Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Database | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
|
Adhesins
|
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
|
Oligoglycosylceramides
|
Pharyngeal epithelial cells
|
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
CS3 (coli surface 3)-fimbriae
|
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
|
Oligoglycosylceramides
|
Intestinal epithelium, Rabbit intestine
|
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
P-fimbriae
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Human erythrocytes
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Fimbriae
|
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
|
Oligoglycosylceramides
|
Human pharyngeal epithelial cells
|
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
66-kDa subunit
|
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
|
Oligoglycosylceramides
|
Human buccal epihelial cells (BECs)
|
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
P-fimbriae
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Human erythrocytes
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
|
Type 4-pili
|
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
|
Oligoglycosylceramides
|
Epithelial cells
|
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Type 4-pili
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Epithelial cells
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Shiga-like toxin (Stx1)
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
GI/kidney
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Shiga toxin (Stx2)
|
Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)
|
Oligoglycosylceramides
|
Vero cells
|
Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
Displaying entries 1531 - 1540 of 1840 in total
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International Collaboration
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Acknowledgements
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
