GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name ▲	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Polyoma virus	Unknown	unnamed ligand	Oligosaccharides	Murine small plaque	NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc	Binding	8574698
Escherichia coli	K1	unnamed ligand	Disaccharides	Endothelial cells	GlcNAc(b1-4)GlcNAc	Binding	16564136
Actinomyces naeslundii	Type-2 fimbrial lectins (130-kDa glycoprotein)	unnamed ligand	Oligosaccharides	Polymorphonuclear leukocytes (PMNs)	Gal(b1-3)GalNAc	Binding	7790078
Streptococcus suis	PO	unnamed ligand	Oligosaccharides	human erythrocytes	Gal(a1-4)Gal	Binding	7499414
Clostridium difficile	Toxin A	unnamed ligand	Oligosaccharides	Human colonic cells	Gal(a1-3)Gal(b1-4)GlcNAc	Binding	12507507
Clostridium difficile	C-terminal domain of toxin A molecules	unnamed ligand	Oligosaccharides	Human colonic cells	Gal(a1-3)Gal(b1-4)GlcNAc	Binding	12507507
Streptococcus suis	PN	unnamed ligand	Oligosaccharides	human erythrocytes	Gal(a1-4)Gal	Binding	7499414
Legionella pneumophila	Adhesins	unnamed ligand	Oligosaccharides	Human epithelial cells (respiratory tract)	Gal(b1-4)GlcNAc	Binding	14687561
Campylobacter jejuni	Unknown	unnamed ligand	Oligosaccharides	Intestinal cells	Fuc(a1-2)Gal(b1-4)GlcNAc	Binding	16564136
Pseudomonas aeruginosa	Unknown	unnamed ligand	Oligosaccharides	Respiratory tract	Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc	Binding	16564136