS box containing 13 Ankyrin repeat and SOCS box containing 14 Ankyrin repeat and SOCS box containing 1 Ankyrin repeat and SOCS box containing 4 Ankyrin repeat and SOCS box containing 6 Ankyrin repeat and SOCS box containing 7 Ankyrin repeat and SOCS box containing 9 Ankyrin repeat and SOCS box protein 11 Ankyrin repeat and SOCS box protein 15 Ankyrin repeat and SOCS box protein 17 Ankyrin repeat and SOCS box protein 5 Ankyrin repeat and SOCS box protein 8 BTB domain containing 1 BTB domain containing 6 BTB/POZ domain-containing protein KCTD7 Bleomycin hydrolase CUL2 protein Cell division cycle 16 Cell division cycle 20 Cell division cycle 34, ubiqiutin conjugating enzyme Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cullin 1 Cullin 3 Cullin 7 Cullin-5 DDB1 and CUL4 associated factor 1 DET1 partner of COP1 E3 ubiquitin ligase E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E3 UFM1-protein ligase 1 E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase E3D E3 ubiquitin-protein ligase HACE1 E3 ubiquitin-protein ligase Hakai E3 ubiquitin-protein ligase NRDP1 E3 ubiquitin-protein ligase RNF114 E3 ubiquitin-protein ligase RNF126 E3 ubiquitin-protein ligase RNF138 E3 ubiquitin-protein ligase RNF182 E3 ubiquitin-protein ligase RNF34 E3 ubiquitin-protein ligase SH3RF1 E3 ubiquitin-protein ligase TRIM21 E3 ubiquitin-protein ligase TRIM71 E3 ubiquitin-protein ligase TRIM9 E3 ubiquitin-protein ligase TRIP12 E3 ubiquitin-protein ligase ZNRF1 E3 ubiquitin-protein ligase listerin E3 ubiquitin-protein ligase parkin E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Elongin-C F-box and WD repeat domain containing 11 F-box and WD repeat domain containing 4 F-box and WD repeat domain containing 5 F-box and WD repeat domain containing 8 F-box and WD repeat domain containing 9 F-box and leucine rich repeat protein 13 F-box and leucine rich repeat protein 14 F-box and leucine rich repeat protein 16 F-box and leucine rich repeat protein 18 F-box and leucine rich repeat protein 19 F-box and leucine rich repeat protein 21 F-box and leucine rich repeat protein 4 F-box and leucine rich repeat protein 7 F-box domain-containing protein F-box only protein 27-like F-box only protein 2 F-box only protein 32 F-box only protein 4 F-box only protein 6 F-box only protein 9 F-box protein 10 F-box protein 11 F-box protein 15 F-box protein 21 F-box protein 22 F-box protein 30 F-box protein 31 F-box protein 40 F-box protein 41 F-box protein 7 F-box/LRR-repeat protein 12 F-box/LRR-repeat protein 15 F-box/LRR-repeat protein 20 F-box/LRR-repeat protein 5 F-box/WD repeat-containing protein 2 F-box/WD repeat-containing protein 7 FBXO44 protein Fizzy/cell division cycle 20 related 1 (Drosophila) Gigaxonin Glomulin, FKBP associated protein HECT and RLD domain containing E3 ubiquitin protein ligase 3 HECT and RLD domain containing E3 