GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name ▲	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Shigella dysenteriae	B subunit	unnamed ligand	Oligoglycosylceramides	Rat small intestine	[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5	Not Binding	3543013
Actinomyces naeslundii	Unknown	unnamed ligand	Oligoglycosylceramides	Various sources	Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Actinomyces naeslundii	Unknown	unnamed ligand	Oligoglycosylceramides	Various sources	GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Escherichia coli	P-fimbriae	unnamed ligand	Oligoglycosylceramides		Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-6)[Gal(b1-3)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	7721812
Shigella dysenteriae	Shiga toxin	unnamed ligand	Oligoglycosylceramides		[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5	Not Binding	2435422
Escherichia coli	Unknown	unnamed ligand	Oligoglycosylceramides		[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5	Binding	2435422
Shigella dysenteriae	Unknown	unnamed ligand	Oligoglycosylceramides		[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5	Not Binding	2435422
Staphylococcus haemolyticus	17-kDa HBP (Heparin-binding protein)	von Willebrand factor (VWF)	Glycoproteins			Binding	11393292
Staphylococcus epidermidis	17-kDa HBP (Heparin-binding protein)	von Willebrand factor (VWF)	Glycoproteins			Binding	11393292
Clostridium difficile	Toxin A	α-Gal on Fab of IgA(κ) MAb	Glycoproteins	Mouse	Gal	Binding	9573079