GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Neisseria gonorrhoeae	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	12628483
Campylobacter upsaliensis	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	8926069
Neisseria gonorrhoeae	Fimbriae	Lactosylceramide (Lactocerebroside)	Diosylceramides		Gal(b1-4)Glc(b1-1)Cer	Binding	10816509
Escherichia coli	AC/I-fimbriae (S-fimbrial family)	unknown carbohydrate ligand	Saccharides	Septicemic avian epithelial cells		Binding	10992500
Mycoplasma pneumoniae	Unknown	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides		GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	3413084
Shigella dysenteriae	Shiga toxin	unnamed ligand	Oligoglycosylceramides		GalNAc(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2435422
Escherichia coli	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	3413084
Shigella dysenteriae	Shiga toxin	Gal-nLc4Cer; P1 antigen (GSL)	Oligoglycosylceramides		Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2435422
Staphylococcus aureus	FnbA	Fibronectin	Glycoproteins			Binding	12640357
Streptococcus pneumoniae	Adhesins	D-Mannose	Monosaccharides	Type-II lung cells, Vascular endothelial cells	Man	Binding	7752878