ubiquitin protein ligase 4 HECT and RLD domain containing E3 ubiquitin protein ligase 5 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 HECT domain E3 ubiquitin protein ligase 3 HECT-type E3 ubiquitin transferase HECT-type E3 ubiquitin transferase HECT-type E3 ubiquitin transferase HECT-type E3 ubiquitin transferase HECT-type E3 ubiquitin transferase HECT-type E3 ubiquitin transferase HECT-type E3 ubiquitin transferase HECT-type E3 ubiquitin transferase KBTBD10 protein KCTD6 protein Kelch like family member 11 Kelch like family member 2 Kelch like family member 42 Kelch like family member 5 Kelch like family member 9 Kelch repeat and BTB domain containing 13 Kelch repeat and BTB domain containing 6 Kelch repeat and BTB domain containing 7 Kelch repeat and BTB domain containing 8 Kelch-like ECH-associated protein 1 Kelch-like protein 13 Kelch-like protein 20 Kelch-like protein 21 Kelch-like protein 22 Kelch-like protein 3 LIM domain 7 LNX1 protein LON peptidase N-terminal domain and ring finger 1 Leucine rich repeat and sterile alpha motif containing 1 Leucine-rich repeat-containing protein 41 Mex-3 RNA binding family member C NEDD8-activating enzyme E1 catalytic subunit NEDD8-conjugating enzyme UBE2F NEDD8-conjugating enzyme Ubc12 PPIL5 protein Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta Proteasome subunit beta RB binding protein 6, ubiquitin ligase RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RCHY1 protein RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Ring finger protein 130 Ring finger protein 213 Ring finger protein 220 Ring finger protein 25 Ring finger protein 4 Ring finger protein 6 S-phase kinase-associated protein 1 SKP2 protein SplA/ryanodine receptor domain and SOCS box containing 1 SplA/ryanodine receptor domain and SOCS box containing 2 SplA/ryanodine receptor domain and SOCS box containing 4 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) Tripartite motif containing 11 Tripartite motif containing 37 Tripartite motif containing 39 Tripartite motif containing 41 Tripartite motif containing 4 Tripartite motif containing 50 Tripartite motif containing 69 Tripeptidyl-peptidase 2 UBA domain containing 1 Ubiquitin conjugating enzyme E2 A Ubiquitin conjugating enzyme E2 D3 Ubiquitin conjugating enzyme E2 E2 Ubiquitin conjugating enzyme E2 L6 Ubiquitin conjugating enzyme E2 O Ubiquitin conjugating enzyme E2 Q1 Ubiquitin conjugating enzyme E2 R2 Ubiquitin conjugating enzyme E2 U Ubiquitin conjugation factor E4 A Ubiquitin like modifier activating enzyme 6 Ubiquitin like modifier activating enzyme 7 Ubiquitin protein ligase E3 component n-recognin 4 Ubiquitin protein ligase E3B Ubiquitin-conjugating enzyme E2 B Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 E3 Ubiquitin-conjugating enzyme E2 G2 Ubiquitin-conjugating enzyme E2 H Ubiquitin-conjugating enzyme E2 