GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID ▲
Escherichia coli	hLT	Blood group A antigen analog	Oligosaccharides			Binding	18809496
Borrelia burgdorferi	BBK32	GAGs (glycosaminoglycans)	Glycosaminoglycans			Binding	18833295
Borrelia burgdorferi	BBK32	Fibronectin	Glycoproteins			Binding	18833295
Norovirus	Unknown	Sialylated type 2 chain conjugates (S-type 2-HSA)	Glycoproteins	Human serum albumin	NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD	Binding	19054801
Norovirus	Unknown	Sialyl Lewis x (SLex-HSA)	Glycoproteins	Human serum albumin	NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD	Binding	19054801
Norovirus	Unknown	Blood group B antigen (B-tri-HSA)	Glycoproteins	Human serum albumin	Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	19054801
Norovirus	Unknown	Blood group A antigen (A-tri-HSA)	Glycoproteins	Human serum albumin	GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	19054801
Norovirus	Unknown	Sialyl-dimeric Lewis x (SdiLex-HSA)	Glycoproteins	Human serum albumin	NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD	Binding	19054801
Norovirus	Unknown	Blood group H1 antigen (HSA)	Glycoproteins	Human serum albumin	Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD	Binding	19054801
Norovirus	Unknown	Lewis b (Leb-HSA)	Glycoproteins	Human serum albumin	Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD	Binding	19054801