GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Glycan Sequence	Binding ▲	PubMed ID
Influenza virus	Unknown	GT1b	Trisialoglycosphingolipids	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	7870741
Rotavirus	Unknown	GT1b	Trisialoglycosphingolipids	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	11160731
Yersinia pestis	PsaA/B (pH-6 antigen)	GT1b	Trisialoglycosphingolipids	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	9712817
Cytomegalovirus	Unknown	GT1b	Trisialoglycosphingolipids	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	9780061
Helicobacter pylori	Unknown	GT1b	Trisialoglycosphingolipids	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	9169796
Rotavirus	Unknown	Lactosylceramide (d18:1-16:0/24:1)	Diosylceramides	Gal(b1-4)Glc(b1-1)Cer	Not Binding	11160731
Escherichia coli	F1C	Gb2 (Galabiosylceramide)	Diosylceramides	Gal(a1-4)Gal(b1-1)Cer	Not Binding	10816509
Propionibacterium granulosum	Lectin-like proteins (adhesin)	Gb2 (Galabiosylceramide)	Diosylceramides	Gal(a1-4)Gal(b1-1)Cer	Not Binding	2468365
Norovirus	Unknown	Blood group A antigen (A-tri-HSA)	Glycoproteins	GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Not Binding	18701592
Norovirus	Unknown	Blood group B antigen (B-tri-HSA)	Glycoproteins	Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Not Binding	18701592