J2 Ubiquitin-conjugating enzyme E2 K Ubiquitin-conjugating enzyme E2 L3 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 Q2 Ubiquitin-conjugating enzyme E2 S Ubiquitin-conjugating enzyme E2 W Ubiquitin-conjugating enzyme E2 Z Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-like modifier-activating enzyme 1 Ubiquitin-like modifier-activating enzyme 5 Ubiquitin-like modifier-activating enzyme ATG7 Ubiquitin-protein ligase E3A Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Unk like zinc finger WD repeat and SOCS box-containing protein 1 cullin-RING-type E3 NEDD8 transferase	A0A3Q1LFJ4 A0A3Q1LJ39 A0A3Q1LK96 A0A3Q1LNU6 A0A3Q1LPN8 A0A3Q1LQM8 A0A3Q1LRM2 A0A3Q1LV49 A0A3Q1LV60 A0A3Q1LVT3 A0A3Q1LWA6 A0A3Q1LX18 A0A3Q1LXA9 A0A3Q1M118 A0A3Q1M231 A0A3Q1M5N0 A0A3Q1M674 A0A3Q1M680 A0A3Q1M7U1 A0A3Q1M862 A0A3Q1M996 A0A3Q1MAR8 A0A3Q1MCW5 A0A3Q1MD47 A0A3Q1MDP9 A0A3Q1MHT7 A0A3Q1MJI4 A0A3Q1MJT8 A0A3Q1MLB6 A0A3Q1MLH2 A0A3Q1MLW5 A0A3Q1MMU6 A0A3Q1MN48 A0A3Q1MNS5 A0A3Q1MNZ4 A0A3Q1MPJ6 A0A3Q1MXH0 A0A3Q1MY63 A0A3Q1N1L9 A0A3Q1N1X1 A0A3Q1N1Y8 A0A3S5ZPN9 A0A452DHW1 A0A452DI01 A0A452DIC0 A0A452DII5 A0A452DJ29 A0A452DJ71 A0A452DJQ7 A1A4I9 A1A4R8 A1L5A6 A2VDP7 A2VDU5 A2VE78 A3KMV5 A3KN22 A4FV78 A4IFA2 A4IFB4 A4IFE2 A4IFN7 A5D7F8 A5PJX0 A5PKG6 A5PKK2 A5PKM1 A6H795 A6QLE0 A6QLT0 A6QPV4 A6QQD1 A6QQY2 A6QR43 A7MAZ3 A7MB09 A7MBA2 A7MBG4 A7MBH8 A7Z061 E1B782 E1B7D3 E1B7G3 E1B7Q7 E1B8R6 E1B945 E1B964 E1B9Q3 E1B9S2 E1BA27 E1BAB6 E1BAV2 E1BAY5 E1BB00 E1BBI7 E1BBN5 E1BBY2 E1BBZ9 E1BCM1 E1BCU1 E1BCW1 E1BCZ2 E1BDV4 E1BEH6 E1BF94 E1BGD4 E1BGE6 E1BH71 E1BHT5 E1BHZ2 E1BID7 E1BIE5 E1BIN5 E1BIP5 E1BIW0 E1BJ12 E1BK00 E1BK11 E1BK68 E1BKE5 E1BL26 E1BL29 E1BLD1 E1BM34 E1BNQ6 E1BNY9 E1BP91 E1BPM5 F1MBI1 F1MBM6 F1MBP6 F1MBQ2 F1MD71 F1MDA7 F1ME38 F1MEB7 F1MEK2 F1MEX6 F1MF12 F1MFH5 F1MFL6 F1MGQ5 F1MJ10 F1MJS5 F1MLS5 F1MLV1 F1MM41 F1MNN4 F1MR99 F1MRW5 F1MSC9 F1MSN0 F1MTH1 F1MTS8 F1MWE0 F1MWS4 F1MWW0 F1MXE4 F1MXI0 F1MXY6 F1MYD0 F1MYH8 F1MYL0 F1MZA8 F1N019 F1N0W7 F1N1C5 F1N1M5 F1N1X8 F1N3I3 F1N465 F1N495 F1N4D3 F1N5G3 F1N5X8 F1N645 F1N6G5 F1N703 F1N7A0 F1N7C1 F2Z4G9 F6PQR5 F6Q4D3 F6R269 F6RV66 F6RVN5 G3MY23 G3N1I7 G3N1P6 G3N2X5 G3N2Y1 G5E589 G8JKY1 H7BWV6 M5FKI3 P0CG53 P0CH28 P33672 P56701 P61085 P62194 P62992 P63048 Q08DE9 Q08DK3 Q08DS1 Q08E43 Q0II22 Q0P5F4 Q0P5K3 Q0V7P2 Q0VCP5 Q17QG5 Q17QK6 Q17QP9 Q17QS6 Q1JPC8 Q1JQA1 Q1RMK0 Q1RML1 Q1RMW1 Q1RMX2 Q29RQ5 Q2KHT6 Q2KI42 Q2KI91 Q2KII4 Q2KJ25 Q2KJ46 Q2NKV2 Q2T9X7 Q2TA03 Q2TA10 Q2YDE4 Q32KL2 Q32KY8 Q32L05 Q32L27 Q32LN1 Q32LN5 Q32P99 Q32PA5 Q32PG0 Q32PG9 Q3MHN0 Q3MHP1 Q3SX24 Q3SZ32 Q3SZT7 Q3T030 Q3T0J1 Q3T0X5 Q3T0Y5 Q3T108 Q3ZBD0 Q3ZBG0 Q3ZBT2 Q3ZCF3 Q3ZCF6 Q3ZCK9 Q4U5R4 Q58D00 Q58DG6 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9J6 Q5E9K0 Q7YRV4 Q8HXA6 Q9BEG9	ADRM1 ANAPC1 ANAPC10 ANAPC11 ANAPC13 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANAPC8 AREL1 ARIH2 ASB1 ASB10 ASB11 ASB12 ASB13 ASB14 