PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
HMW2
|
Oligosaccharides rich in sialic acid
|
Oligosaccharides
|
Human epithelial cells
|
Binding
|
|||
B subunit
|
unnamed ligand
|
Glycosphingolipids
|
Human meconium
|
Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
Natural ligand of integrin [alpha]v[beta]3
|
De-N-sulfated heparin
|
Glycosaminoglycans
|
Extracellular matrix (ECM)
|
Not Binding
|
|||
Unknown
|
GD2
|
Disialoglycosphingolipids
|
GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
|||
Unknown
|
GT1b analog
|
Trisialoglycosphingolipids
|
Synapse
|
Binding
|
|||
PA-IL
|
Melibiose
|
Disaccharides
|
Gal(a1-6)Glc
|
Binding
|
|||
Unknown
|
Sulfatide (CSE)
|
Sulfoglycosphingolipids
|
HSO3(-3)Gal(b1-1)Cer
|
Binding
|
|||
Membrane-associated lectins (heavy(170-kDa)/light(35-or31-kDa) subunits)
|
N-Acetylgalactosamine
|
Monosaccharides
|
GalNAc
|
Binding
|
|||
Unknown
|
B-GM1
|
Monosialoglycosphingolipids
|
Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
|||
Adhesins
|
Gb4 (Globoside; Globotetraose; P antigen)
|
Oligoglycosylceramides
|
Erythrocytes
|
GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01