Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Species Pathogen Adherence Molecule Ligand Name Ligand Feature Target Source Glycan Sequence Binding PubMed ID
68-kDa proteins
N-Acetylneuraminic acid
Monosaccharides
Bronchial lavages of sheep with pneumonic pasteurelosis
NeuAc
Binding
PrsG (class III)
SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5)
Monosialoglycosphingolipids
Human kidney tissues
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
PapG (class I)
SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5)
Monosialoglycosphingolipids
Human kidney tissues
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
P-fimbriae
SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5)
Monosialoglycosphingolipids
Human kidney tissues
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
PapG (class II)
SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5)
Monosialoglycosphingolipids
Human kidney tissues
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
Neutrophil-activating proteins (150-kDa)
Sialyl Lewis a (SLea) (GSL)
Monosialoglycosphingolipids
Human bile bladder tumor
NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
Not Binding
SSL5
Sialyl Lewis x (SLex) antigen
Oligosaccharides
(broad range)
NeuAc(a2-3)Gal(b1-4)
Binding
SSL11
Sialyl Lewis x (SLex) antigen
Oligosaccharides
(broad range)
NeuAc(a2-3)Gal(b1-4)
Binding
SabA (sialic acid-binding adhesin)
Sialyl Lewis x (SLex) antigen
Oligosaccharides
Gastric epithelial progenitors (GEPs)
NeuAc(a2-3)Gal(b1-4)
Binding
HpaA
Sialyl Lewis x (SLex) antigen
Oligosaccharides
Gastric epithelial progenitors (GEPs)
NeuAc(a2-3)Gal(b1-4)
Binding
Displaying entries 1481 - 1490 of 1840 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01