ASB15 ASB17 ASB4 ASB5 ASB6 ASB7 ASB8 ASB9 ATG7 BLMH BTBD1 BTBD6 C20orf18 CBLL1 CDC16 CDC20 CDC23 CDC26 CDC27 CDC34 CUL1 CUL2 CUL3 CUL5 CUL7 DCAF1 DET1 DTX3L DZIP3 ELOC FBS2 FBW7 FBX6 FBXL12 FBXL13 FBXL14 FBXL15 FBXL16 FBXL18 FBXL19 FBXL20 FBXL21 FBXL4 FBXL5 FBXL7 FBXO10 FBXO11 FBXO15 FBXO2 FBXO21 FBXO22 FBXO30 FBXO31 FBXO32 FBXO4 FBXO40 FBXO41 FBXO44 FBXO6 FBXO7 FBXO9 FBXW11 FBXW2 FBXW4 FBXW5 FBXW7 FBXW8 FBXW9 FZR1 GAN GLMN H10BH HACE1 HECTD1 HECTD2 HECTD3 HECW2 HERC2 HERC3 HERC4 HERC5 HERC6 HIP2 HUWE1 ITCH KBTBD10 KBTBD13 KBTBD6 KBTBD7 KBTBD8 KCTD6 KCTD7 KEAP1 KLHL11 KLHL13 KLHL2 KLHL20 KLHL21 KLHL22 KLHL3 KLHL42 KLHL5 KLHL9 LMO7 LNX1 LOC528919 LOC789309 LONRF1 LRRC41 LRSAM1 LTN1 MEX3C MGRN1 MIB2 MKRN1 MYLIP NEDD4 NEDD4L NPEPPS PJA1 PJA2 POSH POSH1 PPIL5 PRKN PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RBBP6 RBCK1 RCHY1 RLIM RNF111 RNF114 RNF115 RNF123 RNF126 RNF130 RNF138 RNF14 RNF144B RNF182 RNF19A RNF19B RNF213 RNF217 RNF25 RNF34 RNF4 RNF41 RNF6 RNF7 RPS27A SH3RF1 SIAH1 SIAH2 SKP1 SKP1A SKP2 SMURF1 SMURF2 SOCS1 SOCS3 SPSB1 SPSB2 SPSB4 STUB1 SUG1 TCEB1 TCEB2 TPP2 TRAP2 TRIM11 TRIM21 TRIM32 TRIM36 TRIM37 TRIM39 TRIM4 TRIM41 TRIM50 TRIM63 TRIM69 TRIM71 TRIM9 TRIP12 UBA1 UBA3 UBA5 UBA52 UBA6 UBA7 UBA80 UBAC1 UBB UBC UBC12 UBC4 UBC7 UBCEP1 UBCEP2 UBCH10 UBCH4 UBCH5B UBE1 UBE2A UBE2B UBE2C UBE2CBP UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2F UBE2G1 UBE2G2 UBE2H UBE2J1 UBE2J2 UBE2K UBE2L3 UBE2L6 UBE2M UBE2N UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2S UBE2U UBE2V2 UBE2W UBE2Z UBE3A UBE3B UBE3C UBE3D UBE4A UBR1 UBR2 UBR4 UFL1 UNKL WSB1 WWP1 ZNF313 ZNRF1 ZNRF2
Transport of organic anions	Arginine vasopressin Solute carrier family 16 member 2 Solute carrier organic anion transporter family member 3A1 Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member	A0A3Q1LXY0 A0A3S5ZP51 A2VDW7 E1BC23 E1BPV8 F1MM56 F1MQ45 F1MYV0 F1N3T5 Q8HYW2	AVP OATP3A1 OATPD SLC16A2 SLC21A11 SLCO1A2 SLCO1B3 SLCO1C1 SLCO2A1 SLCO2B1 SLCO3A1 SLCO4A1 SLCO4C1
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma B cell linker B-cell antigen receptor complex-associated protein alpha chain B-cell receptor CD22 CD19 molecule CD79b molecule Cytoplasmic protein Dual adaptor of phosphotyrosine and 3-phosphoinositides Growth factor receptor-bound protein 2 Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase adaptor protein 1 Proto-oncogene vav SH3 domain containing kinase binding protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Short transient receptor potential channel 1 Stromal interaction molecule 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1LKV0 A0A3Q1M535 A0A3Q1M739 A0A3Q1M839 A0A3Q1MFU0 A0A3Q1MHG9 A0A3Q1MMD9 A0A3Q1N7P8 A0A3Q1NI55 A0A3Q1NIZ6 A0A3S5ZPA3 E1BE66 E1BKE7 F1MMQ7 F1MX21 F1N586 F1N7C3 G5E513 P23727 P40293 Q08DN7 Q08DV4 Q1LZB2 Q3T0F9 Q3ZC95	BLNK BTK CD19 CD22 CD79A CD79B DAPP1 GRB2 IGA ITPR1 ITPR2 ITPR3 MB-1 NCK1 PIK3AP1 PIK3CD PIK3R1 PLCG2 PTPN6 SH3KBP1 SOS1 STIM1 SYK TRPC1 VAV1
