GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding ▲	PubMed ID
Actinomyces odontolyticus	Type 2-fimbriae	β-linked galactosamine	Saccharides	Plaque	GalNAc(b 2:2	Binding	9712794
Escherichia coli	18-kDa fimbrial adhesin	Galactose derivatives	Saccharides	HEp-2 cells	Gal	Binding	11368522
Escherichia coli	F1C	unnamed ligand	Saccharides	Urine	GalNAc(b1-4)Gal(b	Binding	16564136
Actinomyces naeslundii	Type-2 fimbrial lectins	GD1a	Disialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	3804448
Actinomyces naeslundii	Type-2 fimbrial lectins	GD1b	Disialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	3804448
Escherichia coli	K99	GD1a(NeuGc)	Disialoglycosphingolipids		NeuGc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	7849044
Vibrio cholerae	Cholera toxin	GD1b	Disialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	8574698
Vibrio cholerae	Cholera toxin	GD1b	Disialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	3290106
Vibrio cholerae	Cholera toxin	GD1b	Disialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	7527546
Escherichia coli	Heat-labile enterotoxin (type II(LT-Iia))	GD1a	Disialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	3290106