Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Species Pathogen Adherence Molecule Ligand Name ▲ Ligand Feature Target Source Glycan Sequence Binding PubMed ID
Capsid protein VP1
Sialylated oligosaccharides
Oligosaccharides
Cell surface
NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc
Binding
Unknown
Sialylated type 2 chain conjugates (S-type 2-HSA)
Glycoproteins
Human serum albumin
NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD
Binding
Neutrophil-activating proteins (150-kDa)
Sialylparagloboside(NeuGc)
Monosialoglycosphingolipids
Rabbit thymus
NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
Not Binding
K99
Sialylparagloboside(NeuGc)
Monosialoglycosphingolipids
NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
Binding
Unknown
Sialylparagloboside(NeuGc)
Monosialoglycosphingolipids
NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
Not Binding
Unknown
Sphingomyelin
Non-glycosylated Lipids
Binding
Adhesins
Sucrose
Monosaccharides
Human lung epithelial cell line (A549)
Binding
Unknown
Sulfated glucuronyl paragloboside
Sulfoglycosphingolipids
Human colon adenocarcinoma cells (WiDr )
GlcA(3SO4)(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
Binding
FHA (filamentous hemagglutinin)
Sulfatide (CSE)
Sulfoglycosphingolipids
Cell surface
HSO3(-3)Gal(b1-1)Cer
Binding
Adhesins
Sulfatide (CSE)
Sulfoglycosphingolipids
Erythrocytes
HSO3(-3)Gal(b1-1)Cer
Binding
Displaying entries 1561 - 1570 of 1840 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01