RAF/MAP kinase cascade	Alpha-actinin-2 Amphiregulin Angiopoietin-1 receptor Angiopoietin-1 Artemin Astrocytic phosphoprotein PEA-15 Betacellulin Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Colony stimulating factor 2 receptor subunit beta Cytokine receptor common subunit gamma Discs large MAGUK scaffold protein 3 Discs large MAGUK scaffold protein 4 Disks large homolog 1 EF-hand domain-containing protein EF-hand domain-containing protein Epiregulin Epithelial mitogen FLT3LG protein FRS3 protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Focal adhesion kinase 1 GDNF family receptor alpha 4 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GFRA3 protein GTPase NRas Glial cell derived neurotrophic factor Granulocyte-macrophage colony-stimulating factor Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 3 receptor subunit alpha Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 Interleukin-3 Interleukin-5 Kit ligand Klotho beta Klotho Linker for activation of T cells Mast/stem cell growth factor receptor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Neuregulin 2 Neuregulin 3 Neurofilament light polypeptide Neurturin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase receptor Ret RAS guanyl releasing protein 3 RAS guanyl releasing protein 4 RAS guanyl-releasing protein 1 Ral guanine nucleotide dissociation stimulator like 1 Ral guanine nucleotide dissociation stimulator like 3 Ral guanine nucleotide dissociation stimulator-like 2 Ral guanine nucleotide dissociation stimulator Ran-binding protein 9 Rap guanine nucleotide exchange factor 2 Ras protein specific guanine nucleotide releasing factor 1 Ras protein specific guanine nucleotide releasing factor 2 RasGEF domain family member 1A Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor-type tyrosine-protein phosphatase alpha SHC adaptor protein 2 SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Spectrin alpha, erythrocytic 1 Spectrin alpha, non-erythrocytic 1 Spectrin beta chain Spectrin beta chain Spectrin beta chain Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase calcium/calmodulin-dependent protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase small monomeric GTPase	A0A3Q1LI10 A0A3Q1LK34 A0A3Q1LNC8 A0A3Q1LRU7 A0A3Q1LSU3 A0A3Q1LUE0 A0A3Q1M0Y1 A0A3Q1M3Q3 A0A3Q1M6Z6 A0A3Q1M7J4 A0A3Q1MBH0 A0A3Q1MD11 A0A3Q1ME99 A0A3Q1MFJ1 A0A3Q1MHB0 A0A3Q1MKB4 A0A3Q1MKC7 A0A3Q1MPB6 A0A3Q1MPT9 A0A3Q1MR28 A0A3Q1N010 A0A3Q1N3Z8 A0A3Q1N508 A0A3Q1N8H3 A0A3Q1NAC7 A0A3Q1NAV6 A0A452DHX3 A0A452DJB1 A0JNB0 A0MTF4 A2VE24 A2VE27 A2VE30 A4IFA9 A5D7R9 A6H792 A6QR62 B1H0W5 D8KXU9 E1B7I9 E1B8P9 E1BAI2 E1BBE2 E1BCP6 E1BD76 E1BDM2 E1BEL4 E1BFP8 E1BG59 E1BGY3 E1BHC1 E1BIN8 E1BJC7 E1BJU2 E1BKU1 E1BLT3 E1BM01 E1BMN5 E1BMX0 E1BP37 F1MCQ7 