GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID ▲
Theiler's murine encephalomyelitis virus	Unknown	Heparan sulfate	Glycosaminoglycans	Central nervous system		Binding	16575521
Theiler's murine encephalomyelitis virus	VP2 amino acids on puff B	Sialic acid (α2,3)	Saccharides	Central nervous system	NeuAc(a2-3)	Binding	16575521
Norovirus	Unknown	Blood group O antigen	Oligosaccharides	Human saliva		Binding	16707048
Norovirus	Unknown	Terminal N-Acetylgalactosamine residue in an alpha linkage	Saccharides	Oyster digestive tissues		Binding	16707048
Norovirus	Unknown	Blood group B antigen	Oligosaccharides	Human saliva	Gal(a1-3)[Fuc(a1-2)]Gal	Not Binding	16707048
Norovirus	Unknown	Blood group A antigen	Oligosaccharides	Human saliva	GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc	Binding	16707048
Neisseria meningitidis	33-kDa proteins	factor H (fH)	Glycoproteins			Binding	16751403
Pseudomonas aeruginosa	PA-IIL	Blood group H antigen	Disaccharides		Fuc(a1-2)Gal	Binding	16762477
Ralstonia solanacearum	RSL (30-kDa proteins)	Blood group H antigen	Disaccharides		Fuc(a1-2)Gal	Binding	16762477
Ralstonia solanacearum	RS-IIL (homologous to PA-IIL)	Mannose	Monosaccharides		Man	Binding	16762477