PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Capsid protein VP1
|
Sialylated oligosaccharides
|
Oligosaccharides
|
Cell surface
|
NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc
|
Binding
|
||
Unknown
|
Sialylated type 2 chain conjugates (S-type 2-HSA)
|
Glycoproteins
|
Human serum albumin
|
NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD
|
Binding
|
||
Neutrophil-activating proteins (150-kDa)
|
Sialylparagloboside(NeuGc)
|
Monosialoglycosphingolipids
|
Rabbit thymus
|
NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
K99
|
Sialylparagloboside(NeuGc)
|
Monosialoglycosphingolipids
|
NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
|||
Unknown
|
Sialylparagloboside(NeuGc)
|
Monosialoglycosphingolipids
|
NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
|||
Unknown
|
Sphingomyelin
|
Non-glycosylated Lipids
|
Binding
|
||||
Adhesins
|
Sucrose
|
Monosaccharides
|
Human lung epithelial cell line (A549)
|
Binding
|
|||
Unknown
|
Sulfated glucuronyl paragloboside
|
Sulfoglycosphingolipids
|
Human colon adenocarcinoma cells (WiDr )
|
GlcA(3SO4)(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
FHA (filamentous hemagglutinin)
|
Sulfatide (CSE)
|
Sulfoglycosphingolipids
|
Cell surface
|
HSO3(-3)Gal(b1-1)Cer
|
Binding
|
||
Adhesins
|
Sulfatide (CSE)
|
Sulfoglycosphingolipids
|
Erythrocytes
|
HSO3(-3)Gal(b1-1)Cer
|
Binding
|
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01