F1MEV4 F1MH16 F1MHC6 F1MJE0 F1MKE9 F1MLH6 F1MM66 F1MMQ8 F1MN51 F1MP52 F1MPD0 F1MRU0 F1MS00 F1MS28 F1MSG6 F1MXH7 F1MYE0 F1MYM3 F1MZ60 F1MZD6 F1N0D6 F1N4S9 F1N5N3 F1N6G8 F1N7C3 F2Z4J0 F6S0Q2 G3MXR4 G3MZM3 G3N104 G3XGD3 O18920 P02548 P03968 P03969 P05016 P11052 P23726 P23727 P32871 P46196 P49875 P52173 Q06807 Q0IIE2 Q0VCY4 Q0VCY8 Q28132 Q2HJF7 Q2KJ15 Q3MHJ9 Q3T0F9 Q3ZC55 Q95118 Z4YHD9	ACTN2 AFGF ANG1 ANGPT1 AREG ARTN BTC CALM CAMK2A CAMK2B CAMK2D CSF2 CSF2RB DLG1 DLG3 DLG4 EGFR EPGN ERBB2 ERBB3 ERBB4 EREG ERK2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF8A FGF9 FGFA FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FRS3 FYN Fgf4 GDNF GFRA1 GFRA2 GFRA3 GFRA4 GRB2 HBEGF HBGF-1 HGF IL-2 IL2 IL2RA IL2RG IL3 IL3RA IL5 IL5RA IRS1 IRS2 JAK1 JAK2 JAK3 KIT KITLG KL KLB KRAS LAT MAPK1 MAPK3 MET NEFL NRAPGEP NRAS NRG1 NRG2 NRG3 NRTN PDGFA PDGFB PDGFRA PDGFRB PDZGEF1 PEA15 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKM1 PTK2 PTPRA RALGDS RANBP9 RAPGEF2 RASGEF1A RASGRF1 RASGRF2 RASGRP1 RASGRP3 RASGRP4 RET RGL1 RGL2 RGL3 SCF SHC1 SHC2 SHC3 SOS1 SPTA1 SPTAN1 SPTB SPTBN2 SPTBN4 TEK TGFA TIE-2 TIE2
Stabilization of p53	Cellular tumor antigen p53 Checkpoint kinase 2 E3 ubiquitin-protein ligase Mdm2 Serine-protein kinase ATM	E1BEI6 F1MYE6 F6R5E4 P67939	ATM CHEK2 MDM2 TP53
TP53 Regulates Transcription of Death Receptors and Ligands	Insulin-like growth factor-binding protein 3 receptor Insulin-like growth factor-binding protein 3	P20959 Q1JQE1	IGFBP3 TMEM219
PI-3K cascade:FGFR2	Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2-associated-binding protein 1 Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type	A0A3Q1LRU7 A0A3Q1M3Q3 A0A3Q1NAV6 A0MTF4 A6QLU3 D8KXU9 E1B7I9 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MHC6 F1N339 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969 P23727 P32871 Q3T0F9	AFGF FGF1 FGF10 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF9 FGFA FGFR2 FRS2 Fgf4 GAB1 GRB2 HBGF-1 PIK3CA PIK3R1 PTPN11
Activated NTRK3 signals through PI3K	Neurotrophin-3 Tyrosine-protein kinase receptor Tyrosine-protein kinase	E1BIM8 G3N3T6 Q08DT3	NTF3 NTRK3 SRC
Elevation of cytosolic Ca2+ levels	Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor P2X purinoceptor 4 P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Short transient receptor potential channel 6 Transient receptor potential cation channel subfamily C member 3 Transient receptor potential cation channel subfamily C member 7	A0A3Q1LTG6 A0A3Q1M4W2 A0A3Q1N7P8 E1B742 E1BIH1 E1BIP1 E1BKE7 F1MUF3 F1MVZ6 F1MX21 F1N7A9 Q5E9U1 Q9MYW0	ITPR1 ITPR2 ITPR3 P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 TRP6 TRPC3 TRPC6 TRPC7
