GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Lactobacillus johnsonii	Unknown	Lactotriaosylceramide (Lc3)	Oligoglycosylceramides		GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	11087711
Mycoplasma pneumoniae	Unknown	GT1b	Trisialoglycosphingolipids	Human colon adenocarcinoma cells (WiDr )	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	2470753
Clostridium botulinum	Unknown	Lactose	Disaccharides	Intestine-407 cells	Gal(b1-4)Glc	Binding	15850798
Escherichia coli	PrsG (class III)	SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5)	Monosialoglycosphingolipids	Human kidney tissues	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9673272
Clostridium tetani	Tetanus toxin	GQ1b	Tetrasialoglycosphingolipids		NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	7527546
Streptococcus gordonii	SspB (Antigen I/II)	Salivary glycoprotein	Glycoproteins	Saliva		Binding	12640357
Listeria monocytogenes	Unknown	Mannose 6-phosphate insulin-like growth factor-II receptor (M6P/IGF-IIR)	Glycoproteins	Fetal calf serum		Binding	16369013
Escherichia coli	P-fimbriae	GL-III glycolipid	Glycolipids			Binding	7721812
Clostridium botulinum	Unknown	GD2	Disialoglycosphingolipids		GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Poliovirus	Unknown	CD155	Glycoproteins			Binding	12663789