Interleukin receptor SHC signaling	Colony stimulating factor 2 receptor subunit beta Cytokine receptor common subunit gamma GRB2 associated binding protein 2 Granulocyte-macrophage colony-stimulating factor Growth factor receptor-bound protein 2 Interleukin 3 receptor subunit alpha Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 Interleukin-3 Interleukin-5 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1LJT8 A0A3Q1LK34 A0A3Q1M739 A0A3Q1M864 A2VE30 E1BBJ7 E1BCP6 E1BE66 E1BEL4 F1MDQ5 F1MH16 F1MXH7 F1MYM3 F1N0D6 F1N7C3 P05016 P11052 P23726 P23727 P32871 P49875 P52173 Q0IIE2 Q3T0F9 Q95118	CSF2 CSF2RB GAB2 GRB2 IL-2 IL2 IL2RA IL2RG IL3 IL3RA IL5 IL5RA INPP5D INPPL1 JAK1 JAK2 JAK3 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PTPN6 SHC1 SOS1
Activation of G protein gated Potassium channels	ATP-sensitive inward rectifier potassium channel 12 G protein subunit beta 3 G protein subunit gamma 13 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 4 GNB4 protein Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Inward rectifier potassium channel 2 KCNJ10 protein KCNJ15 protein Potassium inwardly rectifying channel subfamily J member 16 Potassium inwardly rectifying channel subfamily J member 4	A0A3Q1M4V6 A0A3Q1NGS8 A0A3S5ZPL0 A2VDQ4 A4IFL6 A5PJL2 A5PKD6 E1B8Q3 E1BNE9 F1MF15 F1MIZ5 F1MUD1 F1MYR9 F1MYW8 O19182 P02698 P11017 P30671 P50154 P62871 P63212 P63214 P63217 Q0VD28 Q28024 Q3SZ98 Q4TZY1 Q5E9F0	GABBR1 GABBR2 GIRK1 GIRK4 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 IRK1 KCNJ10 KCNJ12 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6
Sphingolipid catabolism	Aldehyde dehydrogenase family 3 member A2 Aldehyde dehydrogenase family 3 member B1 Alkaline ceramidase Alkaline ceramidase Alkaline ceramidase Phospholipid phosphatase 1 Phospholipid phosphatase 2 Phospholipid phosphatase 3 Sphingosine-1-phosphate phosphatase 1 sphinganine-1-phosphate aldolase	A0A3Q1LJ52 A0A3Q1LM94 A0A3Q1MIK4 A0JNA1 A7MBH7 E1B8N2 F1MGH9 Q1JPA0 Q2HJ61 Q3SZE3	ACER1 ACER2 ACER3 ALDH3A2 ALDH3B1 PLPP1 PLPP2 PLPP3 PPAP2B PPAP2C SGPL1 SGPP1
Lysosphingolipid and LPA receptors	Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 5 Phospholipid phosphatase related 2 Phospholipid phosphatase related 3 Phospholipid phosphatase related 4 Phospholipid phosphatase related 5 Phospholipid phosphatase-related protein type 1 S1PR3 protein Sphingosine 1-phosphate receptor 1 Sphingosine-1-phosphate receptor 2 Sphingosine-1-phosphate receptor 5	A0A3Q1LQD3 A0A3Q1M4L7 A0A3Q1M9C6 A2VDV6 A6QR17 E1BJF3 E1BLD8 F1MJ26 F1MU59 F1MV28 F1MX11 Q3ZC80 Q5E9P3	EDG1 GPR92 LPAR1 LPAR2 LPAR3 LPAR5 PLPPR1 PLPPR2 PLPPR3 PLPPR4 PLPPR5 S1PR1 S1PR2 S1PR3 S1PR5
P2Y receptors	G protein-coupled receptor 17 LPAR4 protein Lysophosphatidic acid receptor 6 P2Y purinoceptor 14 P2Y purinoceptor 1 P2Y purinoceptor 2 P2Y purinoceptor 4 P2Y receptor family member 10 Purinergic receptor P2Y, G-protein coupled, 12 Purinergic receptor P2Y11 Pyrimidinergic receptor P2Y6	A2VEA2 A4IFV1 A6QL49 F1MDI7 F1MDW9 F1MTB2 F1MU50 G3X6Q0 P48042 Q0IIL0 Q3SX17	GPR17 LPAR4 LPAR6 P2RY1 P2RY10 P2RY11 P2RY12 P2RY14 P2RY2 P2RY4 P2RY5 P2RY6
Gluconeogenesis	Beta-enolase Enolase 4 Fructose-1,6-bisphosphatase 1 Fructose-1,6-bisphosphatase isozyme 2 Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase Glucose-6-phosphatase 3 Glucose-6-phosphatase catalytic subunit 1 Glucose-6-phosphatase Glucose-6-phosphate exchanger SLC37A2 Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase, testis-specific Glyceraldehyde-3-phosphate dehydrogenase Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Phosphoglycerate kinase 1 Phosphoglycerate mutase 1 Phosphoglycerate mutase Pyruvate carboxylase, mitochondrial Solute carrier family 37 member 1 Solute carrier family 37 member 4 Triosephosphate isomerase phosphoenolpyruvate carboxykinase (GTP) phosphopyruvate hydratase	A0A3Q1LIP1 A0A3Q1LMG1 A0A3Q1M1A8 A0A3Q1MDS5 A0A3S5ZPB0 A0A452DIX3 A6QR19 E1B9Q0 F1MDS3 F1MSR0 F1N2F2 F6RG16 G3MXL6 P10096 Q148G2 Q29RK2 Q29RU6 Q2KJE5 Q2KJJ9 Q3SZ62 Q3SZB7 Q3T0P6 Q3ZBD7 Q3ZC09	ALDOA ALDOB ALDOC ENO2 ENO3 ENO4 FBP1 FBP2 G6PC G6PC1 G6PC2 G6PC3 GAPD GAPDH GAPDHS GPI PC PCK1 PCK2 PGAM1 PGAM2 PGK1 SLC37A1 SLC37A2 SLC37A4 TPI1	G58161NS
HSP90 chaperone cycle for SHRs	Actin-related protein 10 Alpha-centractin Androgen receptor Cytoplasmic dynein 1 intermediate chain 1 DnaJ heat shock protein family (Hsp40) member A4 DnaJ homolog subfamily A member 1 DnaJ homolog subfamily A member 2 DnaJ homolog subfamily B member 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein heavy chain, cytosolic Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Dynein light intermediate chain Dynein light intermediate chain F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha Glucocorticoid receptor Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock-related 70 kDa protein 2 Mineralocorticoid receptor Progesterone receptor Prostaglandin E synthase 3 Stress-induced-phosphoprotein 1 peptidylprolyl isomerase peptidylprolyl isomerase	A0A3Q1M3Y3 A0A3Q1MUW5 A0A3Q1N5N2 A0A3Q1NEU9 A0A452DIU3 A4FUA8 A7E3Q2 E1BBI8 F1MBQ0 F1MN19 F1MU79 F1N2B6 F1N6Q0 F1N712 F2Z4F0 G3MXV0 P0CB32 P19120 P61285 Q0P5A1 Q148G7 Q27975 Q29RQ3 Q2HJ94 Q2KII9 Q32KS3 Q3MHR3 Q3MI00 Q3ZBD2 Q3ZBZ8 Q3ZCF0 Q5E954 Q5E997 Q76LV1 Q76LV2	ACTR10 ACTR1A AR ARP10 CAPZA1 CAPZA2 CAPZA3 DCTN1 DCTN2 DCTN3 DCTN4 DCTN5 DCTN6 DNAJA1 DNAJA2 DNAJA4 DNAJB1 DNCL1 DYNC1H1 DYNC1I1 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 FKBP4 FKBP5 HSC70 HSP70-1 HSP90A HSP90AA1 HSP90AB1 HSPA1A HSPA1L HSPA2 HSPA8 HSPC3 HSPCA HSPCB NR3C1 NR3C2 PGR PTGES3 STIP1
Physiological factors	Atrial natriuretic peptide receptor 2 C-type natriuretic peptide Carboxylic ester hydrolase Corin, serine peptidase Guanylate cyclase Natriuretic peptides A Neprilysin	A0A3Q1LLW8 A0A3Q1MQJ1 E1BN71 E1BPL8 P07501 P46197 P55206	CES1 CORIN MME NPPA NPPC NPR1 NPR2

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Acknowledgements